A plasticized nylon and a medical device including plasticized nylon. The medical device may be a dilatation balloon. Also disclosed are methods of plasticizing nylon.

A urinary catheter and container. The urinary catheter can include a catheter shaft attached to a handle and a coating disposed on an outer surface of the catheter shaft. The coating can include a hydrogel, water and/or glycerin, and a polyethylene gylcol (PEG). The PEG can have a molecular weight equal to or less than 600, for example one or more of polyethylene glycol (PEG) 300 and PEG 400. The coating can be applied in a wet state and remain wet for an extended period of time in the container, thereby obviating the need for a lubricant, such as a water sachet or gel package, to accompany the catheter in the container. The container can include a gas impermeable foil material. The container can include an adhesive tab covering a perforated section, the adhesive tab including a pull loop.

The present invention provides an elastomeric composition for making elastomeric articles having at least one layer, such as but not limited to condoms, which have a deformation stress or modulus below about 1.5 MPa at 500% extension, comprising at least one polymeric material, at least one plasticizer and optionally at least one coating. The elastomeric articles also have unique tactile and tensile properties, such as conformability and low radius of curvature.

A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.

Methods of varying the stiffness of polymeric medical tubes.

A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.

A fluid flow circuit assembly for a biological fluid processing device, comprising a PVC tubing comprising a polymeric plasticizer and/or a high molecular weight plasticizer having a molecular weight of 540 g/mol or more. The fluid flow circuit assembly also comprises a medical device component comprising a bond surface to which the PVC tubing is bonded by a solvent, wherein the bond surface comprises a polyester elastomer, plasticized PVC, and/or a polycarbonate.

A fluid flow circuit assembly for a biological fluid processing device, comprising a PVC tubing comprising a polymeric plasticizer and/or a high molecular weight plasticizer having a molecular weight of 540 g/mol or more. The fluid flow circuit assembly also comprises a medical device component comprising a bond surface to which the PVC tubing is bonded by a solvent, wherein the bond surface comprises a polyester elastomer, plasticized PVC, and/or a polycarbonate.

Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

A medical device, such as a dilatation balloon, including plasticized nylon, and plasticized nylon.