A new synthetic pathway for hyperbranched polyacrylates and polymethacrylates including the steps of preparing an inimer and polymerizing the inimer to form hyperbranched polymers or copolymers.

Provided is a livestock body protective material that includes (A) an emulsion obtained by dispersing a rubber-based macromolecule serving as a dispersoid in a dispersion medium including water as the main component, and (B) a coagulant blended according to need, and that is used to form a protective film for protecting a livestock's sick/injured area.

Provided is a livestock body protective material that includes (A) an emulsion obtained by dispersing a rubber-based macromolecule serving as a dispersoid in a dispersion medium including water as the main component, and (B) a coagulant blended according to need, and that is used to form a protective film for protecting a livestock's sick/injured area.

Described are polymers and methods of forming and using same.

Described are polymers and methods of forming and using same.

The present invention relates to the field of medicine, generally to the field of surgical and emergency medical wound covering means on the base of haemostatic composition designated as Hemoblok. The invention proposes a new method of usage of these haemostatic compositions to activate the formation of artificial clots that can adhere to wounded tissue for the suppression of fluid loss and for the protection of viable tissue. The method consists of the steps to be applied to the open wound a grid-forming water-soluble haemostatic Hemoblok composition consisting of a polyacrylic matrix as an active ingredients, creating by Hemoblok the clot formation with the blood plasma proteins, preferably with albumin, creating a structure containing albumin molecules in the cells of the polyacrylic matrix (grid), which is the primary organizer of sustainable polyacrylic film, further forming by Hemoblok the multilayered solid polyacrylic film, then the replacement by fibrin of the surface structure hemoblok-protein and implementation of plasma formation of the polyacrylic matrix. Another object of the invention is a kit for creation of wound covering, comprising, packaged in association a Hemoblok composition, and a dispenser for applying the Hemoblok to open wounds, which is made as a woven or a non-woven fabric, a tube, a bandage or a container having at least one opening.

The present invention relates to the field of medicine, generally to the field of surgical and emergency medical wound covering means on the base of haemostatic composition designated as Hemoblok. The invention proposes a new method of usage of these haemostatic compositions to activate the formation of artificial clots that can adhere to wounded tissue for the suppression of fluid loss and for the protection of viable tissue. The method consists of the steps to be applied to the open wound a grid-forming water-soluble haemostatic Hemoblok composition consisting of a polyacrylic matrix as an active ingredients, creating by Hemoblok the clot formation with the blood plasma proteins, preferably with albumin, creating a structure containing albumin molecules in the cells of the polyacrylic matrix (grid), which is the primary organizer of sustainable polyacrylic film, further forming by Hemoblok the multilayered solid polyacrylic film, then the replacement by fibrin of the surface structure hemoblok-protein and implementation of plasma formation of the polyacrylic matrix. Another object of the invention is a kit for creation of wound covering, comprising, packaged in association a Hemoblok composition, and a dispenser for applying the Hemoblok to open wounds, which is made as a woven or a non-woven fabric, a tube, a bandage or a container having at least one opening.

Stabilized pharmaceutical wound dressing compositions comprising calreticulin protein for use in medical treatment, in particular for topical treatment of acute and chronic wounds, are provided. Pharmaceutical compositions of the present invention comprise calreticulin protein or a functionally active fragment or derivative thereof and one or more of pharmaceutically acceptable polymeric materials that form hydrogel. More specifically, compositions of present invention can be sprayed onto a wound as a liquid or applied topically in the form of gel. Compositions of the present invention may further comprise serum albumins, preservatives and additional biologically active molecules.

Stabilized pharmaceutical wound dressing compositions comprising calreticulin protein for use in medical treatment, in particular for topical treatment of acute and chronic wounds, are provided. Pharmaceutical compositions of the present invention comprise calreticulin protein or a functionally active fragment or derivative thereof and one or more of pharmaceutically acceptable polymeric materials that form hydrogel. More specifically, compositions of present invention can be sprayed onto a wound as a liquid or applied topically in the form of gel. Compositions of the present invention may further comprise serum albumins, preservatives and additional biologically active molecules.

A method of promoting healing of a wound in a diabetic patient is disclosed that includes applying a hydrogel loaded with a therapeutically effective dosage of a TGF receptor II (TGF?RII) inhibitor to the wound.