A method for treating a skin disorder, e.g., acne, e.g. acne vulgaris, in a subject is provided. The method comprises administering, e.g., applying, e.g., topically administering, ammonia oxidizing bacteria, e.g., a preparation comprising ammonia oxidizing bacteria, to a surface of the subject. Preparations comprising ammonia oxidizing bacteria for treating such skin disorder, e.g., acne, e.g. acne vulgaris in a subject are also provided.

A method for treating a skin disorder, e.g., acne, e.g. acne vulgaris, in a subject is provided. The method comprises administering, e.g., applying, e.g., topically administering, ammonia oxidizing bacteria, e.g., a preparation comprising ammonia oxidizing bacteria, to a surface of the subject. Preparations comprising ammonia oxidizing bacteria for treating such skin disorder, e.g., acne, e.g. acne vulgaris in a subject are also provided.

This disclosure provides, inter alia, an optimized strain of Nitrosomonas eutropha (N. eutropha) designated D23, D23-100, or AOB D23-100. N. eutropha bacteria disclosed in this application have desirable properties, e.g., optimized properties, such as the ability to suppress growth of pathogenic bacteria, and an enhanced ability to produce nitric oxide and nitric oxide precursors. The N. eutropha herein may be used, for instance, to treat diseases associated with low nitrite levels, skin diseases, and diseases caused by pathogenic bacteria.

This disclosure provides, inter alia, an optimized strain of Nitrosomonas eutropha (N. eutropha) designated D23, D23-100, or AOB D23-100. N. eutropha bacteria disclosed in this application have desirable properties, e.g., optimized properties, such as the ability to suppress growth of pathogenic bacteria, and an enhanced ability to produce nitric oxide and nitric oxide precursors. The N. eutropha herein may be used, for instance, to treat diseases associated with low nitrite levels, skin diseases, and diseases caused by pathogenic bacteria.

The present invention relates to patch comprising a fibrous element comprising a filament-forming material and a microorganism, further comprising a liquid pervious first layer comprising a body facing surface and a garment facing surface opposite to the body facing surface,

an attachment means disposed at least partially on the garment facing surface of the first layer, and a removable release liner at least partially covering the attachment means when the attachment means comprises an adhesive.

The present invention relates to patch comprising a fibrous element comprising a filament-forming material and a microorganism, further comprising a liquid pervious first layer comprising a body facing surface and a garment facing surface opposite to the body facing surface,

an attachment means disposed at least partially on the garment facing surface of the first layer, and a removable release liner at least partially covering the attachment means when the attachment means comprises an adhesive.

Plant material has bacteriophage has been attached, wherein the bacteriophage retains infectivity. The plant material includes fruits, vegetables, leaves, stems, flowers, roots, tubers, seedlings and seeds. Plant diseases and animal diseases can be treated. A separate composition comprises a carrier selected from (i) a filament, (ii) a planar material, and (iii) particles and/or beads, and bacteriophage covalently attached thereto, wherein the bacteriophage retains infectivity, useful in treatment or prevention of bacterial infection in a deep wound.

Plant material has bacteriophage has been attached, wherein the bacteriophage retains infectivity. The plant material includes fruits, vegetables, leaves, stems, flowers, roots, tubers, seedlings and seeds. Plant diseases and animal diseases can be treated. A separate composition comprises a carrier selected from (i) a filament, (ii) a planar material, and (iii) particles and/or beads, and bacteriophage covalently attached thereto, wherein the bacteriophage retains infectivity, useful in treatment or prevention of bacterial infection in a deep wound.

A multi-lactobacillus composition is a dominant strain separated and selected from the vagina of a healthy woman in China. The multi-lactobacillus composition comprises at least three of the following active components: Lactobacillus johnsonii, Lactobacillus gasseri, Lactobacillus rhamnosus, Lactobacillus crispatus, and Lactobacillus jensenii.

The present disclosure provides functional fibrous material comprising fibers associated with hydrogel containing micro-flakes. The present disclosure also provides a method of forming hydrogel micro-flakes having embedded therein at least one microorganism and a method of preparing functional fibrous material, both methods comprise a step of subjecting a mixture of hydrogel and microbial material to high shear forces to form micro-flakes comprising the hydrogel with at least one microorganism embedded therein. Further provided is a method of treatment of a target comprising contacting the target with the disclosed functional fibrous material as well as the micro-flakes disclosed herein.