The present invention provides a bone cement composition. The bone cement composition includes a developing particle, an acrylic polymer, and an acrylic monomer, wherein a specific surface area of the developing particle is in a range from about 0.1 m.sup.2/g to about 5 m.sup.2/g. The present invention further provides a bone cement composition kit. The bone cement composition kit includes a power component and a liquid component, respectively stored in separate containers, wherein the power component includes a developing particle and an acrylic polymer, and the liquid component includes an acrylic monomer. A specific surface area of the developing particle is in a range from about 0.1 m.sup.2/g to about 5 m.sup.2/g.

Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.

An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.

Methods, devices and systems are provided for determining a connection state of an all wheel drive (AWD) assembly in a vehicle. The method includes receiving, by a vehicle, a message indicative of a hazard and a hazard location on the road and determining a distance to the hazard location from the vehicle. In response to the distance to the hazard location being below a first threshold distance, a state for an AWD assembly in the vehicle is set to a connect state. In response to the distance to the hazard location being above the first threshold, the time for the vehicle to reach the hazard location is determined. If the time to the hazard location is below a threshold AWD connection time, the state for the AWD assembly is set to the connect state.

The present invention relates to: an amorphous of spherical embolisation hydrogel having a degradation time that can be precisely controlled in blood vessels; and a preparation method therefor.

Systems and methods for fixing a stent in position in an anatomical lumen. Such systems and methods include an intra-luminal stent and a magnet, implanted, for example, in the subcutaneous layer of the subject. The stent and the magnet are magnetically coupled such that the magnetic forces fix the stent in position. Use of the invention permits fixation of an intra-luminal stent to avoid stent migration while minimizing tissue damage.

A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.

The present disclosure relates to injectable compositions capable of forming a scaffold in situ at an intervertebral disc site, the composition comprising: (a) a biocompatible polymer; and (b) a biocompatible solvent system in sufficient amount to solubilize the biocompatible polymer in sufficient degree to allow injectable delivery to a disc site.

Described are fibrous materials comprising a plurality of fibers having a longitudinal alignment gradient and/or a longitudinal composition gradient. Also described are methods of preparing the fibrous materials thereof and methods of treating organ or tissue damage with the fibrous materials.

Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.