Provided is a dual light-responsive zinc oxide, in the preparation process of zinc oxide, sodium citrate and hydroxypropyl methyl cellulose are added to control the morphology, photothermal conversion materials are added to make zinc oxide have photothermal conversion ability, and lignin is added to reduce the energy band gap of zinc oxide; and the hydrothermal products after lyophilization are carbonized by microwave irradiation so as to further reduce the energy band gap. The dual light-responsive zinc oxide has a Tremella-like fold structure, has dual response to yellow light and near-infrared light, has excellent adsorbability, antibacterial property and photothermal stability, and has photothermal conversion ability. The dual light-responsive zinc oxide coating has both antibacterial and osteogenic properties, which can efficiently improve the antibacterial and osteogenic capability of implants when being applied on the surface of the implants; and its special photosensitive property helps to realize the photocontrol working and on-demand action of the antibacterial and osteogenic functions of the implant.

A latex or natural rubber composition or formulation, latex or rubber products made using the same, and methods of preparing a vulcanized rubber and latex or natural rubber products are disclosed. The composition/formulation includes latex or natural rubber, 0.1-5 phr of a vulcanization activator, and 0.5-10 phr of one or more accelerators and/or additional activators. At least one accelerator and/or additional activator is a nanocomposite zinc oxide. The method includes. mixing a source of the latex or rubber with a vulcanization activator and one or more nanocomposite zinc oxides in a tank or vessel to form a latex or rubber formulation, dipping or at least partially immersing one or more molds or formers in the latex or rubber formulation to form a latex or rubber coating thereon, and curing the latex or rubber coating to vulcanize the latex or rubber coating. The vulcanized latex product is strong and has antimicrobial properties.

Anti-biofilm osseointegrating and/or tissue-integrating implantable biomaterial devices that optionally can elute therapeutic ions such as magnesium, silver, copper and/or zinc. In certain embodiments, the devices are engineered to produce structures suitable as implants having a relatively high surface population of zeolite. Methods of producing the devices are also disclosed.

The invention concerns the use of an antimicrobial composition comprising metallic silver and metallic ruthenium as well as at least one vitamin or at least one vitamin derivative for the topical treatment or prevention of skin, skin adnexa or mucosa diseases which are caused by infection with at least one microorganism. The invention also concerns a bandaging material or patch comprising an antimicrobial composition which comprises metallic silver and metallic ruthenium as well as at least one vitamin or at least one vitamin derivative. The antimicrobial composition (“AgXX”) has a broad-spectrum effect against bacteria (a: E. coli) and fungi (b: Pathogen yeast and c: Penicillium).

a) Escherichia coli (additionally silver (“Ag”) as control),
b) Candida parapsilosis,
c) Penicillium notatum.

A biodegradable and biocompatible barrier membrane of piezoelectric nano composites of Metallic Oxide (MO) (e.g., Magnesium oxide, Zinc oxide and iron oxide)-PLLA (Poly-L-lactide), which can be subjected to acoustic pressure from ultrasound, to generate useful electrical charge for enhanced bone regeneration and enhanced antibacterial effects for guided bone regeneration to treat dental diseases, such as periodontitis.

The invention relates to compositions including magnesium-lithium alloys containing various alloying elements suitable for medical implant devices. The devices may be constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also relates to methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, such as but not limited to, orthopedic, dental, craniofacial and cardiovascular surgery.

The present invention relates to an antimicrobial material comprising a substrate and a metal component, wherein the metal component comprises chemically bonded copper and zinc. The invention also relates to methods of manufacturing the antimicrobial material described herein.

Provided is a method that achieves tunable crosslinking and reversible phase transition of hydrogels. The method is useful for preparing 3D-printable hydrogel, for example, for wound healing, aneurysm treatment or tissue regeneration.

The present disclosure relates to mesoporous glasses as well as uses of such glasses, for example, as hemostats.

Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.