This invention relates to a packaged sterile wound dressing comprising a dressing saturated with a pain relieving composition, a method of providing pain relief due to a wound of a subject using said dressing, and a method of manufacturing the packaged sterile wound dressing.

The present disclosure relates to wound dressings that support the cells in the wound area for the treatment of chronic wounds and eliminates the risk of infection development in open wounds. Specifically disclosed is a wound dressing material that includes graphene-based 2,3 dialdehyde bacterial cellulose. Additionally disclosed is a method for preparing the graphene-doped bacterial cellulose wound dressing material.

Disclosed are hydrogels polymerized with a biofunctional moiety, biodegradable and permanent, designed to be implantable in a mammalian body and intended to block or mitigate the formation of tissue adhesions. The hydrogels of the present invention are characterized by comprising four structural elements: a) a polymeric backbone which defines the overall polymeric morphology, b) linkage groups, c) side chains, and d) biofunctional end groups. The hydrophobicity of the various structural elements are chosen to reduce tissue adhesion and enhance the biofunctional aspect of the end groups. The morphology of these polymers are typically of high molecular weight and have shape to encourage entanglement. Useful structures include branching chains, comb or brush, and dendritic morphologies.

The present invention relates to an antimicrobial hydrogel wound dressing composition comprising an electro-activated superoxidised solution comprising hypochlorous acid, sodium hypochlorite, and sodium chloride, and also sodium hyaluronate. The present invention also provides a use for said wound dressing composition for acute and chronic wounds, as well as method of preparation for making the same.

A composition has an enzyme that is able to convert a substrate to release hydrogen peroxide; a substrate for the enzyme; and a superabsorbent component, such as a superabsorbent polymer. The composition is in the form of a powder and may form a gel on contact with water.

Hydrogels are provided that include an antimicrobial agent and a cross-linkable urethane-based polymer (CUP). Such hydrogels may be used for the controlled-release of antimicrobial agents as well as in the manufacturing of wound dressings. Wound dressings are provided that comprise a hydrogel as defined herein.

This invention relates to anti-microbial active particles, compositions and uses thereof for inhibiting bacterial growth on surfaces or devices. This invention further discloses methods of making such anti-microbial active particles.

Wound dressings and methods for treating a wound are provided. The wound dressing can have an environment-facing side that includes a biocompatible material having a polymer crosslinked with an antimicrobial effective amount of a NO-donor and a woundfacing side including a biocompatible resinous matrix and an antifibrinolytic agent. The wound dressing can promote fibrin formation and rapid platelet aggregation, and has antimicrobial properties. The dressing can be applied directly to the wound.

The present disclosure provides a method for freeze-drying cells in a hydrogel comprising nanofibrillar cellulose, the method comprising providing a hydrogel comprising nanofibrillar cellulose, providing cells, combining the cells and the hydrogel comprising nanofibrillar cellulose to form a cell system, and freeze drying the cell system to obtain dried cells in a hydrogel comprising nanofibrillar cellulose. The present disclosure also provides a freeze-dried hydrogel comprising nanofibrillar cellulose and cells.

A preparation of nano silver/dual modified chitosan antibacterial hydrogel dressing with discoloration effect for wound infection judgement and hydrogel dressing prepared by the same provided. The preparation includes the following: carrying out quaternization water-soluble modification on high molecular weight chitosan, and carrying out catecholamination water-soluble modification to prepare dual water-soluble modified chitosan; reducing silver nitrate by using the dual water-soluble modified chitosan to prepare a nano silver/dual water-soluble modified chitosan solution; adding the dual water-soluble modified chitosan, the nano silver/dual water-soluble modified chitosan, curcumin, zwitterion, acrylamide, a cross-linking agent and an initiator into deionized water in sequence, mixing and stirring uniformly, centrifugal de-foaming and casting, to prepare a nano silver/dual modified chitosan antibacterial color-changing hydrogel dressing by one-pot in-situ radical polymerization. The nano silver/dual modified chitosan antibacterial hydrogel dressing exhibits great potential for application in fields such as intelligent indicative wound repair hydrogel dressing and the like.