A blood purification apparatus in which whether or not the connection of a communicating line is appropriate can be determined more accurately. A blood purification apparatus includes a control device that is capable of executing a pressure-applying step in which a negative pressure or a positive pressure is applied to a flow route of one of a tube section and a blood circuit; a propagating step in which the negative pressure or the positive pressure applied in the pressure-applying step is propagated to the flow route of an other of the tube section and the blood circuit through the communicating line; and a checking step in which whether or not the propagation of the negative pressure or the positive pressure in the propagating step is successful is checked with reference to the pressure detected by the pressure-detecting device, and in which whether or not the connection of the communicating line is appropriate is checked with reference to whether or not the propagation of the negative pressure or the positive pressure is successful.

A controller for controlling an apparatus comprising a blood pump, oxygenator, and blood filtering system connected together by blood flow tubing and to a patient to circulate blood from the patient through the apparatus and back to the patient, to oxygenate and filter the blood, the controller comprising at least one communication interface operable to receive signals generated responsive to monitored parameters characterizing blood flow and/or quality of blood from the patient circulating through the apparatus and configured to: determine values for the monitored parameters based on the monitoring signals; determine whether or not a value determined for a given monitored parameter for blood circulating through the apparatus is within a normative range for the parameter; and generate an alarm to alert an operator of the system if the value is not within the normative range.

A device for establishing venous inflow to a blood reservoir of an extracorporeal blood circulation system includes a restricting unit for restricting a venous inflow line and a vacuum unit for supplying vacuum to the blood reservoir. The device includes a control unit that, upon setting the desired venous flow rate, automatically supplies a first actuating signal to the restricting unit for restricting venous inflow to the blood reservoir and supplies a second actuating signal to the vacuum unit for establishing a degree of vacuum within the blood reservoir, so as to achieve the set venous flow rate. The device includes a venous flow sensor.

A blood purification device includes a blood circuit for extracorporeally circulating blood of a patient; a liquid supply circuit for supplying a supply liquid to the blood circuit or to a blood purifier provided on the blood circuit and a waste liquid circuit for discharging the waste liquid from the blood purifier. Each of the blood circuit, the liquid supply circuit and the waste liquid circuit comprises a flexible tube. The blood purification device comprises a tube identification unit that performs a tube identification process for identifying a tube used for the blood circuit, the liquid supply circuit or the waste liquid circuit or determining whether or not there is an abnormality in the tube, based on an amount of liquid sent from a peristaltic pump provided on the blood circuit, the liquid supply circuit or the waste liquid circuit, or pressure fluctuation in the circuit, caused when driving the pump for a predetermined time.

A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the volume/weight of anticoagulated plasma that is collected is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume/weight of raw plasma within a plasma product having the maximum volume permitted by the FDA nomogram. In a plasmapheresis procedure having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the donor's increasing hematocrit, thus resulting in a greater total volume of plasma product to be collected during the plasmapheresis procedure.

The present invention provides a method, system, and apparatus that can substantially reduce the recirculation of venovenous extracorporeal membrane oxygenation (VV ECMO) associated with the two-site, single-lumen cannulation approach. Actively-controlled flow regulators comprising balloon, occluder and reservoir can be individually or collectively equipped on the drainage and/or infusion cannulas to accomplish the goal of maximizing VV ECMO support efficacy. Three specific embodiments are introduced to illustrate the practical enforcement of the proposed blood flow control in reference to the heart rhythm, aiming at achieving the maximal reduction of oxygenated blood flow recirculating back to the VV ECMO circuit.

A dialysis catheter with an elongate body has a distal end defining blood removal and return ports communicating with internal blood removal and return lumens extending through the elongate body. A sensing pathway is disposed in or on the elongate body. A vascular dimension sensor is provided to dynamically measure changes in dimension of the SVC or IVC during dialysis. The sensor communicates with a control system and may be controlled or positioned via the communication pathway of the catheter body. Systems disclosed included integrated closed-loop treatment based on monitored vascular dimension input. Methods included patient optimized treatments incorporating treatment modulation based on dynamic vascular dimension monitoring.

The present invention relates to a system (5) for temperature management for patients in stationary and mobile ECLS and/or ECMO therapy, with at least one disposable (7) and a fluid circuit (9), wherein the disposable (7) comprises at least one reservoir (10) or bag provided with at least one supply line (12) and a drain line (14), further provided at least one pumping unit element (11) as part of the disposable (7), by means of which liquid in the reservoir (10) or bag can be pumped through the fluid circuit (9).

Furthermore, the present invention relates to a disposable (7) for such a system (5).

A blood flow management device includes: a blood flow sensor that is capable of acquiring blood flow data being data related to blood flow by being arranged in direct or indirect contact with a measurement portion of a target site of a subject; and a blood flow adjustment means that adjusts the blood flow in the target site in accordance with the blood flow data.

A display apparatus for a user interface of a medical instrument avoids erroneous input of numerical values when a user inputs information. A display apparatus includes a numerical value information input section, a selectable target information display section, and a target selection section. A plurality of the setting information selection sections are displayed to be associated with corresponding selectable target information, and a plurality of pieces of selectable target information are arranged so as to be adjacent to each other based on a same standard. The numerical value information input section corresponding to the selected target selection section is displayed simultaneously on a same screen. A range of the selectable target information is changed visually and displayed in response to the numerical value information which is input to the numerical value information input section.