A medical device that is at least partially formed of a refractory metal alloy, and a method for inserting the medical device in a patient.

A medical device that is at least partially formed of a refractory metal alloy, and a method for inserting the medical device in a patient.

A method of manufacturing a covered stent is disclosed. The method includes winding a first PTFE tape around a cylinder body of a jig, winding a second PTFE tape around a stent including the jig fitted therein, heating the stent in an oven, fitting the stent into upper and lower elastic members, fitting the elastic members into a mold, pressing the upper elastic member to bond the PTFE tapes to each other and to thus form a first film at a cylindrical body of the stent, taking the elastic members out of the mold, taking the stent out of the elastic members, removing the jig from the stent, forming a silicone coating layer at an expansion portion of the stent, and sewing the spaces in the expansion portion, the second PTFE tape, and the silicone coating layer to form a second film at the expansion portion.

A method of manufacturing a covered stent is disclosed. The method includes winding a first PTFE tape around a cylinder body of a jig, winding a second PTFE tape around a stent including the jig fitted therein, heating the stent in an oven, fitting the stent into upper and lower elastic members, fitting the elastic members into a mold, pressing the upper elastic member to bond the PTFE tapes to each other and to thus form a first film at a cylindrical body of the stent, taking the elastic members out of the mold, taking the stent out of the elastic members, removing the jig from the stent, forming a silicone coating layer at an expansion portion of the stent, and sewing the spaces in the expansion portion, the second PTFE tape, and the silicone coating layer to form a second film at the expansion portion.

A method of manufacturing a covered stent is disclosed. The method includes winding a first PTFE tape around a cylinder body of a jig, winding a second PTFE tape around a stent including the jig fitted therein, heating the stent in an oven, fitting the stent into upper and lower elastic members, fitting the elastic members into a mold, pressing the upper elastic member to bond the PTFE tapes to each other and to thus form a first film at a cylindrical body of the stent, taking the elastic members out of the mold, taking the stent out of the elastic members, removing the jig from the stent, forming a silicone coating layer at an expansion portion of the stent, and sewing the spaces in the expansion portion, the second PTFE tape, and the silicone coating layer to form a second film at the expansion portion.

The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

Compositions are provided according to aspects of the present invention that include a hydrogel and a liner, wherein a surface of the hydrogel dissociably-engages a surface of the liner. Compositions are provided according to aspects of the present invention that include a hydrogel and a hydrophobic glue, wherein at least a portion of the gel network of the hydrogel is occupied by the hydrophobic glue. Reverse coaling processes and articles of manufacture made by reverse coating processes are provided according to aspects of the present invention. Compositions are provided according to aspects of the present invention that include a hydrogel and a substrate, wherein: the hydrogel comprises a polymer network; the substrate comprises a surface comprising a polymer network; and the polymer network of the hydrogel and the polymer network of the surface are entangled.

Compositions are provided according to aspects of the present invention that include a hydrogel and a liner, wherein a surface of the hydrogel dissociably-engages a surface of the liner. Compositions are provided according to aspects of the present invention that include a hydrogel and a hydrophobic glue, wherein at least a portion of the gel network of the hydrogel is occupied by the hydrophobic glue. Reverse coaling processes and articles of manufacture made by reverse coating processes are provided according to aspects of the present invention. Compositions are provided according to aspects of the present invention that include a hydrogel and a substrate, wherein: the hydrogel comprises a polymer network; the substrate comprises a surface comprising a polymer network; and the polymer network of the hydrogel and the polymer network of the surface are entangled.