Hydrocolloid composition and bio-patch comprising the same are provided. The hydrocolloid composition has a hydrophobic elastomer matrix. Hydrocolloid particles and aerogel particles are dispersed in the matrix. The aerogel particles may be silica aerogel particles. The aerogel particles may include particles having hydrophobic functional groups formed on the particle surface. The aerogel particles may be hydrophobic aerogel particles, hybrid aerogel particles in which hydrophobic functional groups and hydrophilic functional groups are simultaneously formed on the particle surface, or a mixture of the hydrophobic aerogel particles, the hybrid aerogel particles, and hydrophilic aerogel particles.

A hot melt wetness indicator comprising an adhesive base composition utilizing a halogen-free species, namely nitrazine yellow, to trigger color change in hygiene articles, such as disposable diapers, to serve as moisture or wetness indicator upon insult. In some embodiments of the invention, the wetness indicator turns from yellow to purple.

The present disclosure relates to a film for oral hemostasis and wound protection and, more particularly, to a film for oral hemostasis and wound protection which, being attached to a wound area in an oral cavity, delays or prevents microbleeds and controls medicinal component release. The film provided by the present disclosure is capable of including a polyol, an alcohol and a biodegradable polymer in the state of partial swelling, thereby locally absorbing blood or pus or arresting hemorrhage. Moreover, due to its high elongation ratio, the film provided by the present disclosure is capable of maintaining its adhesive force even when having blood, saliva and pus absorbed inside an oral cavity and conveniently deforming according to the shape of a seriously corrugated local area, which causes only slight foreign body sensation even after a long period of time of attachment on to the local area. In addition, the film provided by the present disclosure includes a disintegrant which is dissolved and released by reacting with blood to form microchannels that act as paths for drug release and is capable of adjusting the amount and the size of the microchannels, thereby controlling the amount of drug release. The present disclosure doesn't require a patient to detach the film attached inside an oral cavity by hand because the adhesive layer and the backing layer dissolve entirely over time.

A method of using a film-forming material for pre-treating an area of skin to reduce friction-related skin irritation, resulting in a reduced risk of acquiring skin chafing and/or blisters, such as may be caused by the wearing of shoes that abrade skin, and particularly including heels, said method comprising the steps of providing a dispensing device containing a film-forming material that includes a friction-reducing and/or friction-blocking element, and applying such film-forming material to an area of skin to reduce friction and thereby reduce the risk of acquiring chafing and/or a blister.

The invention relates to a functional wound dressing being able to provide substances supporting the healing of a wound to the wound depending on the condition of the wound. In particular, in case of an infection which is reported to be frequently associated with poorly healing wounds, such as chronic wounds, a therapeutic substance is provided to the wound whereas in other cases no therapeutic substance is provided. The present wound dressing can be used in moist wound healing and contains a substance being able to absorb wound exudate from the wound and to provide moisture to the wound.

The subject of the present invention is a composite wound packing material comprising a casing enclosing a material, or an assembly of materials, forming fluid flow channels, said casing being composed of a self-supporting interface material formed from a thin layer of a composition comprising a hydrophobic matrix and comprising through-holes, said hydrophobic matrix comprising, per 100 parts by weight of a styrene/saturated olefin/styrene triblock copolymer having a viscosity of between 0.2 and 2 Pa.Math.s, as measured in a 10% (weight/weight) solution in toluene, from 400 to 1220 parts by weight of a plasticizer, preferably a plasticizing oil, and from 0 to 720 parts by weight of petroleum jelly, it being specified, moreover, that the total amount of plasticizer and petroleum jelly is greater than or equal to 750 parts by weight and the amount of petroleum jelly is between 400 and 720 parts by weight when the amount of plasticizer is between 1000 and 1220 parts by weight.

A garment using a phase change material that change phase from solid to liquid at a low or high temperatures situated within a gel matrix. The phase change material may be used after surgical procedures to reduce swelling, edema and bruising. The gel matrix allows the material of the present invention to maintain a conformable and elastic form at room temperature. This invention provides the novelty of a low or high temperature phase change material that is conformable to surfaces or volumes of varying geometry.

A method of forming a fibrin hydrogel composition is described. The method comprises forming an aqueous solution comprising fibrinogen, fibrin-forming enzyme, and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further comprises reducing the salt concentration below the threshold concentration to form a fibrin hydrogel. In some embodiments, the aqueous solution further comprises a plasticizer. A fibrin composition is also described comprising a fibrin hydrogel having a fibrin concentration ranging from 0.1 to 10 wt-%; and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt has a concentration less than a threshold concentration to form the fibrin hydrogel. The fibrin hydrogel or dehydrated fibrin hydrogel can be in various physical forms such a sheet, foam, or plurality of pieces. Also described are methods of forming a fibrin article, wound dressings and a method of treatment of a wound.

A method of forming a fibrin hydrogel composition is described. The method comprises forming an aqueous solution comprising fibrinogen, fibrin-forming enzyme, and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further comprises reducing the salt concentration below the threshold concentration to form a fibrin hydrogel. In some embodiments, the aqueous solution further comprises a plasticizer. A fibrin composition is also described comprising a fibrin hydrogel having a fibrin concentration ranging from 0.1 to 10 wt-%; and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt has a concentration less than a threshold concentration to form the fibrin hydrogel. The fibrin hydrogel or dehydrated fibrin hydrogel can be in various physical forms such a sheet, foam, or plurality of pieces. Also described are methods of forming a fibrin article, wound dressings and a method of treatment of a wound.

Disclosed are compositions and methods for treating wounds and damaged tissue using decidua tissue.