This disclosure describes devices, systems, and methods related to therapy devices including pumps that are operable in multiple operating modes. An exemplary wound therapy device includes a pump configured to be worn by a user and a controller coupled to the pump and configured to transition the pump from operating in a first operating mode to operating in a second operating mode responsive to a pressure of the wound therapy device satisfying a first pressure threshold. The first operating mode is associated with a first drive voltage that is different from a second drive voltage associated with the second operating mode.

A bone marrow aspiration device and associated method includes an introducer needle assembly and an aspiration needle assembly. The introducer needle assembly includes an introducer cannula having proximal and distal ends, each end including an opening, and a screw assembly coupled to the introducer handle. The screw assembly includes a threaded tube and a lead screw receivable in the threaded tube. An outer cover is disposed around and in sealing engagement with the threaded tube and the lead screw. The aspiration needle assembly is receivable in the introducer cannula and includes an aspiration cannula forming a channel for aspirating bone marrow and including a flexible portion that extends from a distal end along a length of the aspiration cannula. A length of the aspiration cannula that extends beyond the distal end of the introducer cannula is adjustable by advancing the lead screw into or reversing the lead screw out of the threaded tube.

An aspiration system includes a plurality of catheters located at least partially within the lumen of an outer sheath. The outer sheath and the catheters are configured to slide relative to each other between a first state in which the distal ends of the catheters are located within the lumen of the outer sheath, and a second state in which the distal end and an end length section of each catheter is extended through the distal end of the outer sheath and outside of the lumen of the outer sheath. The end length section of each catheter is configured to spring or flare outward relative to the first state, when the outer sheath and the plurality of catheters are in the second state. The distal end of the outer sheath may be placed in an inferior vena cava or iliac vein in a transplant kidney patient, adjacent at least one renal vein, with the outer sheath and the plurality of catheters in the first state. Then, the system may be transitioned to the second state to cause the end length sections of the catheters to spring or flare outward adjacent the renal vein. The catheters are connected to a suction source for aspiration through the catheter end length sections.

Disclosed herein is an automated urinary output monitoring system including urine collection assembly that includes a first drainage tube coupled between a urinary catheter and an interim container, and a second drainage coupled between the interim container and a final container. A scale measures the weight of urine collected in the final container and a display depicts the volume of urine collected in the final container. A vacuum pump can be coupled with the final container to draw urine from the interim container into the final container, and an air vent can isolate the patient from the vacuum within the final container. The system can be configured to wirelessly transmit urine volume data to an external computing device. A gyroscope can be coupled with the scale to determine the orientation of the scale. Logic of the system can calculate urine volume and correlate with the time of day.

Provided is a method of cleaning a body cavity using a device by coupling a distal end portion of a first cannula to the housing such that a lumen is in fluid communication with the first portion of the inner volume, the first cannula coupled to a vacuum source, then coupling a distal end portion of a second cannula to the housing such that a lumen is in fluid communication with the second portion of the inner volume, the second cannula being coupled to a fluid source, inserting a portion of the housing into a body cavity, conveying a fluid from the fluid source to the body cavity via the lumen of the second cannula, and withdrawing the fluid from the body cavity into the vacuum source concurrently with the conveying the fluid, via the lumen of at least the first cannula.

In some embodiments, a catheter device may include a catheter including a proximal end and a distal end. The catheter device may further include a connector coupled to the proximal end of the catheter. The connector may include a base having a recess configured to receive the distal end of the catheter and may include a hinged portion configured to couple to the base to clamp the catheter within the recess.

A catheter that includes a mechanism for deflecting a distal portion of a catheter may include a deflection knob including a first thread, a rod including a second thread that is coupled to the first thread, and a puller wire that is connected to the rod. The rod may additionally include a pocket to which the puller wire may be connected via a joining feature that may be secured in the pocket and attached to a proximal end of the puller wire. The joining feature may include a first ferrule joined, e.g., crimped, to the proximal end of the puller wire and a second ferrule secured, e.g., bonded, in the pocket and joined, e.g., crimped, to the first ferrule.

A device has a power source having a high voltage terminal and a low voltage terminal, an oil-free gas compressor, a first molecular sieve, multiple ionized gas generators, an outer metal pipe, an inner metal pipe, a dielectric insulating ceramic sheet, and a gas outlet pipe. The first molecular sieve is connected between the oil-free gas compressor and the ionized gas generators, and is capable of filtering out molecules in the gas except for oxygen. The outer metal pipe and the inner metal pipe are electrically connected to the low voltage terminal and the high voltage terminal respectively. The dielectric insulating ceramic sheet is mounted between the outer metal pipe and the inner metal pipe, and forms an ionizing space, which communicates with the ionizing space, with the outer metal pipe.

A device for carrying out a lavage-like, repetitive supply and draining of a flushing, cleaning or other therapeutically active substance in the context of a return-flow enema, the device comprising: a catheter unit (SK) for receiving and draining feces, which can be permanently placed atraumatically and anorectally; a flushing and collecting bag unit (5, SB) with a combined flushing and collecting function; and a hose unit (4) connecting the catheter unit (SK) to the flushing and collecting bag unit (5, SB), comprising a single-lumen or multi-lumen, film-like, flatly collapsible, hose, and enabling a bidirectional flow communication between the catheter unit (SK) and the flushing and collecting bag unit (5; SB); characterized by at least one throughflow element with a flow-direction-dependent throttle function, providing a large lumen for draining of the patient's intestinal contents into the flushing and collecting bag unit (5; SB), so that shaped stool fractions can be drained, and which facilitates a supply of liquid from the flushing and collecting bag unit (5; SB) towards the patient, but wherein the supply of liquid towards the patient is throttled, so as to be reduced in flow amount or flow speed in relation to the draining of the patient's intestinal contents and thereby reduces the supply of liquid to the patient to a non-irritating amount that is compatible with the patient avoiding painful sensations and/or vegetative responses by an immediate dilation of the patient's colon and/or a triggering of a premature or only partially coordinated defecation reflex.

The present solution provides trans-round window membrane (RWM) drug delivery. As an overview, the system can include a micropump that is connected to a flexible cannula. The cannula can include a stiffened and sharpened tip to facilitate insertion through the RWM. The cannula can be inserted through the RWM to improve the distribution of the delivered drug throughout the inner ear. The present solution can function as a small implantable or wearable device that can be used for both chronic and acute trans-RWM drug delivery. With this configuration, the micropump can constantly or intermittently deliver, over a period of days to months, small volumes of drugs from an internal reservoir.