An in-vivo implantable electronic device includes a housing, a power reception coil, and an electronic circuit. The housing is formed of a biocompatible material and forms an internal space sealed. The power reception coil is disposed in the internal space of the housing and receives power by interacting with an electromagnetic field formed by an external electric field or magnetic field, or transmits an electromagnetic wave to the outside. The electronic circuit is disposed in the internal space, is connected to the power reception coil, and performs at least processing of an electric signal. The housing includes a first member in a box shape formed of a biocompatible metal material and having an opening, a second member formed of a biocompatible nonmetal material and having a shape that closes the opening, a packing in an annular shape disposed between the first member and the second member.

Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.

Two-dimensional materials can be formed into enclosures for various substances and a substrate layer can be provided on an outside and/or on an inside of the enclosure, wherein the enclosure is not cytotoxic. The enclosures can be exposed to an environment, such as a biological environment (in vivo or in vitro), where the fibrous layer can promote vascular ingrowth. One or more substances within the enclosure can be released into the environment, one or more selected substances from the environment can enter the enclosure, one or more selected substances from the environment can be prevented from entering the enclosure, one or more selected substances can be retained within the enclosure, or combinations thereof. The enclosure can, for example, allow a sense-response paradigm to be realized. The enclosure can, for example, provide immunoisolation for materials, such as living cells, retained therein.

An air-permeable guard adapted to attach to a covering, the air permeable guard comprising a plurality of layers attached together to create one or more compartments. The guard further comprises at least one agent stored in the one or more compartments wherein the at least one agent may be a counteracting agent, a masking agent or a disinfectant agent. The masking agent may be coffee, oil and self encapsulated oil beadlet. The counteracting agent may be activated charcoal, sodium bicarbonate, zeolite, diatomaceous earth, silica gel and bentonite clay. The disinfectant agent may be a water based coating containing a cationic siloxane. In another embodiment of the invention the compartments may store the agents in a portion of the guard that is adapted to come in contact with the wearer's nostrils.

Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.

Some embodiments are directed to a cellulite treatment system that contains a laser generating device. A hydrogel patch may include a region, at a first side of the hydrogel patch, to be in contact with a person's skin. The region may contain an adsorbing medium (e.g., carbon black or any other substance that would have a similar effect) that, when receiving a laser beam from the laser generating device, results in Extracorporeal Shock Wave Therapy (ESWT) being applied to the person's skin to treat cellulite.

Some embodiments are directed to a cellulite treatment system that contains a laser generating device. A hydrogel patch may include a region, at a first side of the hydrogel patch, to be in contact with a person's skin. The region may contain an adsorbing medium (e.g., carbon black or any other substance that would have a similar effect) that, when receiving a laser beam from the laser generating device, results in Extracorporeal Shock Wave Therapy (ESWT) being applied to the person's skin to treat cellulite.

A micro-needle (MN) patch is formed as an array of 3-D bioprinted structures having a relatively hard planar base with multiple water sensitive barbed tips extending therefrom. The barbed tips are formed from a polymer material configured to exhibit reversible shrink-swell volume change in response to surrounding humidity to facilitate skin penetration under the shrinkage conditions and long-term adhesion when swelling in skin tissues.

Implementations of a wearable physical characteristic monitoring (PCM) device can include a substrate including two or more electrical traces, the two or more electrical traces being formed as laser-induced graphene (LIG) in a starch-based material layer, a sensor that provides a signal responsive to physiological characteristics of a patient wearing the PCM device, a processing system that provides physiological characteristics data based on the signal, and a communications system that enables communication of the physiological characteristics data from the PCM device, wherein the two or more electrical traces connect one or more of the sensor, the processing system, and the communications system.

The present invention provides a piezoelectric conductive composite stent and a preparation method thereof, the length of the piezoelectric conductive composite stent is 1 cm-3 cm, the inner diameter of the piezoelectric conductive composite stent is 2.5 mm-3.5 mm, and the thickness of the pipe wall of the piezoelectric conductive composite stent is 0.4 mm-0.45 mm. The piezoelectric conductive composite stent comprises: an inner layer and an outer layer sleeved outside the inner layer, and a plurality of nano grooves are provided in the peripheral face of the outer layer; wherein, the inner layer is prepared from polycaprolactone dissolved in a binary organic solvent; the outer layer is prepared from at least one of the polycaprolactone dissolved in a binary organic solvent, polyvinylpyrrolidone dissolved in a binary organic solvent, nanoparticles of metal organic framework materials, or nanoparticles of graphene or its derivatives.