An absorbent article comprising a substantially water-free skin care composition comprising from about 40% to about 90% by weight of at least one emollient derived from a renewable resource and from about 10% to about 60% by weight of at least one immobilizing agent derived from a renewable resource; wherein the skin care composition has a DSC Percent Melt at 50 C. from about 10% to about 50%.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

A wetness indicator composition comprising at least one pH-indicator colorant, from about 0.001% to about 75% by weight of at least one color-stabilizer, and from 0.1% to 70% by weight of at least one hardening agent, and wherein the wetness indicator has a defined and properly selected hot to cold solidification rate, hardness and melt point.

The present disclosure provides click-crosslinked hydrogels and methods of use.

Disclosed are compositions, materials, garments, devices, and methods for controlling or neutralizing offensive odors associated with mammalian urine. For example, disclosed are personal care products (e.g., diapers), deodorizing colloidal compositions, urine-based fertilizers, portable urination systems, and methods of their use. Such deodorizing colloidal compositions, urine-based fertilizers, portable urination systems are characterized in that they contain an acrylate polymer comprising at least one acrylic acid monomer or salt thereof, which imparts a odor-neutralizing effect. Also provided are methods of recovering water from the systems disclosed herein.

A barrier layer and corresponding method of making provide anti-inflammatory, non-inflammatory, and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device structure to provide anti-adhesion characteristics, in addition to improved healing, non-inflammatory, and anti-inflammatory response. The barrier layer is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent.

A hot melt wetness indicator comprising an adhesive base composition utilizing a halogen-free species, namely nitrazine yellow, to trigger color change in hygiene articles, such as disposable diapers, to serve as moisture or wetness indicator upon insult. In some embodiments of the invention, the wetness indicator turns from yellow to purple.

Fatty acid-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.

Compositions including a complex of fatty acids (e.g., including one or more C4 to C40 fatty acids, such as a C4 to C20 fatty acid) and one or more amino acids (and particularly one or more amino acids having electrically charged basic side chains, e.g., Arginine, Lysine, etc.) for use as an anti-pathogenic composition. In particular, described herein are compositions of decanoic acid:Arginine in which the decanoic acid and Arginine for a complex having a lamellar supramolecular structure.

Provided is a lyophilized implant configured to fit at or near a bone defect to promote bone growth, the lyophilized implant containing a biodegradable polymer in an amount of about 0.1 wt. % to about 20 wt. % of the implant, mineral particles in an amount from about 0.1 wt. % to about 75 wt. % of the implant, and an oxysterol in an amount of about 5 wt. % to about 90 wt. % of the implant. Methods of making and using the implant are further provided.