A61L2300/11

DRUG DELIVERY COMPOSITIONS AND METHODS
20170000824 · 2017-01-05 ·

A drug delivery composition is disclosed which includes a triple salt proxy functional group and at least one amino acid functional group. A method of forming the drug delivery composition includes reacting a triple salt with at least one amino acid in an aqueous environment. A biodegradable fabric is disclosed which includes a polymerized structure of a triple salt proxy functional group and at least one amino acid functional group.

Oxygen-generating cryogels

Disclosed are nanocomposite oxygen-generating cryogels and their uses in reducing hypoxia in a biological tissue, such as a tumor. Methods of treating cancer with the disclosed cryogels are also provided.

IN-SITU INJECTABLE HYDROGEL ROD USING CROSSLINKED HYDROGEL, METHOD FOR MANUFACTURING SAME, AND BIOMEDICAL USE THEREOF

The present invention relates to an injectable hydrogel rod using a crosslinked hydrogel, a method for manufacturing same, and biomedical use thereof. According to the present invention, by adjusting the contents of a polymer, an enzyme and hydrogen peroxide to a certain ratio to manufacture an injectable hydrogel rod, the initial release amount of a drug injected into the hydrogel rod is controlled, and thus, compared to existing hydrogel-based injectable implants, the hydrogel rod exhibits sustained release above an effective concentration for a long period of time and greatly reduces elimination into surrounding tissues, which may result in an increased therapeutic effect and remarkably reduced side effects.