A61L2202/21

Biocompatible molded part
11229723 · 2022-01-25 ·

The invention relates to a biocompatible molded part for supporting new bone formation, in particular the reformation of a jaw bone or a jaw bone portion in a mammal, preferably a human, wherein the molded part is suitable to be placed on the jaw bone and is designed as a solid body. The invention also relates to a composition for producing a biocompatible molded part, a method for producing a biocompatible molded part, a use of a biocompatible molded part and a kit comprising a plurality of molded parts.

MODULAR ASEPTIC PRODUCTION SYSTEM

A modular production system including a plurality of production modules connected in a linear series to form a production tunnel, and collectively defining a production channel, and wherein at least one fluid inlet port defined along the production tunnel, said inlet port is in fluid communication with a pressurized fluid source, whereby influx of fluid from said fluid source through said fluid inlet port acts to maintain the fluid pressure within the production channel at a higher pressure than the atmospheric pressure outside of the production tunnel; and wherein one of said production modules positioned between said proximal-most and distal-most production modules comprises a depyrogenator and/or sterilization module, comprising a transparent tubular body, and an irradiation source positioned external to said transparent tubular body, said irradiation source capable of heating the internal environment of the depyrogenation and/or sterilization module to a temperature sufficient to depyrogenate or sterilize articles passing therethrough.

Device for sterilization of flexible bags and method for sterilizing flexible bags

A device is for sterilization by electron beam irradiation of flexible bags, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. A sterilization method includes irradiating flexible bags by electron beam irradiation. An in-line method for filling flexible can use the sterilization device and method.

Inactivation of pathogens in biological media

The invention relates to the processing of fluid biological media, especially of culture media or cell- or virus suspensions, potentially containing active pathogens, with the aim of inactivating these pathogens and/or modifying ingredients in these biological media by thermal or radiological treatment.

METHOD FOR DECONTAMINATING A BIOMOLECULE PRODUCTION SYSTEM AND A SYSTEM SUITABLE FOR DECONTAMINATION
20210355428 · 2021-11-18 ·

The current disclosure concerns a method for decontaminating a virus production system, wherein virus particles are produced in at least one bioreactor and purified from liquids comprising said virus particles thereby generating liquid waste, said method comprising the step of exposing said system or a part thereof to heated air and/or liquid at a temperature of at least 60° C. after viral production took place, thereby eradicating remaining virus particles in said system. In a second and third aspect the current disclosure concerns a virus production system wherein the system comprises a heating device suitable for heating air and/or liquid to a temperature of at least 60° C., and the use of such a system for the production of viruses and/or viral vaccines.

COMPOSITION COMPRISING AQUEOUS MEDIUM WITH REDUCED SIZE WATER CLUSTERS TO IMPROVE BIOAVAILABILITY OF THE AQUEOUS MEDIUM AND METHODS FOR MAKING AND USING THE COMPOSITIONS
20210353667 · 2021-11-18 ·

The invention relates to products by processes, product compositions, product formulations and product uses that are all related to reduced ultrapure water cluster sizes in an aqueous composition containing a non-H.sub.2O substance in the reduced size water clusters in order to improve bioavailability of the aqueous composition. The invention processes use higher flow rate of the blended aqueous composition from a jet openings of a nozzle inside the hollow cylinder to reduce sizes of the ultrapure water clusters in the blended aqueous composition of the non-H.sub.2O substance to less than 300 nanometers.

SELF-DISINFECTING OBJECT

The invention relates to a self-disinfecting object having a contact surface of a substrate provided for contact with a human body part, wherein the contact surface is at least regionally heatable.

INTEGRATED CONNECTOR AND DISINFECTING CAP WITH RESERVOIR
20220008709 · 2022-01-13 · ·

Connector and disinfecting cap system includes design features that can maintain disinfectant solution for multiple connector accesses and limit the exposure time of the disinfectant solution when the connector and cap system is in an open state, for example when connector is being accessed, or a closed state, for example, when connector is not being accessed. Connector and cap system can include a cap housing, which can contain an internal disinfectant reservoir, and a connector, such as an IV needleless connector, where the cap housing is attached to the connector such that the cap can pivot in one or more axes in reference to the connector.

Systems and methods for interior energy-activation from an exterior source
11173467 · 2021-11-16 · ·

A method and a system for producing a change in a medium. The method places in a vicinity of the medium at least one energy modulation agent. The method applies an initiation energy to the medium. The initiation energy interacts with the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the energy modulation agent.

STERILIZATION AND FILTRATION OF PEPTIDE COMPOSITIONS
20220001047 · 2022-01-06 ·

Methods and devices for sterilizing viscous peptide compositions which have shear thinning rheological properties at high concentrations.