The present invention relates to a coating for a device, wherein the coating comprises a polymeric film, wherein the polymeric film comprises a polymerisation product formed from a polymerisation solution comprising dopamine, or a salt thereof, and at least one amino acid, or a salt thereof; and a metallic layer formed on the polymeric film.

Embodiments provided herein include methods, compositions, and uses of aromatic alcohols to increase the potency of antifungal agents.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

An antimicrobial coating is formed from a biocompatible flexible polymer having incorporated therein an active material having a reducible form of silver, where at least a portion of the active material is exposed at the surface of the polymer. The coating can be applied to the surface of a catheter to inhibit bacterial growth and biofilm formation.

An antimicrobial coating is formed from a biocompatible flexible polymer having incorporated therein an active material having a reducible form of silver, where at least a portion of the active material is exposed at the surface of the polymer. The coating can be applied to the surface of a catheter to inhibit bacterial growth and biofilm formation.

This application disclosed a balloon device, comprising: a balloon catheter, and a balloon arranged on the balloon catheter, the balloon has a front end portion and a rear end portion in a longitudinal direction, and a pharmaceutical composition is provided on an outer surface of at least one of the front end portion and the rear end portion. The end drug coated balloon disclosed in this application combined with the existing instruments to treat the fistula can realize the continuous opening of the atrial septal fistula, prevent the atrial septal fistula from closing naturally in a short time, and achieve the effect of reducing cardiac preload and treating heart failure in a long time.

This application disclosed a balloon device, comprising: a balloon catheter, and a balloon arranged on the balloon catheter, the balloon has a front end portion and a rear end portion in a longitudinal direction, and a pharmaceutical composition is provided on an outer surface of at least one of the front end portion and the rear end portion. The end drug coated balloon disclosed in this application combined with the existing instruments to treat the fistula can realize the continuous opening of the atrial septal fistula, prevent the atrial septal fistula from closing naturally in a short time, and achieve the effect of reducing cardiac preload and treating heart failure in a long time.

Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising thermolysin.

Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising thermolysin.