A system may receive a package previously irradiated for sterilization. The package may have a sensor comprising a reference tag and sensing tag at least partially coated with a material comprising poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) and Polyurethan (PU). The system may scan the sensing tag and the reference tag. The system may determine, based on radio frequency (RF) signals reflected from the sensing tag and reference tag, the sensor is exposed to radiation. The system may output a quality measure indicative of the sensor being exposed to radiation.

The present disclosure relates to a system for the thermally controlled processing of biological material in a liquid sample in a multiwell plate using magnetic particles. Also disclosed is a corresponding method for the thermally controlled processing of biological material in a liquid sample.

The present invention is directed to a process of manufacturing a pharmaceutical composition, a pharmaceutical composition produced by the process of the present invention and a container comprising a pharmaceutical composition produced by the process of the present invention.

A method of sterilizing an article such as a flexible endoscope is performed in a sterilization chamber. A vacuum is applied in the sterilization chamber while the article is contained in the sterilization chamber. A sterilant is then introduced into the sterilization chamber. The pressure within the sterilization chamber is incrementally increased to provide a step-wise transition from a high vacuum state to atmospheric pressure. The article is thereby sterilized.

A method of producing a ready-to-use medical device with a functional coating includes the steps of bringing the medical device, at least with its functional coating, in contact with a composition which prevents or retards degradation of the functional coating and sterilizing the medical device and the composition via radiation. A method leads to an improved product, namely an improved ready-to-use medical device which does not suffer a loss of quality during sterilization and storage. The composition comprises carboxymethyl cellulose or a derivative or salt thereof and/or an antioxidant selected from gallic acid or a derivative thereof.

A package for an object including a support element with a first chamber containing the object and a coupler configured to hold the object suspended through the coupler so that the object extends into a space left free between the coupler and a bottom portion of the support element. A stopper is coupled to the support element of the object, such that the support element presents a grip portion that projects from the stopper. A cover is coupled to the stopper, so as to co-operate with the stopper to define a second chamber inside which the grip portion of the support element extends. While the cover is coupled to the stopper, a grip portion of the stopper projects from the cover. While the bottom portion of the support element is coupled to the stopper, the length of the object remains visible.

A method of sterilizing an article such as a flexible endoscope is performed in a sterilization chamber. A vacuum is applied in the sterilization chamber while the article is contained in the sterilization chamber. A sterilant is then introduced into the sterilization chamber. The pressure within the sterilization chamber is incrementally increased to provide a step-wise transition from a high vacuum state to atmospheric pressure. The article is thereby sterilized.

A first alternative to a composition for preventing or retarding degradation of a functional coating on a medical device includes an antioxidant selected from gallic acid or a derivative thereof. A second alternative to a composition for preventing or retarding degradation of a functional coating on a medical device includes carboxymethyl cellulose or a derivative or salt thereof. The use of the compositions for preventing or retarding degradation of a functional coating on a medical device from reactive species generated during exposure of radiation, and a wetting agent comprising the compositions, are also provided. The wetting agent prevents or retards the hydrolytic degradation of the coating during the intended shelf-life of the wetted coated product.

A device and method for cleaning a target may include supporting a target on a support in a chamber in a housing, the chamber optionally defined by at least one UV reflective plate; operating at least one UV emitter attached to the housing and positioned to emit UV radiation into the chamber so that the UV radiation illuminates the target; and operating an actuator to modify the UV radiation illumination of the target while the UV emitter is operated.

A decontamination system for a device, such as a lumen device, is provided. The decontamination system includes a terminal package defining a device receiving area. The terminal package includes a fluid inlet through which sterilant fluid can be delivered to the device receiving area. An accumulator apparatus is provided that is configured to switch between trapping sterilant fluid delivered into the device receiving area and delivering sterilant fluid to the device receiving area based on pressure changes in the device receiving area. \y 700