This disclosure describes devices, systems, and methods related to oxygenated hemoglobin, the generation thereof, and the use thereof. An exemplary oxygenated hemoglobin therapy system includes an oxygen source configured to provide oxygen and a hemoglobin source configured to provide topical hemoglobin. The therapy system may also include a mixer which has a first inlet, a second inlet, and an outlet. The mixer is configured to mix the oxygen and the topical hemoglobin to form a mixture and to provide the mixture to a dressing via the outlet. The therapy system may further include the dressing. The oxygenated hemoglobin therapy systems described herein are suitable for use in medical devices, such as bandages, drapes, dressings, and wound closures.

Embodiments of negative pressure wound therapy systems and methods are disclosed. In one embodiment, an apparatus includes a housing, negative pressure source, circuit board, and one or more controllers. The circuit board can be supported by the housing and include a conductive pathway extending around at least part of a perimeter of a first side of the circuit board. The conductive pathway can be electrically coupled to an electrical ground for the circuit board. The one or more controllers can be mounted on the circuit board and activate and deactivate the negative pressure source.

A negative pressure wound therapy system can include a negative pressure source configured to provide, via a fluid flow path, negative pressure to a wound covered by a wound dressing. The system can include a controller. The controller can be configured to periodically activate the negative pressure source to maintain negative pressure in the fluid flow path between a low negative pressure setpoint and a high negative pressure setpoint. The controller can be configured to determine a change in a volume of the wound based on a difference between a first time and a second time at which the high negative pressure setpoint has been established in the fluid flow path, the second time being subsequent to the first time. The controller can be configured to provide indication of the change in the volume of the wound.

A negative pressure device for applying to skin is configured to define a sealed enclosed three-dimensional space when at least a portion of the device is sealed against the skin. The device includes a body including at least one expandable segment that is configured to expand after the device has been sealed against the skin.

A wound therapy system includes a dressing sealable over a wound and defining a wound space between the dressing and the wound, tubing fluidly communicable with the wound space, and a canister fluidly communicable with the tubing. The canister, the tubing, and the dressing define a sealed space that includes the wound space. The wound therapy system also includes a therapy unit coupled to the canister. The therapy unit includes a sensor configured to measure a pressure in the sealed space, a valve positioned between the sealed space and a surrounding environment and controllable between an open position and a closed position, and a control circuit. The control circuit is configured to control the valve to alternate between the open position and the closed position to allow airflow through the valve, receive measurements from the sensor, and determine a volume of the wound space based on the measurements.

A new system for negative pressure wound therapy is described. The system includes a patient tube set connecting the wound dressing to the suction container. The patient tube set provides separate channels for applying suction to the wound site and sensing the therapeutic pressure at the wound site. A restrictor valve may also be included in order to introduce a small air leak into the system to prevent occlusions in the patient tube set.

A system comprises a negative-pressure source including a pump and an electric motor for maintaining negative-pressure at the wound and a pressure sensor for sensing a wound site pressure (WP). The system further comprises a system controller coupled to the first pressure sensor and the electric motor. The system controller maintains the wound site pressure (WP) within a hysteresis band by the application of power to the electric motor from a battery power source, based upon, at least in part a flow rate (FR) of fluid between the pump and the wound site as determined by the system controller. The hysteresis band including a maximum wound site pressure (WPMax) and a minimum wound site pressure (WPMin).

This disclosure describes devices, systems, and methods related to therapy devices including pumps that are operable in multiple operating modes. An exemplary wound therapy device includes a pump configured to be worn by a user and a controller coupled to the pump and configured to transition the pump from operating in a first operating mode to operating in a second operating mode responsive to a pressure of the wound therapy device satisfying a first pressure threshold. The first operating mode is associated with a first drive voltage that is different from a second drive voltage associated with the second operating mode.

One implementation of the present disclosure is a method for dynamically controlling an alarm of a negative pressure wound therapy (NPWT) device, according to some embodiments. In some embodiments, the method includes initiating NPWT, comparing an initial pump duty to a threshold value to determine a dressing application quality, monitoring a leakage rate of the NPWT, setting a leak threshold value based on the dressing application quality, determining leakage event occurrences in response to the leakage rate exceeding the leak threshold value at multiple times, adjusting the leak threshold value based on at least one of a number of the leakage events over the time period, a time duration between sequentially occurring leakage events of the leakage events, and the dressing application quality, and causing a user interface device to display a leak alert in response to the leakage rate exceeding the adjusted leak threshold value.

Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a negative pressure source, a sensor, and a controller. The negative pressure source can provide negative pressure via a fluid flow path to the wound dressing. The sensor can monitor pressure in the fluid flow path. The controller can determine whether the wound dressing is coupled to a wound from a change in magnitude of pressure in the fluid flow path over time being more indicative of a steady state condition than a chaotic condition while the negative pressure source maintains negative pressure in the fluid flow path within a pressure range. In addition, the controller can output a first indication denoting that the wound dressing is coupled to the wound and a second indication denoting that the wound dressing is not coupled to the wound.