A water permeability-imparting agent containing an alkylene oxide adduct (A) of a polyvalent active hydrogen compound represented by Formula (1):

R—[O(A.sup.1O).sub.m—(CH.sub.2CH.sub.2O).sub.n—H].sub.1   (1)

wherein R represents a residue, after removal of all active hydrogen, of the polyvalent active hydrogen compound; A.sup.1O represents a C2 to C4 alkyleneoxy group; m represents an average addition mole number of A.sup.1O and is a number of 4 to 50; n represents an average addition mole number of CH.sub.2CH.sub.2O; and 1 represents a valence and is an integer of 3 to 6, and an average addition mole number ratio between A.sup.1O and CH.sub.2CH.sub.2O in Formula (1), n/m, is 0 to 0.5.

A water permeability-imparting agent containing an alkylene oxide adduct (A) of a polyvalent active hydrogen compound represented by Formula (1):

R—[O(A.sup.1O).sub.m—(CH.sub.2CH.sub.2O).sub.n—H].sub.1   (1)

wherein R represents a residue, after removal of all active hydrogen, of the polyvalent active hydrogen compound; A.sup.1O represents a C2 to C4 alkyleneoxy group; m represents an average addition mole number of A.sup.1O and is a number of 4 to 50; n represents an average addition mole number of CH.sub.2CH.sub.2O; and 1 represents a valence and is an integer of 3 to 6, and an average addition mole number ratio between A.sup.1O and CH.sub.2CH.sub.2O in Formula (1), n/m, is 0 to 0.5.

A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions.

In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.

A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions.

In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.

The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.

The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.

A curable composition for use in wound care comprising, apportioned between at least one Part A and at least one Part B: one or more alkenyl-group containing polymers (i) having at least one alkenyl group or moiety per molecule, one or more SiH-containing polymers (ii) having at least one Si—H unit per molecule; and a catalyst (iii) for curing by addition of alkenyl-containing polymer (i) to SiH-containing polymer (ii), Part A and Part B independently having viscosity at 23° C. in the range 5-300 Pa.Math.s, preferably 10-100 Pa.Math.s, at a shearing rate of 10 s.sup.−1, and when combined in one Part having cure time at 23° C. in the range from 0.5 min to 25 min, wherein when dispensed into a location about a wound dressing, said wound dressing overlying a wound site and skin thereabout, said dispensing being so as to intimately contact and overlie an edge of said dressing and skin about said edge, the composition cures in contact with said edge and skin at 32° C. to an elastomer exhibiting zero or low tack at a time in the range from 0.5 to less than 30 minutes, apparatus for use with said composition comprising dispensing apparatus or wound dressing, a kit comprising the same, and methods of dispensing and curing the same and of using the same in sealing a wound dressing and in treating a wound site of a human in need thereof.

A curable composition for use in wound care comprising, apportioned between at least one Part A and at least one Part B: one or more alkenyl-group containing polymers (i) having at least one alkenyl group or moiety per molecule, one or more SiH-containing polymers (ii) having at least one Si—H unit per molecule; and a catalyst (iii) for curing by addition of alkenyl-containing polymer (i) to SiH-containing polymer (ii), Part A and Part B independently having viscosity at 23° C. in the range 5-300 Pa.Math.s, preferably 10-100 Pa.Math.s, at a shearing rate of 10 s.sup.−1, and when combined in one Part having cure time at 23° C. in the range from 0.5 min to 25 min, wherein when dispensed into a location about a wound dressing, said wound dressing overlying a wound site and skin thereabout, said dispensing being so as to intimately contact and overlie an edge of said dressing and skin about said edge, the composition cures in contact with said edge and skin at 32° C. to an elastomer exhibiting zero or low tack at a time in the range from 0.5 to less than 30 minutes, apparatus for use with said composition comprising dispensing apparatus or wound dressing, a kit comprising the same, and methods of dispensing and curing the same and of using the same in sealing a wound dressing and in treating a wound site of a human in need thereof.

An absorbent article having a liquid permeable topsheet, a liquid impermeable sheet, an absorbent core disposed between the topsheet and the backsheet, and a secondary topsheet disposed between the topsheet and the absorbent core is described. The secondary topsheet has a first layer and a second layer. The first layer is located between the topsheet and the second layer, and a mean pore size of the first layer is larger than a mean pore size of the topsheet.

An absorbent article comprising a composition, said composition comprising a metathesized unsaturated polyol ester, said metathesized unsaturated polyol ester having one or more of the following properties: (i) a weight average molecular weight of from about 5,000 Daltons to about 50,000 Daltons; (ii) an oligomer index from greater than 0 to 1; (iii) an iodine value of from about 30 to about 200.