An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a tube set including a connector (21) for connection to a patient line (3) for access to the peritoneal cavity of the patient. A flow pump (41-43) is arranged for addition and removal outflow and inflow (recirculation) of fluid from/to the peritoneal cavity. An osmotic agent peristaltic pump (16) is arranged for replenishment of glucose solution to the fluid added to the peritoneal cavity for promoting ultrafiltration. The glucose is replenished intermittently for keeping a concentration of glucose substantially constant in the peritoneal cavity. The flow pump comprises a pressure chamber (43) with rigid walls and a flexible pump bag (41) arranged therein. An air pump (45) pressurizes the chamber for outflow of fluid from the peritoneal cavity by a sub pressure and inflow of fluid to the peritoneal cavity by an overpressure, which pressures are maintained within safe limits.

An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a tube set including a connector (21) for connection to a patient line (3) for access to the peritoneal cavity of the patient. A flow pump (41-43) is arranged for addition and removal outflow and inflow (recirculation) of fluid from/to the peritoneal cavity. An osmotic agent peristaltic pump (16) is arranged for replenishment of glucose solution to the fluid added to the peritoneal cavity for promoting ultrafiltration. The glucose is replenished intermittently for keeping a concentration of glucose substantially constant in the peritoneal cavity. The flow pump comprises a pressure chamber (43) with rigid walls and a flexible pump bag (41) arranged therein. An air pump (45) pressurizes the chamber for outflow of fluid from the peritoneal cavity by a sub pressure and inflow of fluid to the peritoneal cavity by an overpressure, which pressures are maintained within safe limits.

An assembly includes first and second assemblies, the first assembly including a frame defining a recess, a first plate disposed within the recess, and a bellows disposed between the first plate and an inner surface of the frame. The second assembly includes a second plate configured to be opposite the first plate when the first assembly is in a closed position relative to the second assembly. The first assembly is configured to move relative to the second assembly between an open position and the closed position, and a latch assembly configured to hold the first assembly to the second assembly in the closed position. The bellows is configured to inflate to apply a force to the first plate towards the second plate when the first assembly is in the closed position.

An assembly includes first and second assemblies, the first assembly including a frame defining a recess, a first plate disposed within the recess, and a bellows disposed between the first plate and an inner surface of the frame. The second assembly includes a second plate configured to be opposite the first plate when the first assembly is in a closed position relative to the second assembly. The first assembly is configured to move relative to the second assembly between an open position and the closed position, and a latch assembly configured to hold the first assembly to the second assembly in the closed position. The bellows is configured to inflate to apply a force to the first plate towards the second plate when the first assembly is in the closed position.

An example article includes a rigid member defining a plurality of fluid flow paths and a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the respective lumen and unoccluded in the absence of the externally applied pressure. Each flexible tube is configured to be fluidically connected to a flow path of the plurality of flow paths, and different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes.

An example article includes a rigid member defining a plurality of fluid flow paths and a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the respective lumen and unoccluded in the absence of the externally applied pressure. Each flexible tube is configured to be fluidically connected to a flow path of the plurality of flow paths, and different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes.

Systems and method for monitoring the glucose concentration of a patient during a peritoneal dialysis session, and automated administration of a medication in response to the glucose concentration falling outside a specified range. The system includes a peritoneal dialysis system, a glucose sensor and at least one medication infusion pump. The peritoneal dialysis system includes a control system, and a peritoneal dialysate generation flow path fluidly connectable to a patient. The glucose sensor is in communication with the control system and positioned to continuously measure the glucose concentration of the patient during the peritoneal dialysis session. The control system can be programmed to provide automated administration of medication by the at least one medication infusion pump in response to changes in the glucose concentration of the patent during the hemodialysis session.

Systems and method for monitoring the glucose concentration of a patient during a peritoneal dialysis session, and automated administration of a medication in response to the glucose concentration falling outside a specified range. The system includes a peritoneal dialysis system, a glucose sensor and at least one medication infusion pump. The peritoneal dialysis system includes a control system, and a peritoneal dialysate generation flow path fluidly connectable to a patient. The glucose sensor is in communication with the control system and positioned to continuously measure the glucose concentration of the patient during the peritoneal dialysis session. The control system can be programmed to provide automated administration of medication by the at least one medication infusion pump in response to changes in the glucose concentration of the patent during the hemodialysis session.

A cartridge to be used for adsorption dialysis. A container having flexible walls are arranged to provide an inner space enclosing adsorption powder, comprising activated carbon, a phosphate adsorbent and a potassium ion adsorbent and other adsorbents. A sufficient amount of activated carbon is provided for adsorption of urea by the activated carbon. The cartridge forms a vacuum-packed transportation cartridge by generating a sub-pressure in the inner space, whereby the powder particles are immobilized and the cartridge becomes stiff. Before use, the cartridge is primed by introducing a liquid into the inner space, which introduction takes place at a low pressure. During use, dialysis solution is circulated through the cartridge, which is still exposed to a sub-pressure, whereby the flexible walls are sucked against the powder material. A peritoneal dialysis circuit comprises a filter, in which a primary circuit is formed with the filter and the peritoneal cavity and a secondary circuit is formed with the filter and the adsorbent cartridge.

A security token is provided having a communication interface with a communication transceiver; a circuit having encoded thereon an immutable hardware key; and a tangible, nonvolatile memory, the nonvolatile memory having stored thereon a mutable software key, the mutable software key including a cryptographic key and an expiry for the cryptographic key.