Described are polymers and methods of forming and using same.

The present invention includes multifunctional compositions, methods and binding systems to provide disinfecting and deodorizing coatings for hard and soft surfaces, inorganic and organic solid surfaces and particulate media and other related substrates, including human and animal skin and skin lesions; to provide neutralizing functions for malodors generated by both human, animal and industrial fluids and solid wastes; and to provide neutralizing and degrading functions for nuisance and noxious chemicals. The present invention provides compositions and methods for producing disinfecting, oxidizing and enzyme-inhibiting fluids enabling preparation of durable, stable biocidal and deodorizing coatings and media which can be widely used for biological agent control, prevention and elimination of odors, and degradation of noxious agents susceptible to chemical oxidation, and which take forms that are inoffensive to users and offer high convenience.

An implantable medical instrument is made of an iron-based alloy, comprising an iron-based alloy substrate and a drug-loaded coating. The drug-loaded coating comprises a polymer and an active drug; the weight average molecular weight of the polymer is greater than or equal to 50,000 and less than or equal to 1,000,000; micro-pores having a diameter of less than or equal to 10 micrometers are formed in the drug-loaded coating; the percentage of the active drug released on the implantable medical instrument made of an iron-based alloy is greater than or equal to 4t.sup.1/21 and less than or equal to 6.9t.sup.1/2+63, wherein t (0, 28], and t represents sampling time/days.

Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.

A method and apparatus are disclosed for forming a drug coating layer capable of preventing breakage of elongated drug crystals on a surface of a balloon and maintaining the drug crystals in an appropriate shape in order to act on a living body. The method includes supplying a coating solution which contains the water-insoluble drug, a water-soluble additive, an organic solvent, and water to the surface of the balloon and evaporating the organic solvent and the water to form an additive layer containing the water-soluble additive and a protruding crystal having a tip end protruding from the additive layer, cutting a surplus portion protruding from the additive layer of the protruding crystal from a part surrounded by the additive layer and forming the part surrounded by the additive layer as the elongated body, and removing the cut-out surplus portion from the drug coating layer.

The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

The invention relates to an implant for subcutaneous implantation having a substantially cylindrical, conical or spiral-shaped base body which has a lateral surface. The base body consists of a completely resorbable biodegradable polymer. The implant is further configured for blunt implantation. In addition, the biodegradable polymer is enriched with a medicinally relevant active ingredient.

A bone graft composition comprising a calcium phosphate putty is provided. A method of repairing a bone defect in a patient by applying the bone graft composition is also provided.

Dermal filler compositions presented herein can contain a vitamin that is conjugated to a hyaluronic acid.

Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.