An applicator for use in tissue treatment, a method and a kit using the same. The applicator includes (i) a first chamber for holding whole blood, (ii) a second chamber for holding a coagulation initiator, and (iii) a dispensing element configured for concomitantly receiving, upon actuating the applicator, a volume of whole blood from said first chamber and a volume of coagulation initiator from said second chamber and dispensing the two together onto a tissue in need of treatment.

An aqueous extract of Lawsonia inermis comprising forming an extraction from 1% to 20% of dried Lawsonia inermis leaves with water. The antibiotics polymyxin B, clindamycin, and gentamycin are each added to the water before or after extraction in the amount of 0.001% to 0.003%. After forming the aqueous extract of Lawsonia inermis, it has no antibiotic activity and the antibiotics are not detectable by chemical analysis. The aqueous extract of Lawsonia inermis is stable for at least 28 days for the topical treatment of wounds and has been stable up to two years in clinical testing. The aqueous extract of Lawsonia inermis extract is applied with a spray to the surface of the wound, followed by the application of an extract-soaked gauze dressing to the surface of the wound. The extract is effective on various types of wounds and also in healing wounds in patients who are not healing with traditional therapies.

The present disclosure provides a sterile saline topical formulation comprising a primary polyamine in a normal saline solution of about 0.9% w/w of NaCl. It further provides the use of the formulation for treating or promoting the wound healing (e.g., burn, (open) sore), for preventing skin inflammation, skin irritation, skids sign of aging, or preventing or reducing the formation of hypertrophic scar tissue on a subject.

Copper ion treatments for dermatological areas of the body include solutions, creams, lotions, gets, foams, wound dressings, skin patches and suture material, each containing copper ions that bring about therapeutic effects when the copper ion treatments are applied to dermatological tissue. Methods of treating dermatological areas of the body include treatments for use on the skin and nails to treat conditions including disease, infection, inflammation, damaged or injured tissue, tissue needing to be sutured, rashes and other undesirable dermatological conditions.

A waterproof and air-permeable moist dressing which moisturizes and enhances color for aftercare of fresh tattoo. Therefore, the waterproof and air-permeable moist dressing can provide professional and medical repair, protection, isolation, and absorption of wound exudates and tattoo inks after tattooing to improve the aesthetical beauty of the tattoo.

A waterproof and air-permeable moist dressing which moisturizes and enhances color for aftercare of fresh tattoo. Therefore, the waterproof and air-permeable moist dressing can provide professional and medical repair, protection, isolation, and absorption of wound exudates and tattoo inks after tattooing to improve the aesthetical beauty of the tattoo.

A composition to treat atopic dermatitis having a combination of Siberian Sea Buckthorn Berry Oil at 98.0 to 99.99 of total combination percent weight; and nano diamonds at 2.0 to 0.01 of total combination percent weight respectively. In one approach, the Siberian Sea Buckthorn Berry Oil may be 99.6 to 99.8 of total combination percent weight; and the nano diamonds may be 0.02 to 0.04 of total combination percent weight respectively. In another approach, the composition may have a range of 3-8 ml of the Siberian Sea Buckthorn Berry Oil and nano diamond combination per 59 ml of a cream having 2 percent hydrocortisone. In yet another approach the composition may have 5 ml of Siberian Sea Buckthorn Berry Oil and nano diamond combination per 59 ml of a cream having 2 percent hydrocortisone.

The present invention relates to in vitro cultured senescent cells, such as epithelial cells, keratinocytes and/or fibroblasts as well as their use in the treatment of tissue regeneration, particularly for the treatment of wounds such as burns or ulcers or the treatment of inflammatory conditions. Optionally, products may be used in combination with further drugs including antimicrobial or antidiabetic agents.

The present invention provides compositions and methods to enhance cutaneous wound healing in subjects afflicted with, or at risk for, a pulmonary infection and/or a pulmonary injury. More specifically, the embodiments of the present invention relate to using fibrin carrier as a vehicle to topically deliver one or more chemokine onto a cutaneous wound so as to accelerate wound healing.

The present invention refers to a composition, comprising hemoglobin or myoglobin, wherein in at least 40% of said hemoglobin or myoglobin the oxygen binding site is charged by a non-O.sub.2 ligand, and at least one further ingredient, a method for preparing said composition and the use of hemoglobin or myoglobin charged with a non-oxygen ligand for external treatment of wounds.