Patent classifications
A61L26/0085
Biomedical foams
The invention relates, generally, to porous absorbent materials which are suitable for packing antrums or other cavities of the human or animal body. More particularly, it relates to hydrophilic biodegradable foams, which may be used e.g. in the form of a plug or tampon, for instance for controlling bleeding, wound closure, prevent tissue adhesion and/or support tissue regeneration. The invention provides an absorbent foam, suitable for packing antrums or other cavities of the human or animal body, comprising a biodegradable synthetic polymer, which polymer preferably comprises C(O)O groups in the backbone of the polymer, for instance polyurethane and/or polyester units combined with polyethers.
Stable pharmaceutical foam
Provided are pharmaceutical foam compositions comprising a peptone, a peptide hydrolysate or an enzymatically-hydrolyzed protein prepared by enzymatic hydrolysis of a full-length protein; methods of preparation and uses thereof.
Biomedical foams
The invention relates, generally, to porous absorbent materials which are suitable for packing antrums or other cavities of the human or animal body. More particularly, it relates to hydrophilic biodegradable foams, which may be used e.g. in the form of a plug or tampon, for instance for controlling bleeding, wound closure, prevent tissue adhesion and/or support tissue regeneration. The invention provides an absorbent foam, suitable for packing antrums or other cavities of the human or animal body, comprising a biodegradable synthetic polymer, which polymer preferably comprises C(O)Ogroups in the backbone of the polymer, for instance polyurethane and/or polyester units combined with polyethers.
MEDICAL DEVICE, AND HYDROGEL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Disclosed by the present invention are a medical device, hydrogel, preparation method therefor, and use thereof. The hydrogel is formed by polymerization reaction of antibacterial polypeptide and a buffer solution, the antibacterial polypeptide being polypeptide or a polypeptide derivative thereof represented by the following amino acid sequence: Pro-Phe-Lys-Leu-Ser-Leu-His-Leu-NH.sub.2. The hydrogel of the present invention has self-healing properties, and can be injectable and degraded in vivo and in vitro, needs moderate time for complete degradation, and is degraded after the drug effect is fully achieved; the hydrogel has a remarkable inhibiting effect on growth and proliferation of bacteria and fungi, has antibacterial and anti-inflammatory activity and excellent hemostatic properties, and has the advantages such as small cytotoxicity, substantially expressing no hemolytic activity, and excellent biocompatibility; and the hydrogel according to the present invention is excellent in anti-adhesion activity, does not adhere to wounds, is quickly crosslinked at 37 C., has a excellent effect of preventing postoperative adhesion and has obvious advantages in clinical practice.
Hemostatic agent and method of production thereof
A composition and method of preparing the composition for rapid and effective hemostasis is provided. The composition includes a first agent to induce platelet plug formation, a second to induce vasoconstriction and a third agent for activation of coagulation cascade. The composition comprises of 0.01% to 5% of chitosan; 0.01% to 0.25% of potassium aluminum sulphate; and 0.01% to 0.25% calcium salt. The clotting time of the composition is in the range of 30s to 140s. A method of preparing the hemostatic composition is further disclosed. The composition is configured to control hemorrhage from oozing and pressured bleeding injury any site in human/animal body.
ARTIFICIAL DRESSING AND USE OF ARTIFICIAL DRESSING FOR PROMOTING WOUND HEALING
The present invention provides an artificial dressing and a use of the artificial dressing for promoting wound healing. The artificial dressing includes a gelatin and a fungal extract.
Flexible polyurethane foams with high water absorption capacity
Described herein is a process for producing a hydrophilic flexible polyurethane foam. Also described herein is a flexible polyurethane foam obtainable by such a process and a method of using such a flexible polyurethane foam for treating wounds.
Formed sheet product and hemostatic material
A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
SYSTEM FOR THE FORMATION OF FIBRIN FOAM
A device and method for forming fibrin foam, preferably utilizing a single container, comprising a base structured to be rotationally driven and including a separation chamber disposed and structured to receive a blood sample therein. The base includes a reaction chamber disposed in fluid communication with said separation chamber. The blood sample is separated into a plasma segment and a packed cell segment when subjected to sufficient centrifugation concurrent to the driven rotation of the base. According to structural features, and in some instances concurrent and continuous centrifugation, the plasma segment is directed from said separation chamber into said reaction chamber which includes sufficient quantities of gas and reactant composition to facilitate formation of fibrin foam therein concurrent to centrifugation. Further centrifugation of the fibrin foam and the inclusion of additional features such as a pressurized reaction chamber facilitate the formation of fibrin foam exhibiting varying chemical and/or physical properties.
MEDICAL MATERIAL AND PRODUCT AND PREPARATION METHOD THEREOF
The present disclosure discloses a medical material and a product and preparation method thereof. The medical material comprises a ferroelectric polymer, and optionally further comprises an inorganic ferroelectric particle. The composite membrane is prepared by experiencing at least one of annealing treatment, corona poling treatment, acid treatment, and ultrasonic treatment, and the acid treatment is conducted after the annealing treatment. The present disclosure further relates to a method for treating a composite membrane to regulate an antibacterial activity.