The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graft material are also provided.

Disclosed are anticoagulant and decoagulant methods, compositions and devices comprising calcium carbonate, particularly, comprising aragonite.

Decellularized plant tissues and the use of these plant tissues as scaffolds are disclosed herein. Particularly, decellularized plant tissues are functionalized such to allow for human cell adhesion, thereby allowing for their use as scaffolds for human cells. These scaffolds can then be used in a number of applications/markets, including as research tools for tissue engineering, regenerative medicine, and basic cellular biology.

Provided herein is a see-through transparent, stable, safe and (bio)degradable hydrogel-based particulate support medium, made of calcium alginate particles. The calcium alginate particles, or hybrid hydrogel particles, are characterized by a substantially homogeneous average particle size that ranges from 0.1 micrometer to 5 micrometer.

Disclosed is a biocomposite product with high microbial activity obtained by using bee bread, the method of obtaining this product and using of this biocomposite material for the coating of products like artificial materials, packaging, etc. to be used in areas requiring hygiene or their use as an intermediate raw material.

A nanocomposite derived from organic sources, including waste date seeds, pomegranate peels and camel knee bone. The nanocomposites can be used for the synthesis of surgical implants, are biodegradable, and do not require surgery for their removal. The nanocomposites contain nanoparticles of date seeds, pomegranate peels, camel knee bone, polymers, organic substances, and organic dyes. A method for the preparation of the nanocomposites includes molding the nanocomposites into organic bone screws, bone plates, and dental prosthetics.

An organic bone and joint replacement biomaterial includes a nanocomposite including a mixture of nanocellulose and nanostarch obtained from date seed, durum seed coat, moringa seed, fish bone, sheep jawbone, and olive seed. The organic bone and joint replacement biomaterial includes an antioxidant of one or more of a beet root dye, an ajwa date pigment, a blueberry dye, a black cumin seed pigment, a valvet apple peel dye. The organic bone and joint replacement biomaterial include an organic adhesive selected from the group of an Acacia arabica gel, agar gel media, and a moringa leaf extract. Further, it includes an organic composition of an arrowroot starch gel, pomegranate seed starch, and an animal-based glycerin. Further, it also includes an adhesive composition, a plasticizer and calcium oxide.

The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graft material are also provided.

Provided herein are scaffold biomaterials comprising a decellularised fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularised fungal tissue comprising a cellulose- or chitin-based 3-dimensional porous structure. Methods for preparing such scaffold biomaterials, as well as uses thereof as an implantable scaffold for supporting animal cell growth, for promoting tissue regeneration, for promoting angiogenesis, for a tissue replacement procedure, and/or as a structural implant for cosmetic surgery are also provided. Therapeutic treatment and/or cosmetic methods employing such scaffolds are additionally described.

A viscoelastic composition is disclosed which comprises (a) tris(hydroxymethyl)aminomethane or a salt thereof; (b) a phosphate buffer agent; and (c) a viscoelastic agent having an average molecular weight of about 100 to about 5,000,000.