The disclosure relates to a subcutaneously implanted port device for establishing access to the vascular system of a patient requiring multiple blood treatments over an extended period of time. The systems, devices and methods disclosed herein may reduce miscannulation, promote intra-session hemostasis, and decrease the incidence of bacteremia and sepsis among other improvements and advantages. The devices include a port with a tapered seat for receiving an access tube, the first tapered seat having a proximal portion, a distal portion, and a conical section extending between the proximal portion and the distal portion; and an interface surface configured to engage a blood vessel or a vascular access catheter. The proximal portion of the tapered seat is configured to receive the access tube therethrough, and the tapered seat creates a mismatch fit with a diameter of the access tube when in use for an increase in flow during treatment.

A medical system, device, and methods are provided having programming to communicate with a mobile device; the medical device further having programming to authenticate the mobile device; the medical device granting access to one or more functions if the mobile device is authenticated.

Enhanced systems and methods for performing Direct Sodium Removal (DSR) therapy are provided in which an implantable device includes a variable speed motor-driven pump that may be programmed to output different flow rates at different stages of a DSR therapy session, wherein the system monitors operational parameters of the pump and is configured to generate an alarm condition indicative of a fault that may be displayed on a patient's smartphone to permit corrective action, and in which a catheter set implanted with the implantable device enables a DSR solution may be instilled into the patient's peritoneal cavity using a peritoneal catheter that is subsequently used to remove the DSR solution and sodium-rich ultrafiltrate from the peritoneal cavity to the patient's bladder.

The disclosure provides a method for preventing infection and microbial ingress in medical device connections between tubing sets and medical devices. The tubing set includes a male connector with a distal tip and a recess at the distal tip configured to trap bacterial, and deliver and confine antimicrobial into solution within a cavity formed by the recess. The surface of the recess includes an antimicrobial composition. In certain implementations a male luer comprises a tapered sealing member further comprising a recess containing chlorhexidine acetate.

A manifold for the circulation of fluids along predetermined circulation paths or circuits, for example, for extracorporeal dialysis machines. The manifold comprises a main body with a plurality of inner channels mutually connected to define the predetermined circulation paths, the predetermined circulation paths communicating with the exterior of the main body by way of at least one inlet and at least one outlet adapted to be connected to component parts and/or tubing of an extracorporeal dialysis machine, and dialysis machine equipped with the aforesaid manifold.

An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.

A medical treatment system is configured to output a predefined test pattern and to receive the signal by way of a microphone in order to test the volume and quality of the audio output in order to ensure the output audio signals effective to wake a sleeping patient. The failure of a processor to confirm the volume and fidelity of the audio output as well as the timeliness of the test pattern causes the processor to deny the resumption of a treatment and to generate an error signal.

A medical treatment system is configured to output a predefined test pattern and to receive the signal by way of a microphone in order to test the volume and quality of the audio output in order to ensure the output audio signals effective to wake a sleeping patient. The failure of a processor to confirm the volume and fidelity of the audio output as well as the timeliness of the test pattern causes the processor to deny the resumption of a treatment and to generate an error signal.

A peritoneal dialysis cassette that uses an external pump to drive fluid through the peritoneal dialysis cassette is provided. The peritoneal dialysis cassette can include two inlet/outlet ports connected to an inlet and outlet of the external pump. The external pump drives fluid through fluid passages in the peritoneal dialysis cassette connecting a plurality of other inlet/outlet ports, with one or more valves usable to selectively direct fluid through the peritoneal dialysis cassette.

A peritoneal dialysis cassette that uses an external pump to drive fluid through the peritoneal dialysis cassette is provided. The peritoneal dialysis cassette can include two inlet/outlet ports connected to an inlet and outlet of the external pump. The external pump drives fluid through fluid passages in the peritoneal dialysis cassette connecting a plurality of other inlet/outlet ports, with one or more valves usable to selectively direct fluid through the peritoneal dialysis cassette.