Described are medical devices including expandable tubular bodies configured to be implanted into a lumen, wherein the outer surface of the expandable tubular bodies are coupled to a polymer(s).

Described are medical devices including expandable tubular bodies configured to be implanted into a lumen, wherein the outer surface of the expandable tubular bodies are coupled to a polymer(s).

Described are medical devices including expandable tubular bodies configured to be implanted into a lumen, wherein the outer surface of the expandable tubular bodies are coupled to a polymer(s).

The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

The present disclosure relates to medical devices, and methods for producing and using the devices. In embodiments, the medical device may be a buttress including a porous substrate possessing a therapeutic layer of a chemotherapeutic agent and optional excipient(s) thereon. By varying the form of chemotherapeutic agents and excipients, the medical devices may be used to treat both the area to which the medical device is attached as well as tissue at a distance therefrom.

The present invention provides a surgical anchor comprising a screw and a coil; said coil having a conical shape, wound around the screw shaft with the first end of the coil being tapered and having a ring circumference smaller than that of the screw head and being engaged to the bottom of the screw head and the second end of the coil being flared with a larger ring circumference and positioned along the screw shaft.

The present invention provides a surgical anchor comprising a screw and a coil; said coil having a conical shape, wound around the screw shaft with the first end of the coil being tapered and having a ring circumference smaller than that of the screw head and being engaged to the bottom of the screw head and the second end of the coil being flared with a larger ring circumference and positioned along the screw shaft.

Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

The present invention relates to a method for preparation of a functionalized surface comprising the steps: a) coating of a carrier with a least one polymer selected from a polyanionic or polycationic polymer, b) addition of at least one compound to the coated carrier of step a), c) exposing the at least one polyanionic or polycationic polymer on the coated carrier of step b) to an organic solvent, resulting in compaction of the at least one polyanionic or polycationic polymer and thereby encapsulating the at least one compound, d) reversible cross-linking of the at least one polyanionic or polycationic polymer of step c) with at least one cross-linker; e) removal of the organic solvent. Furthermore, the invention relates to a functionalized surface, a functionalized surface for use in medicine and a method for releasing a compound ex vivo.