A medicament delivery device having a reservoir for holding a medicament, a pressurizing system that dispenses the medicament from the reservoir when operating, a hollow cannula for insertion into a patient, and a fluid delivery path disposed between the pressurizing system and the hollow cannula and communicating the medicament therebetween. The medicament delivery device also has a pressure sensor external to the pressurizing system, sensing a back pressure in the fluid delivery path, and providing an indication when the back pressure drops below a predetermined threshold after the pressurizing system ceases operation.

A drug injection device according to the present disclosure includes: a drug injector configured to electrochemically drive an electroosmotic pump to suck a drug from a drug storage and discharge the sucked drug to an injection target; and a controller configured to output, to the drug injector, a control signal corresponding to an amount-based injection sequence that enables the electroosmotic pump to be driven in an immediate injection mode, wherein the amount-based injection sequence includes at least one pulse block that defines a voltage pulse or a current pulse to be applied to the electroosmotic pump, each pulse block defines a pair of pulse signals including a forward pulse and a reverse pulse that are applied to the electroosmotic pump to alternately generate negative pressure and positive pressure, and the electroosmotic pump alternately generates negative pressure and positive pressure for each pulse block to suck and discharge the drug.

An infusion system includes a primary delivery device, a secondary delivery device, an ancillary device, and a manifold. The manifold includes a primary connection port fluidly coupled with the primary delivery device. A delivery connection port in fluid communication with the primary connection port is fluidly coupled with the ancillary device. A secondary connection port fluidly coupled with the secondary delivery device is in fluid communication with the primary connection port. The primary connection port is operable to permit bidirectional flow so that fluid flows from the primary delivery device through the primary connection port and through the delivery connection port to the ancillary device, and from the secondary delivery device through the secondary connection port and through the primary connection port to be received by the primary delivery device.

The invention relates to a sterile, ready-to-use, stable aqueous solution of ketamine suitable for direct intravenous infusion to a patient in need thereof, wherein the composition is disposed within a sealed infusion container as a premixture. The invention further relates to aqueous solutions of ketamine that are free of antimicrobials such as benzethonium chloride and are shelf-stable. The pharmaceutical compositions can be used, for example, wherein the subject is in need of anesthesia for a diagnostic or a surgical procedure.

Embodiments of the present disclosure relate to devices and methods for filling a medicament cartridge of a pump, including a user-wearable, ambulatory infusion pump. A vial adapter can be provided that can releasably secure a medicament cartridge and a vial of medicament. A fill rod can be releasably attached to a plunger of the medicament cartridge. A user can hold the vial adapter, with the medicament cartridge and vial secured thereto, in one hand and operate the fill rod with the other hand to fill the medicament cartridge with medicament from the vial.

An apparatus, system and method for regulating fluid flow are disclosed. An apparatus for infusing fluid into a patient includes a housing, a tube-contact member, a rotating arm, and a tube-retention cover. The housing has an opening on a front side of the housing. The opening is sized to receive a drip chamber having an inlet tube and an outlet tube. The tube-contact member contacts one of the inlet tube and the output tube of the drip chamber when inserted into the opening. The rotating arm is coupled to the tube-contact member and is configured to rotate along an axis. The tube-retention cover is configured to close when the drip chamber is initially loaded into the opening.

Aspects of electronic illuminator systems and methods are disclosed herein, including subsystems and methods of use. In one aspect, a sensory system for an electronic illuminator to detect the presence and color of a fiber optic cable is disclosed. The system comprises a fiber optic cable having a proximal end with a fiber funnel cap and a terminal end with a protective cover. An electronic illuminator that further comprises a housing, a printed circuit board (PCB), a light emitting diode (LED), and a power source. The system further comprises an ambient light sensor, configured within the housing of the electronic illuminator, wherein the ambient light sensor converts light intensity to a digital signal. The system further comprises a fiber detection assembly, having a three dimensional magnetic flux density. Lastly, the system comprises a cap color detection assembly, wherein the cap color detection assembly detects the color of the fiber funnel cap on the proximal end of the fiber optic cable.

Aspects of systems and apparatuses for medical infusion illumination are disclosed. In one aspect a system for medical infusion line illumination is disclosed. The system comprising an electronic illuminator. The electronic illuminator comprising a printed circuit board (PCB), a light emitting diode (LED), a lens configured with the LED, a power source to supply power to the PCB and LED; and at least one sensory assembly. The LED and lens of the electronic illuminator are configured to a side scattering fiber optic cable. The side scattering fiber optic cable comprises a fiber funnel cap at a proximal end to receive light from the LED through the lens of the electronic illuminator. The side scattering fiber optic cable further comprises a protective end cap at a distal end, wherein the protective end cap is polished on an interior surface to reflect light from the LED of the electronic illuminator.

An integrated capacitive flowmeter for an infusion pump is disclosed. A conductive plate is attached to a hammer element that moves according to a cam motion in a pumping mechanism of the pump to periodically compress an flexible infusion line loaded in the pumping mechanism. A processor measures a first capacitance between the conductive plate coupled to the hammer element and a conductor opposite the flexible infusion line when the flexible infusion line is loaded between the conductive plate and the conductor in the pumping mechanism. A volume of the fluid within the flexible infusion line during the filling phase is then determined based on the measured capacitance, and a flow rate determined based on the determined volume and a cycle speed of the pump. The speed of the pump can then be adjusted based on a difference between the determined flow rate and a programmed flow rate.

Aspects of electronic illuminator systems and methods are disclosed herein, including subsystems, methods of use, and computer-readable media thereof. In one aspect, a system includes a fiber detection assembly. The system further includes a cap color detection assembly. The system further includes a printed circuit board connected to the fiber detection assembly and the cap color detection assembly. The system is configured to illuminate a cable engaged with the system with an effect corresponding to the cable upon authenticating the cable.