A tumor ablation system includes a heating needle and a power supply device. The heating needle includes a rigid tubular shell. The heating needle further includes a heating element and a non-heating element; the heating element has at least one heating wire, a central cylindrical object and a distal part of the shell. The heating wire and the central cylindrical object are inside the shell. The heating wire is electrically coupled to the non-heating element, and coiled on the central cylindrical object. The distal part of the shell covers the coil formed by the heating wire on the central cylindrical object. When the heating wire is charged with electricity the heating wire generates thermal energy that is conducted to the distal part of the shell. The power supply device couples to the non-heating element, and provides electricity to the heating needle.

Systems and methods for imaging an object that are capable of capturing an image or images of the object using an imaging modality, automatically detecting and analyzing the image or images by way of converting the image or images to at least one binary image, and analyzing the at least one binary image to extract and/or segment regions-of-interest (ROIs) from the at least one binary image. The object can be or include an implantation, occlusion, medical device, body lumen, tissue, organ, duct, and/or vessel. The imaging modality can be or include X-ray, CT, MRI, PET, and/or ultrasound, or any combination thereof. Also included are compositions of soft, implantable materials with one or more carbon-based material, nanomaterial, and/or allotrope present in an amount sufficient as an ultrasound contrast agent effective for days, months, or years and which compositions are useful in the automated imaging methods of the invention.

Anatomically accurate brain phantoms are disclosed which may be patient specific and used for experimentally testing neuromodulation and neuroimaging procedures.

The present invention concerns a thermal drawing method for forming fibers, wherein said fibers are made at least from a stretchable polymer. The present invention also concerns drawn fibers made by the process.

A medical injection needle (1) having a metallic needle body (2) comprising an axially extending wall (3), a first end portion (4), a second end portion (6), and a flow path (7) providing for fluid communication between the first end portion (4) and the second end portion (6) along the axially extending wall (3), wherein at least a portion of the metallic needle body (2) comprises a hardened surface layer (10, 20) in which carbon atoms and nitrogen atoms are deposited.

The present invention relates to a method for making a three dimensional carbon structure and also to a sintered article comprising pyrolyzed carbon particles. The method comprises sintering a powdered organic material, preferably using selective laser sintering, to form a sintered three dimensional structure having a desired shape. The sintered structure is then pyrolyzed to form the final carbon structure. The method is particularly useful in the production of biomedical implants such as bone scaffolds and joint replacements. In some embodiments, the powdered organic material is lignin which provides a renewable and highly cost effective starting material for the method of the present invention.

The present invention relates to a method for making a three dimensional carbon structure and also to a sintered article comprising pyrolysed carbon particles. The method comprises sintering a powdered organic material, preferably using selective laser sintering, to form a sintered three dimensional structure having a desired shape. The sintered structure is then pyrolysed to form the final carbon structure. The method is particularly useful in the production of biomedical implants such as bone scaffolds and joint replacements. In some embodiments, the powdered organic material is lignin which provides a renewable and highly cost effective starting material for the method of the present invention.

Embodiments herein relate to chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is included having a graphene varactor including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through non-covalent interactions between the self-assembled monolayer and a ?-electron system of graphene. The self-assembled monolayer includes one or more pillarenes, substituted pillarenes, calixarenes, substituted calixarenes, peralkylated cyclodextrins, substituted peralkylated cyclodextrins, pyrenes, or substituted pyrenes, or derivatives thereof. Other embodiments are also included herein.

Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.

A moldable sheet comprising malleable strands arranged in a substantially flat or planar configuration. The moldable sheet can be manipulated into a variety of shapes and is capable of maintaining the manipulated shape. Broken and fractured bones and bone fragments can be held together by wrapping a moldable sheet around the exterior of the break or fracture area. The moldable sheet can secure the ends of the bone for healing and can be incorporated into the new bone growth. The structure of the moldable sheet can be such that electromagnetic waves, such as those used with medical or security scanning equipment, are able to pass through pores in the device. This can make the moldable sheet radiolucent.