A preparation method comprises following steps: S1: dissolving a coupling agent in an ethanol solution, adding an ultrafine radiopaque agent powder in the ethanol solution, and obtaining a modified ultrafine radiopaque agent powder by agitation, washing and drying, the ultrafine radiopaque agent powder having a particle size of 0.35-0.8 μm; S2: obtaining the radiopaque material by mixing a medical polymeric material with the modified ultrafine radiopaque agent powder. A prepared radiopaque material exhibits not only radiopaque functions but also good mechanical properties of improved elastic modulus, fracture strength and bending modulus, thereby expanding application of medical polymer hollow fibers in high-end medical products for minimally invasive intervention. Particularly, delivery devices applied with prepared radiopaque material have improved pushing and torque performance and are suitable for ultra-smooth guidewires, heart valve prostheses, guiding catheters, and degradable balloons.

A preparation method comprises following steps: S1: dissolving a coupling agent in an ethanol solution, adding an ultrafine radiopaque agent powder in the ethanol solution, and obtaining a modified ultrafine radiopaque agent powder by agitation, washing and drying, the ultrafine radiopaque agent powder having a particle size of 0.35-0.8 μm; S2: obtaining the radiopaque material by mixing a medical polymeric material with the modified ultrafine radiopaque agent powder. A prepared radiopaque material exhibits not only radiopaque functions but also good mechanical properties of improved elastic modulus, fracture strength and bending modulus, thereby expanding application of medical polymer hollow fibers in high-end medical products for minimally invasive intervention. Particularly, delivery devices applied with prepared radiopaque material have improved pushing and torque performance and are suitable for ultra-smooth guidewires, heart valve prostheses, guiding catheters, and degradable balloons.

The invention relates to a rod-shaped body comprised of one or more filaments and of a non-ferromagnetic matrix material. The matrix material surrounds the filament(s) and/or adheres them to one another. The rod-shaped body is also comprised of a dopant consisting of particles that generate magnetic resonance tomographic artifacts that is introduced into the matrix material. Rod-shaped bodies of this type can be used to construct guide wires, catheters and other instruments to be used in minimally invasive surgical interventions.

The invention relates to a rod-shaped body comprised of one or more filaments and of a non-ferromagnetic matrix material. The matrix material surrounds the filament(s) and/or adheres them to one another. The rod-shaped body is also comprised of a dopant consisting of particles that generate magnetic resonance tomographic artifacts that is introduced into the matrix material. Rod-shaped bodies of this type can be used to construct guide wires, catheters and other instruments to be used in minimally invasive surgical interventions.

Aspects of the invention relate to composite markers that employ a gel carrier to carry two or more contrast materials, each detectable by a detection modality different than one another. Kits and methods for forming these composite markers and methods of marking a target site in a mammalian subject employing these composite markers are also discussed herein.

A radiopaque structure and an implanted medical instrument having the radiopaque structure. The radiopaque structure includes at least one radiopaque unit, and each radiopaque unit includes at least one radiopaque object. In at least one incidence direction of a light source, all the radiopaque objects in the radiopaque structure are divided into n regions according to the thickness in the incidence direction, and a projection area Sm of m regions of the n regions and an effective thickness dm of the m regions meet Sm−0.0136(dm)a≥0, wherein −0.95≤a≤−0.85 and 1≤m≤n. The radiopaque structure has good or excellent visibility.

A radiopaque structure and an implanted medical instrument having the radiopaque structure. The radiopaque structure includes at least one radiopaque unit, and each radiopaque unit includes at least one radiopaque object. In at least one incidence direction of a light source, all the radiopaque objects in the radiopaque structure are divided into n regions according to the thickness in the incidence direction, and a projection area Sm of m regions of the n regions and an effective thickness dm of the m regions meet Sm−0.0136(dm)a≥0, wherein −0.95≤a≤−0.85 and 1≤m≤n. The radiopaque structure has good or excellent visibility.

The embodiments described herein relate to a self-positioning, quick-deployment low profile transvenous electrode system for sequentially pacing both the atrium and ventricle of the heart in the dual chamber mode, and methods for deploying the same.

The embodiments described herein relate to a self-positioning, quick-deployment low profile transvenous electrode system for sequentially pacing both the atrium and ventricle of the heart in the dual chamber mode, and methods for deploying the same.

Embodiments herein include delivery systems for active agent coated balloons and related methods. In an embodiment, a delivery system can include a tunneling sheath and a balloon catheter. The tunneling sheath can include a tubular shaft having an outer diameter and defining a lumen. The tunneling sheath can include a proximal collar defining a lumen. The balloon catheter can include a balloon catheter shaft disposed within the tubular shaft. The balloon catheter shaft can include a lumen for the passage of a fluid therein. The balloon catheter can include an expandable balloon disposed on the balloon catheter shaft. The balloon catheter shaft can include an active agent layer disposed on the expandable balloon. The position of the expandable balloon can be configured to be stationary relative to the tubular shaft as the delivery system is passed through a blood vessel of a patient. Other embodiments are also included herein.