A surgical staple comprising a substrate and one or more coatings which slows the bioabsorption of the substrate. The coating can be selected so as to affect the environment surrounding the staple once the staple is implanted in the patient. The effect on the environment can cause the bioabsorption to occur within a desired time frame.

A surgical staple comprising a substrate and one or more coatings which slows the bioabsorption of the substrate. The coating can be selected so as to affect the environment surrounding the staple once the staple is implanted in the patient. The effect on the environment can cause the bioabsorption to occur within a desired time frame.

A surgical staple comprising a substrate and one or more coatings which slows the bioabsorption of the substrate. The coating can be selected so as to affect the environment surrounding the staple once the staple is implanted in the patient. The effect on the environment can cause the bioabsorption to occur within a desired time frame.

A method for production of anti-microbial orthodontic elastomeric ligatures is disclosed. The elastomeric ligatures are coated with an anti-microbial solution layer by layer. The coating solution comprising an anti-bacterial agent, a polymer and a solvent in the following ratio: 2 g anti-microbial agent, 4 g polymer and 200 mL solvent. The hypo-allergic latex-free orthodontic elastomeric ligatures with an internal diameter of 0.045 inches and external diameter of 0.115 inches are rinsed in distilled water, dried at 60° C. and sprayed with the anti-bacterial solution two times and dried for five minute. This process is repeated for five times and the elastomeric ligatures are dried at room temperature for 1 h.

A method for production of anti-microbial orthodontic elastomeric ligatures is disclosed. The elastomeric ligatures are coated with an anti-microbial solution layer by layer. The coating solution comprising an anti-bacterial agent, a polymer and a solvent in the following ratio: 2 g anti-microbial agent, 4 g polymer and 200 mL solvent. The hypo-allergic latex-free orthodontic elastomeric ligatures with an internal diameter of 0.045 inches and external diameter of 0.115 inches are rinsed in distilled water, dried at 60° C. and sprayed with the anti-bacterial solution two times and dried for five minute. This process is repeated for five times and the elastomeric ligatures are dried at room temperature for 1 h.

Disclosed herein are medical products, including an implantable device coated with a crosslinked extracellular matrix comprising at least one of Type IV collagen and laminin, wherein the crosslinked extracellular matrix contains no more than 0.024 mg/ml total concentration of glucose, amino acids and salts having a molecular weight of 2000 daltons or less. Corresponding systems and method also are disclosed.

Disclosed herein are medical products, including an implantable device coated with a crosslinked extracellular matrix comprising at least one of Type IV collagen and laminin, wherein the crosslinked extracellular matrix contains no more than 0.024 mg/ml total concentration of glucose, amino acids and salts having a molecular weight of 2000 daltons or less. Corresponding systems and method also are disclosed.

Disclosed herein are medical products, including an implantable device coated with a crosslinked extracellular matrix comprising at least one of Type IV collagen and laminin, wherein the crosslinked extracellular matrix contains no more than 0.024 mg/ml total concentration of glucose, amino acids and salts having a molecular weight of 2000 daltons or less. Corresponding systems and method also are disclosed.

A medical implant comprising a plurality of layers, each layer comprising a polymer and a plurality of uni-directionally aligned continuous reinforcement fibers.

A medical implant comprising a plurality of layers, each layer comprising a polymer and a plurality of uni-directionally aligned continuous reinforcement fibers.