A patient-specific drill template for spine screw placement includes a hook-shaped main body, and an insertion guiding portion that guides a spine screw to be inserted into a vertebra. The main body includes a tight contact portion and a hook portion, the tight contact portion connecting with insertion guiding portion, the hook portion extending from the tight contact portion, and the main body partially surrounds the vertebra. A method of preparing a patient-specific drill template for spine screw placement includes preparing a three-dimensional computed tomography of a lumbar or thoracic spine in a hospital; transferring the CT data to the manufacturing facility using a network; processing the computed tomography to generate a three-dimensional reconstruction template of the patient-specific drill template in the facility; preparing the patient-specific drill template based on the reconstruction template; packaging the template and sterilizing the patient-specific drill template.

Magnesium alloy containing, in % by mass, 1.0 to 2.0% of Zn, 0.05 to 0.80% by mass of Zr, 0.05 to 0.40% by mass of Mn, and the balance consisting of Mg and unavoidable impurities. The magnesium alloy may further contain, in % by mass, 0.005% or more and less than 0.20% of Ca.

The invention relates to compositions including magnesium-lithium alloys containing various alloying elements suitable for medical implant devices. The devices may be constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also relates to methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, such as but not limited to, orthopedic, dental, craniofacial and cardiovascular surgery.

Thin-film mesh for medical devices, including stent and scaffold devices, and related methods are provided. Micropatterned thin-film mesh, such as thin-film Nitinol (TFN) mesh, may be fabricated via sputter deposition on a micropatterned wafer. The thin-film mesh may include slits to be expanded into pores, and the expanded thin-film mesh used as a cover for a stent device. The stent device may include two stent modules that may be implanted at a bifurcated aneurysm such that one module passes through a medial surface of the other module. The thin-film mesh may include pores with complex, fractal, or fractal-like shapes. The thin-film mesh may be used as a scaffold for a scaffold device. The thin-film scaffold may be placed in a solution including structural protein such as fibrin, seeded with cells, and placed in the body to replace or repair tissue.

The present invention concerns a process for the production of implants with an ultrahydrophilic surface as well as the implants produced in that way and also processes for the production of loaded, so-called bioactive implant surfaces of metallic or ceramic materials, which are used for implants such as artificial bones, joints, dental implants or also very small implants, for example what are referred to as stents, as well as implants which are further produced in accordance with the processes and which as so-called “delivery devices” allow controlled liberation, for example by way of dissociation, of the bioactive molecules from the implant materials.

A medical device includes a base layer, and a lubrication layer supported on at least a part of the base layer, wherein the lubrication layer contains a block copolymer (A) composed of a first constituting unit derived from a reactive monomer that has an epoxy group and a second constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, and a polymer (B) composed of a constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, wherein the block copolymer (A) is contained in a proportion of 20 to 80% by weight relative to the total weight of the block copolymer (A) and the polymer (B), and wherein the block copolymer (A) is crosslinked or polymerized to form a mesh structure.

Methods and devices are provided for the use of thin-film cuffs on endovascular grafts. A method includes forming a fenestrated thin-film Nitinol sheet, expanding the fenestrated thin-film Nitinol sheet to expand the fenestrations, and attaching the expanded thin-film Nitinol sheet to a longitudinal end of a cover for an endovascular graft to form a cuff for the endovascular graft. The method may further include implanting the endovascular graft into a blood vessel. An endovascular graft may include a cover having a proximal and distal end, a proximal thin-film mesh cuff extending from the proximal end, and a distal thin-film mesh cuff extending form the distal end.

Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices are described.

Provided is a super elastic alloy for biological use having a high biocompatibility, good processability and super elasticity, said super elastic alloy being a super elastic zirconium alloy for biological use comprising 27-54 mol % inclusive of titanium, 5-9 mol % inclusive of niobium which is a β phase-stabilizing element capable of stabilizing the β phase of zirconium, and 1-4 mol % inclusive in total of tin and/or aluminum which are ω phase-suppressing elements capable of suppressing the ω phase of zirconium, with the balance consisting of zirconium and inevitable impurities.

An embodiment of the invention relates to a cobalt-based alloy, which due to the composition exhibits twinning as the dominating deformation mechanism: Cr: 13.0 to 30.0% by weight Mn: 2.0 to 10.0% by weight W: 2.0 to 18.0% by weight Fe: 5.0 to 15.0% by weight C: 0.002 to 0.5% by weight N: 0 to 0.2% by weight Si: 0 to 2.0% by weight Ni: 0 to 5.0% by weight
wherein the aforementioned alloying components and manufacturing-related impurities add up to 100% by weight, and the following restrictions according to formulas (1) and (2) apply to the contents of nitrogen and carbon, and the following restrictions according to formula (3) apply to the contents of oxygen, phosphorus and sulfur:
0.003%≦C+N≦0.5% weight  (1)
N/C(wt. %)≦1.00 for 0.07%<C<0.15% (weight)  (2)
O+P+S<0.10% weight  (3).