The present disclosure relates generally to wound dressing compositions and methods of manufacturing the wound dressing compositions of the present technology. The wound dressing composition includes a mixture of a collagen and/or chitosan and oxidized regenerated cellulose (ORC) with a layer of citric acid disposed therein. Also disclosed herein are methods of manufacturing such wound dressing compositions as well as kits including such wound dressing compositions.

The present disclosure relates generally to wound dressing compositions and methods of manufacturing the wound dressing compositions of the present technology. The wound dressing composition includes a mixture of a collagen and/or chitosan and oxidized regenerated cellulose (ORC) with a layer of citric acid disposed therein. Also disclosed herein are methods of manufacturing such wound dressing compositions as well as kits including such wound dressing compositions.

The present disclosure provides wound dressing compositions that disrupt biofilm formation in a wound upon application. The wound dressing composition includes a first layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), and at least one bacteria reducing active ingredient and a second layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), a silver compound, and at least one bacteria reducing active ingredient, and the uses thereof. Also disclosed herein are kits comprising the wound dressing compositions of the present technology, and instructions for use.

The present disclosure provides wound dressing compositions that disrupt biofilm formation in a wound upon application. The wound dressing composition includes a first layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), and at least one bacteria reducing active ingredient and a second layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), a silver compound, and at least one bacteria reducing active ingredient, and the uses thereof. Also disclosed herein are kits comprising the wound dressing compositions of the present technology, and instructions for use.

Patterned fibrous substrates having a plurality of individual fibers, a first region, and a second region are provided. The patterned fibrous substrates have a plurality of individual fibers of the first region having a first diameter and a plurality of individual fibers of the second region have a second diameter, wherein the first diameter is less than the second diameter. The individual fibers of the first region and the individual fibers of the second region are substantially free of bonds, other than primary bonds. The first region has a first C.I.E. L* score, and the second region has a second C.I.E. L* score, according to the Color Test Method. The first C.I.E. L* score is different than the second C.I.E. L* score.

Patterned fibrous substrates having a plurality of individual fibers, a first region, and a second region are provided. The patterned fibrous substrates have a plurality of individual fibers of the first region having a first diameter and a plurality of individual fibers of the second region have a second diameter, wherein the first diameter is less than the second diameter. The individual fibers of the first region and the individual fibers of the second region are substantially free of bonds, other than primary bonds. The first region has a first C.I.E. L* score, and the second region has a second C.I.E. L* score, according to the Color Test Method. The first C.I.E. L* score is different than the second C.I.E. L* score.

The present disclosure provides a magnetic dressing and a preparation method and use thereof, belonging to the technical field of pharmaceutical preparations. The magnetic dressing includes a magnetic layer, a drug-loading layer, and a protective layer that are stacked in sequence, where the magnetic layer includes polyvinyl alcohol, gluten, and iron particles. In the present disclosure, a swallowed magnetic dressing is controlled by an external magnetic field, and the magnetic dressing is moved to a pathological position by changing a direction of the external magnetic field; after the external magnetic field is removed, the magnetic dressing changes from a ring to a sheet, thereby completing attachment of an entire lesion surface to complete treatment by autonomous drug release.

The present disclosure provides a magnetic dressing and a preparation method and use thereof, belonging to the technical field of pharmaceutical preparations. The magnetic dressing includes a magnetic layer, a drug-loading layer, and a protective layer that are stacked in sequence, where the magnetic layer includes polyvinyl alcohol, gluten, and iron particles. In the present disclosure, a swallowed magnetic dressing is controlled by an external magnetic field, and the magnetic dressing is moved to a pathological position by changing a direction of the external magnetic field; after the external magnetic field is removed, the magnetic dressing changes from a ring to a sheet, thereby completing attachment of an entire lesion surface to complete treatment by autonomous drug release.

Provided are: a water-absorbing agent achieving, in a balanced manner, both good physical properties and a decrease in speed of coloration with lapse of time even if the water-absorbing agent has a high moisture absorbing speed due to having a large specific surface area; and an absorbent body having a low ratio of pulp and achieving, in a balanced manner, both good physical properties suitable for a thin disposable diaper and a decrease in speed of coloration with lapse of time. The absorbent body contains a hydrophilic base material and a water-absorbing agent which contains: surface-crosslinked water-absorbing resin particles having a non-uniformly pulverized shape; α-hydroxycarboxylic acid (salt); and an aminocarboxylic acid-based chelating agent and/or a phosphorus-based chelating agent, a point plotted along an x-axis that represents an amount (x.sub.1 mol %) of α-hydroxycarboxylic acid (salt) extracted from the water-absorbing agent and along a y-axis that represents an amount (y.sub.1 mmol %) of an aminocarboxylic acid-based chelating agent and/or a phosphorus-based chelating agent extracted from the water-absorbing agent being within a range that satisfies a specific relational formula of x.sub.1 and y.sub.1, the water-absorbing agent having a moisture absorbing speed of 120 mg/g/hr or more at a temperature of 40±1° C. at a relative humidity of 75±1% RH.

Provided are: a water-absorbing agent achieving, in a balanced manner, both good physical properties and a decrease in speed of coloration with lapse of time even if the water-absorbing agent has a high moisture absorbing speed due to having a large specific surface area; and an absorbent body having a low ratio of pulp and achieving, in a balanced manner, both good physical properties suitable for a thin disposable diaper and a decrease in speed of coloration with lapse of time. The absorbent body contains a hydrophilic base material and a water-absorbing agent which contains: surface-crosslinked water-absorbing resin particles having a non-uniformly pulverized shape; α-hydroxycarboxylic acid (salt); and an aminocarboxylic acid-based chelating agent and/or a phosphorus-based chelating agent, a point plotted along an x-axis that represents an amount (x.sub.1 mol %) of α-hydroxycarboxylic acid (salt) extracted from the water-absorbing agent and along a y-axis that represents an amount (y.sub.1 mmol %) of an aminocarboxylic acid-based chelating agent and/or a phosphorus-based chelating agent extracted from the water-absorbing agent being within a range that satisfies a specific relational formula of x.sub.1 and y.sub.1, the water-absorbing agent having a moisture absorbing speed of 120 mg/g/hr or more at a temperature of 40±1° C. at a relative humidity of 75±1% RH.