An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32); a control unit (12) is configured for calculating a sodium concentration value for the blood; the estimation of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the isoconductive sodium concentrate and of an offset contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate and phosphate.

An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32), a preparation device (9) for preparing and regulating the composition of the dialysis fluid; a control unit (12) is configured for setting a sodium concentration value for the dialysis fluid in the dialysis supply line (8) at a set point; the setting of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the blood plasma conductivity and of an adjustment contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate, and phosphate.

Non-invasive heartbeat sensor for determining a heart rate in a conduit of an extracorporeal blood treatment apparatus, comprising one source for directing an optical signal towards the blood flowing in the segment; one detector for receiving an optical informative signal comprising the signal emitted by said source after passing the blood, and emitting respective output signal; a controller receiving the respective output signal and retrieving a heartbeat frequency and a heart rate value, based on the output signal, wherein the informative signal is altered by flow perturbation of the blood partially generated by the flow impulses originated by the heart.

The invention discloses a blood cleaning device, comprising a first hyperbaric oxygen ring-shaped container, a second hyperbaric oxygen ring-shaped container, an adsorption particle ring-shaped container, and a control panel; the first hyperbaric oxygen ring-shaped container is connected with an original blood inlet pipe; the second hyperbaric oxygen hyperbaric container is provided with a cleaned blood outlet pipe; the cleaned blood outlet pipe is provided with an outlet valve; the first hyperbaric oxygen ring-shaped container and the adsorption particle ring-shaped container are connected by a first connecting pipe and a second connecting pipe; the adsorption particle ring-shaped container is connected to the second hyperbaric oxygen hyperbaric container by a third connecting pipe. The invention can clean the blood, reduce the substances harmful to the human body in the blood, achieve the purpose of improving the sub-health status of the human body, and has a good promotion prospect.

A system delivers gas-enriched blood or liquid within the vasculature of a patient while partially obstructing a flow of blood within the vasculature of the patient. The system may include a first catheter configured for inserting into a vasculature of a patient to deliver gas-enriched blood or liquid to a region of the vasculature of the patient. The system may include a second catheter configured for inserting into the vasculature of the patient. The second catheter includes lumens and an occlusion structure configured to partially obstruct a flow of blood within the vasculature of the patient while allowing the first catheter to deliver the gas-enriched blood or liquid to the region of the vasculature, and to divert the blood flow to the region where the gas-enriched blood or liquid is delivered.

A bioprocessing system for protein manufacturing from human blood is provided that is compact, integrated and suited for on-demand production and delivery of therapeutic proteins to patients. The patient's own blood can be used as the source of cell extracts for the production of the therapeutic proteins.

A device for establishing venous inflow to a blood reservoir of an extracorporeal blood circulation system includes a restricting unit for gradually closing a venous inflow line and a vacuum unit for supplying vacuum to the blood reservoir. The device includes a control unit that supplies a first actuating signal to the restricting unit for restricting venous inflow to the blood reservoir and supplies a second actuating signal to the vacuum unit for establishing a degree of vacuum within the blood reservoir.

An extracorporeal blood treatment apparatus (1) and a method for checking the connection of a soft bag (30, 24; 33, 34) in the apparatus (1). The apparatus (1) comprises a blood treatment device (2), an extracorporeal blood circuit (3, 5) and a fluid circuit (8, 12, 15, 17, 18, 22; 41, 42, 44). A control unit (32) is configured to check the connection of a soft bag (30, 24; 33, 34) to the extracorporeal blood circuit (3, 5) or to the fluid circuit (22; 41, 42, 44) through the following procedure: sucking a medium from a connecting zone (29) through a blood pump (6) or a fluid pump (23; 37, 39) of the apparatus (1); measuring at least a pressure trend (P1, P1-P2, P2-PI, Pwdr, Pwdr-Pret, Pret-Pwdr) over time in the extracorporeal blood circuit (3, 5) or in the fluid circuit (22; 41, 42, 44) through at least a pressure sensor (25, 26); establishing from said measured pressure trend (P1, P1-P2, P2-PI, Pwdr, Pwdr-Pret, Pret-Pwdr) if the soft bag (30, 24; 33, 34) is connected to the extracorporeal blood circuit (3, 5) or to the fluid circuit (22; 41, 42, 44) at the connecting zone (29).

A blood purification device includes a blood circuit for extracorporeally circulating blood of a patient; a liquid supply line for supplying a supply liquid to a blood purifier provided on the blood circuit or to the blood circuit a peristaltic liquid supply pump provided on the blood circuit or on the liquid supply line; a peristaltic waste liquid pump provided on a waste liquid line through which a waste liquid is discharged from the blood purifier; a water balance amount detection unit for detecting a water balance amount of the supply liquid and the waste liquid; and a water balance amount control unit that corrects one or both of pump speeds of the liquid supply pump and the waste liquid pump so that the water balance amount detected by the water balance amount detection unit matches a target water balance amount. The water balance amount control unit is configured to be able to switch between a first correction condition for correcting the pump speed on every water balance amount detection and a second correction condition for correcting the pump speed based on a plurality of water balance amount detection results.

A system includes a dialyzer having a blood side and a dialysate side, a first extracorporeal circuit including one or more first fluid connectors structurally configured to connect the blood side of the dialyzer to the vascular system of a kidney patient, and a second extracorporeal circuit including one or more second fluid connectors structurally configured to connect the dialysate side of the dialyzer to the vascular system of a healthy animal. The present teachings may thus include a system where hemodialysis is performed using a healthy animal (e.g., a person with normal kidney function) to help remove harmful solutes from, and provide helpful solutes to, a kidney patient. In this manner, the healthy animal is “virtually donating” its kidney function to the kidney patient.