A face mask for filtering air includes a face seal for providing an airtight flexible seal around the nose and mouth of a user, a support sealably attached to the face seal, wherein the support has an open area that allows for passage of incoming air and outlet valves for expelling exhaled air, a front shell for removably attaching to the support, wherein the front shell has inlet holes for allowing the incoming air to pass through the open area of the support, and a filter for filtering particulate elements from air. The filter is configured to be housed between the front shell and the support. The face seal provides a direct connection between the filter and the user.

The invention, provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

An apparatus, system, and method for contacting blood with ozone to kill microorganisms in the blood are described. The method involves injecting microbubbles of ozone containing gas into a flow of blood, preferably at a temperature of less than 12° C. The apparatus includes a blood flow conduit including a blood ozone contacting portion including a porous ozone injector.

The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.

Provided are methods for preparing pathogen-inactivated whole blood and other pathogen-inactivated blood product compositions, as well as kits and compositions related thereto.

A method and apparatus to neutralize or destroy pathogens in red blood cell concentrate (RBCC). The apparatus may include a lamp to provide ultra-violet (UV) light having a predetermined wavelength, a focusing member to focus the UV light from the lamp, a chamber assembly to receive the RBCC at a predetermined flow rate and to cause the received RBCC to be exposed to the focused UV light, and a controller. The chamber assembly may include a window and a bladder assembly. The bladder assembly may have a movable bladder portion. The controller may control movement of the bladder portion such that a space provided between the window and a surface of the bladder assembly, wherein the RBCC is caused to flow, enables the focused UV light to neutralize or destroy at least some of the pathogens in the RBCC during flow through the space.

An apparatus for the treatment of a liquid that includes a chamber having at least one inner surface, the chamber adapted for passage of a fluid therethrough. The chamber is at least 80 percent enclosed. The apparatus also includes an optional ultraviolet-transmissive tube disposed within the chamber and also adapted for the passage of the liquid therethrough. The apparatus further includes an ultraviolet lamp disposed within the chamber and, optionally, within the ultraviolet-transmissive tube. A reflective material is interposed between the chamber and the transmissive tube. The reflective material is adapted so as to reflect at least a portion of light emitted by the ultraviolet lamp, wherein the reflective material is at least 80 percent reflective.

The present disclosure relates to methods for producing large scale nanostructured material comprising carbon nanotubes. Therefore, there is disclosed a method for making nanostructured materials comprising depositing carbon nanotubes onto at least one substrate via a deposition station, wherein depositing comprises transporting molecules to the substrate from a deposition fluid, such as liquid or gas. By using a substrate that is permeable to the carrier fluid, and allowing the carrier fluid to flow through the substrate by differential pressure filtration, a nanostructured material can be formed on the substrate, which may be removed, or may act as a part of the final component.

The invention relates to a viral inactivated biological liquid or dry mixture and to its preparation. Principally, the invention relates, but is not limited, to a mixture derived from a platelet source.

A method of preparing containers for blood-derived products includes filling the blood-derived product containers with the blood-derived product, of virally inactivating the blood-derived product containers, and detecting possible defects in the blood-derived product containers. The viral inactivation is carried out by placing the blood-derived product containers in contact with steam at sub-atmospheric pressure in a chamber adapted for that purpose.