A blood bag system is provided with a liquid drug bag having an internal storage space in which a liquid drug is stored, and a third tube that is connected to the liquid drug bag and has a flow path therein connected to the storage space. A retention mechanism for separably retaining the liquid drug bag and the third tube is provided between the outer surface of the liquid drug bag and the outer peripheral surface of the third tube. The third tube can thus be inserted together with the liquid drug bag when the liquid drug bag is accommodated in a liquid drug bag pocket of a centrifugal transport device.

A tube winding bobbin is accommodated in a segment pocket of a centrifugation transfer device in which a blood bag system is set. The blood bag system is provided with a plurality of sealed tubes which extend for a predetermined length and which have an occluded lumen therein. The tube winding bobbin has a winding part around which the plurality of sealed tubes are wound, a pair of side parts connected to both ends of the winding part, and an engagement part engageable with a wall part constituting the segment pocket.

A blood bag system includes a PPP bag and a liquid drug bag which are accommodated adjacent to each other in pockets of a centrifugal drum of a centrifugal transport device. In addition, the blood bag system includes a retaining portion that retains the PPP bag and the liquid drug bag together, and includes a cassette accommodated in the pockets in a retaining state of the retaining portion. The cassette has a detachment mechanism capable of detaching at least the PPP bag.

A blood bag system is provided with a PPP bag that is accommodated in a PPP bag pocket, and a liquid drug bag that is accommodated in a liquid drug bag pocket provided adjacent to the PPP bag pocket. The PPP bag includes a first internal space and a seal part that seals the periphery of the first internal space. The liquid drug bag includes a second internal space and a seal part that seals the periphery of the second internal space. A connection part that separably connects the seal part and the seal part is provided there between.

A blood bag system includes a blood bag having a storage space for storing blood, a first tube that is connected to the blood bag and has a first flow path for communicating with the storage space, and a sealing member that is provided in the first tube and opens the first flow path by a breaking action. The first tube includes, at a position near the sealing member, an engagement portion for engaging with a centrifugal transport device with the sealing member disposed at the position where the breaking action is performed.

A clamp of a blood bag system has a first clamp mechanism for closing a second flow path of a second tube, and a second clamp mechanism for closing a third flow path of a third tube. The first clamp mechanism is configured not to open the second flow path of the second tube once closed, and the second clamp mechanism is configured to open the third flow path of the closed third tube.

A container for blood or a blood component is provided, the container comprising one or more container walls defining an interior chamber, the container walls comprising one or more layers, the layers comprising or consisting of a composition comprising one or more polymeric materials and at least one extractable agent selected from the group consisting of a terephthalate ester, a cyclohexane dicarboxylic acid ester, a citrate ester, and a polyol ester, wherein the container further comprises one or more additional components, wherein the container comprises less than about 3% (w/w) of di-2-ethylhexyl phthalate (DEHP), preferably wherein the container comprises less than about 3% (w/w) of phthalates. Thereby, improved blood products are provided in which the DEHP or overall phthalate content is reduced.

Provided are a blood bag system and a blood treatment method capable of securely and efficiently obtaining a medium specific gravity blood component having a sufficiently low content rate of a light specific gravity blood component. In a blood bag system (10) used for a blood treatment method, in a transfer completed state in which whole blood in a first bag (12) is centrifuged to transfer blood plasma to a second bag (14) through a first transfer tube (24) and transfer red cell concentrates to a third bag (16) through a second transfer tube (26), a buffy coat is left in the first bag (12). In the transfer completed state, when a platelet added solution is transferred from a fourth bag (18) to the first bag (12) on which a centrifugal force acts through a third transfer tube (28), blood plasma in the buffy coat is discharged from the first bag (12).

Disclosed is a bioprocessing system comprising apparatus (200) including a centrifugal separation housing (210) having a temperature controllable compartment (215) for removably accepting a separation chamber (50), the apparatus further comprising at least one mixing station (250) for supporting one or more fluid storage vessels (10, 20, 30, 40), the station including a temperature controllable area (252) for increasing or decreasing the temperature of the contents of the or each supported vessel. The system further includes a disposable fluidic arrangement (100) including a centrifugal separation chamber (50) removably mountable within the compartment (215) and having one or more ports (52) allowing fluid ingress into, or egress out of the chamber, via the one or more ports in use, said ports being in fluid communication with one or more of said fluid storage vessels via fluid conduits (12, 22, 32, 42) and via one or more valve arrangement.

A method is provided for controlling fluid flow through a tubing segment is provided in which a pump draws fluid through the tubing segment using negative pressure P. The method includes the steps of: a) operating the pump at an initial commanded fluid flow rate to draw fluid through the tubing segment; b) measuring on a continuous basis the P in the tubing segment; c) determining into which of four zones the measured P falls, a first zone being where P>X.sub.1, a second zone being where X.sub.1>P>X.sub.2, a third zone where X.sub.2>P>X.sub.3, and a fourth zone where X.sub.3>P; d) if P is in the first zone for greater than a first pre-established time period, then increasing the commanded flow rate of the pump and returning to step b); e) if P is in the second zone, then continuing to operate the pump at the flow rate at which the pump is currently operated and returning to step b); f) if P is in the third zone, for greater than a second pre-established time period, then decreasing the commanded flow rate of the pump and returning to step b); and g) if P is in the fourth zone, then commanding the pump to stop. A system including a programmable controller configured to automatically perform the method is also disclosed