The present disclosure provides a method for modifying a hydrogel lubricating coating on a surface of general equipment, and hydrogel lubricating coating-modified general equipment, belonging to the technical field of material surface modification. In the present disclosure, by combining catechol adhesion chemistry and free radical polymerization initiated by surface catalysis, the method can realize in-situ generation of free radicals at an interface of a substrate and a hydrogel monomer solution at room temperature, without external auxiliary conditions such as illumination or heating. The method can prepare the hydrophilic hydrogel lubricating coating on the surface of almost all existing substrates, which is especially suitable for lubricating modification on an inner surface of a non-translucent pipeline instrument, showing material versatility. Therefore, the method is suitable for the fields of surface engineering and biomedicine.

The invention relates to balloon coatings and their use in delivering drugs via a drug-eluting balloon. The delivery can be, e.g., to a vessel wall.

The invention relates to balloon coatings and their use in delivering drugs via a drug-eluting balloon. The delivery can be, e.g., to a vessel wall.

A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.

Provided are polymers having a repeating unit including at least one astaxanthin moiety. Also provided are processes for preparing the polymers and various uses thereof.

Provided are polymers having a repeating unit including at least one astaxanthin moiety. Also provided are processes for preparing the polymers and various uses thereof.

The invention relates to a medical device delivery system comprising a catheter shaft having a proximal end and a distal end portion; an expandable member provided at the distal end portion of the shaft, the expandable member having a delivery configuration and a deployed configuration; the expandable member being folded around the catheter shaft in its delivery configuration; characterized in that a coating is disposed on at least a portion of the outer surface area of the expandable member in its delivery configuration such that the coating does not cover portions of the expandable member located inside the folds of the expandable member in its delivery configuration; and an expandable medical device is mounted on the expandable member in the delivery configuration with the coating being disposed between the expandable member and the expandable medical device.

The invention relates to a medical device delivery system comprising a catheter shaft having a proximal end and a distal end portion; an expandable member provided at the distal end portion of the shaft, the expandable member having a delivery configuration and a deployed configuration; the expandable member being folded around the catheter shaft in its delivery configuration; characterized in that a coating is disposed on at least a portion of the outer surface area of the expandable member in its delivery configuration such that the coating does not cover portions of the expandable member located inside the folds of the expandable member in its delivery configuration; and an expandable medical device is mounted on the expandable member in the delivery configuration with the coating being disposed between the expandable member and the expandable medical device.

A thermoset polyisobutylene network polymer includes a polyisobutylene diol residue, a diisocyanate residue, and at least one crosslinking compound residue selected from the group consisting of a residue of a sorbitan ester and a residue of a branched polypropylene oxide polyol.

A thermoset polyisobutylene network polymer includes a polyisobutylene diol residue, a diisocyanate residue, and at least one crosslinking compound residue selected from the group consisting of a residue of a sorbitan ester and a residue of a branched polypropylene oxide polyol.