The present disclosure provides a medical adhesive and a preparation method thereof, comprising a component A and a component B: the component A comprises a cycloketene acetal compound and an oxidizing agent; the component B comprises a vinyl monomer, a cross-linking agent and a reducing agent, wherein the cycloketene acetal compound is selected from one or more of 2-methylene-1,3-dioxepane, 2-methylene-4-phenyl-1,3-dioxolane, 5,6-benzo-2-methylene-1,3-dioxepane and 4,7-dimethyl-2-methylene-1,3-dioxepane. The medical adhesive overcomes the disadvantages of conventional medical adhesives.

Disclosed is a wound dressing material comprising a substrate, about 2.5% to about 8% by weight of a bicarbonate, and a film-forming agent, the film-forming agent serving as a binder for said bicarbonate to said substrate, the film-forming agent and the bicarbonate being present in a ratio of between 1:2 and 2:1 with respect to one another. Also disclosed are a method for preparing a wound dressing material and a method for treating a wound.

The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.

Technologies for fibers with nanotechnology is disclosed. In the illustrative embodiment, a preform is 3D printed with one or more sacrificial cores and one or more hollow channels. The preform is drawn into a fiber, and one or more metal core(s) is inserted into the hollow channel during the fiber draw. The fiber is then heated, breaking up the sacrificial cores into balls through capillary action. The fiber can be etched, exposing the balls made up of the sacrificial cores. The balls can be selectively etched, exposing the metal core(s) of the fiber. Additional embodiments are disclosed.

The present invention provides an artificial skin and a preparation method thereof. The present invention takes the xenogeneic acellular dermal matrix particles as main materials, and obtains the dermis layer by three-dimensional printing technologies, and then obtains the artificial skin by combining the epidermis layer with the dermis layer. The dermis layer of artificial skin in present invention has three-dimensional porous structure, which retains main components of natural dermal matrix in composition, and imitates distributed structure at fiber bundle diameter and pore size of natural dermal matrix in structure. This kind of novel biomimetic dermal scaffolds have obvious advantages in inducing migration and regeneration of skin cells, accelerating vascularization, promoting wound healing and improving healing quality. The dermis layer of artificial skin in present invention is obtained by three-dimensional printing technologies, which has precise and controllable structure, simple preparation method and high products qualification rate.

The present disclosure provides for oxygen generating and free radical scavenging biomaterials, an article including the oxygen generating and free radical scavenging biomaterial, wound healing dressings or structures (e.g., bandage) that have the characteristic of generating oxygen and having redox modulating capabilities. In particular, the wound healing dressing can have the characteristics of being anti-inflammatory, antioxidant, and pro-healing for extended periods of time (e.g., at least 10 days, at least 30 days).

A dual double balloon catheter includes a catheter having a proximal end portion, a central portion and a distal end portion, and a secondary treatment balloon for a catheter. The catheter includes a plurality of lumens within the catheter extending from the proximal end portion, a plurality of inflatable balloons positioned in the central portion and a secondary treatment balloon communicatively associated with the distal end portion of the catheter, and the balloons and the secondary treatment balloon being communicatively connected with a corresponding one of the plurality of lumens to selectively inflate/deflate the corresponding inflatable balloon or to receive a radioactive dose or a therapeutic agent for a treatment.

In various embodiments, a layer of material can comprise a body, a proximal end portion, and a distal end portion. The proximal end portion can be releasably secured to a staple cartridge of a surgical end effector, and the distal end portion can be releasably secured to an anvil of the surgical end effector. The layer of material can comprise a tissue thickness compensator.

The present invention relates to methods for producing biphasic calcium phosphate materials using chemical processing methods including exposure to peroxides. The resulting materials exhibit an osteoinductive needle-like surface morphology and are useful as artificial bone grafts.

A crystal of a calcium phosphate that is any one selected from the group consisting of octacalcium phosphate, hydroxyapatite, fluorapatite, chlorapatite and carbonate apatite, in which a part of a plurality of calcium ions in a crystal structure of the crystal are replaced with a silver ion or a copper ion.