Described herein is a method of coating a prosthetic device, such as an ocular prosthetic device, the method comprising nanoelectrospraying droplets comprising an active ingredient and/or a carrier species onto a surface of the prosthetic device in a predetermined pattern, the nanoelectrospraying involving controlling the flow rate of the droplets from a nozzle of the nanoelectrospraying equipment by controlling the voltage between the nozzle and the ocular prosthetic device. Also described herein are ocular prosthetic device formable according to the method.

A parent artery occlusion (PAO) device which provides for immediate occlusion of a cerebral artery to isolate a defect. The PAO device includes a self-expanding wire-frame prolate structure which is partially covered with an ePTFE membrane.

A parent artery occlusion (PAO) device which provides for immediate occlusion of a cerebral artery to isolate a defect. The PAO device includes a self-expanding wire-frame prolate structure which is partially covered with an ePTFE membrane.

A parent artery occlusion (PAO) device which provides for immediate occlusion of a cerebral artery to isolate a defect. The PAO device includes a self-expanding wire-frame prolate structure which is partially covered with an ePTFE membrane.

In various embodiments, a tissue thickness compensator can comprise one or more capsules and/or pockets comprising at least one medicament therein. In at least one embodiment, staples can be fired through the tissue thickness compensator to rupture the capsules. In certain embodiments, a firing member, or knife, can be advanced through the tissue thickness compensator to rupture the capsules.

A method of using an implantable device provides an implantable device including a plurality of links (113, 115, 117, 119), a device closure pin (111), a lock-in unit (103) attached and located between two links, and a quick release unit (105) attached and located between two links. The plurality of links (113, 115, 117, 119), lock-in unit (103) and release unit (105) are constructed in a closed contour. The closed contour of the implantable device, in a rigid state (151), is a figure eight comprised of two arcs (125, 127) and two connected interconnecting sections (131, 133).

A method of using an implantable device provides an implantable device including a plurality of links (113, 115, 117, 119), a device closure pin (111), a lock-in unit (103) attached and located between two links, and a quick release unit (105) attached and located between two links. The plurality of links (113, 115, 117, 119), lock-in unit (103) and release unit (105) are constructed in a closed contour. The closed contour of the implantable device, in a rigid state (151), is a figure eight comprised of two arcs (125, 127) and two connected interconnecting sections (131, 133).

An ultrasonic surgical blade includes a body having a proximal end, a distal end, and an outer surface. The distal end is movable relative to a longitudinal axis in accordance with ultrasonic vibrations applied to the proximal end. At least a portion of the outer surface of the body comprises a lubricious coating adhered thereto. The lubricious coating has a coefficient of friction that is less than the coefficient of friction of the outer surface of the body.

An ultrasonic surgical blade includes a body having a proximal end, a distal end, and an outer surface. The distal end is movable relative to a longitudinal axis in accordance with ultrasonic vibrations applied to the proximal end. At least a portion of the outer surface of the body comprises a lubricious coating adhered thereto. The lubricious coating has a coefficient of friction that is less than the coefficient of friction of the outer surface of the body.

Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.