The present disclosure provides a coating applicator operable to apply a coating of a therapeutic agent upon an object comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, an atomizer operable to atomize the therapeutic agent, and a source of vacuum in communication with the device compartment. The coating applicator may further comprise a drier, and the drier may comprise an arrangement to operate the source of vacuum for a time sufficient to promote drying of applied therapeutic agent. Deposition of the atomized therapeutic agent may be promoted by contacting the atomized therapeutic agent while the object is in a chilled condition and by contacting the object with atomized therapeutic agent while the atomized therapeutic agent is in a heated condition. Related methods are also disclosed.

Novel, lubricious antimicrobial coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes at low temperatures that do not deform the device and preserves the antimicrobial effectiveness of the antimicrobial agent. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.

A method of producing metallic medical supplies includes supplying a metallic material selected from the group consisting of Ti, a Ti alloy, stainless steel and a CoCr alloy as a base material; treating the base material by carrying out anodic oxidation treatment in which an acid electrolytic bath or an alkali electrolytic bath is used as an electrolytic solution, and pulsed current having a frequency of 50 to 10,000 Hz is applied to the base material in the electrolytic solution to carry out electrolysis treatment to form a film having micro pores and/or micro unevennesses having a density of 510.sup.4/mm.sup.2 or more on a surface of the base material; and carrying out iodine-impregnation treatment to impregnate the film with iodine or iodine compounds, wherein the metallic medical supplies have an antimicrobial activity value of not less than 2 to not more than 4.

The present invention is directed to coated medical devices, such as implantable and coatable devices, such as sutures, with expanded antibacterial properties, handling, knot slide and in-situ performance and processes for their manufacture and use.

A wound healing composition and method for treating acute and chronic wounds and skin conditions includes a wound healing composition or formulation including a mixture of buckwheat honey, methylglyoxal and povidone-iodine.

An entirely or partially implantable medical product with a negatively charged surface for repulsing bacteria has a superficially bonded substance with a permanently negative excess charge, which substance is inert against cells of the human body and the bacteria contained therein.

An embolic material contains at least one type of polymer and a liposoluble contrast medium. A method for producing an embolic material includes extruding a raw material that is in a molten state into a solvent, and cooling the raw material so as to solidify the raw material. The raw material contains a polymer and a liposoluble contrast medium.

A method of reducing surgical site infection (SSI), using a coated medical device having a tissue penetrating surface and an abradable coating on the medical device comprising at least one antimicrobial agent in the coating.

A bioflexible elastomer intestinal anastomosis stent based on a PTMC-b-PEG-b-PTMC copolymer, and a preparation method. Biocompatible degradable polymer medical materials, i.e., PTMC and PEG, are selected, an electrostatic spinning method is used for preparation, the size of an anastomosis tube can be adjusted according to the size of a human lumen, and the anastomosis tube is designed to not only be suitable for an anastomat of the small intestines and large intestines, but also suitable for an anastomotic and pre-supported lumen anastomat of an esophagus, artery, vein, etc. The anastomosis tube prepared has a thin wall and excellent elasticity, and in order to facilitate suturing by a doctor during a clinical surgical operation, the anastomosis tube is innovatively and seamlessly sleeved outside a plant cellulose tube having high hardness.

The invention relates to a catheter hub made of a non-elastomeric plastic that contains homogeneously distributed, molecularly dispersed polychlorinated phenoxyphenol (PCPP), in particular 5-chloro-2-(2,4-dichloro-phenoxy)-phenol) (Irgasan).