The present invention is directed to an adjustable pressure injection device system for delivering an agent into a tree, comprising at least two fill bottles for containing the agent; a cap attached to the open end of the bottles, the cap comprising at least two ports and an on/off valve; a main line connected to the cap through a port, wherein the agent flows out of the bottle and into the main line; a parallel distribution system (PDS) connected to the main line, wherein the PDS comprises multiple ports, each port either being closed or connected to an injection line, and further wherein the PDS is optionally expandable by combining a PDS with additional PDS units; at least 2 injection lines connected to the PDS through the PDS ports, and an injection needle attached to each injection line, wherein the agent flows through the injection needle into the tree.

The present invention is directed to an adjustable pressure injection device system for delivering an agent into a tree, comprising at least two fill bottles for containing the agent; a cap attached to the open end of the bottles, the cap comprising at least two ports and an on/off valve; a main line connected to the cap through a port, wherein the agent flows out of the bottle and into the main line; a parallel distribution system (PDS) connected to the main line, wherein the PDS comprises multiple ports, each port either being closed or connected to an injection line, and further wherein the PDS is optionally expandable by combining a PDS with additional PDS units; at least 2 injection lines connected to the PDS through the PDS ports, and an injection needle attached to each injection line, wherein the agent flows through the injection needle into the tree.

Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining one or more measurement values of a physiological condition in the body of a user during an initial monitoring period and determining a fasting reference value for a metric based on the one or more measurement values. After the initial monitoring period, the method continues by obtaining an updated measurement value during a fasting period, determining a current value for the metric based at least in part on the updated measurement value, and generating a notification in response to a deviation between the current value and the fasting reference value exceeding a threshold indicative of insertion site loss or other loss of effectiveness.

Blood glucose control systems are disclosed. A blood glucose control system can receive a glucose level signal from a glucose sensor operatively coupled to a subject. The system can decode encoded data of the glucose level signal to obtain the glucose level of the subject and the indication of the glucose trend. The system can automatically calculate the dose control signal using a control algorithm configured to calculate regular correction boluses of glucose control agent in response to at least the glucose level of the subject. The system can select a dose control signal encoding profile from a plurality of dose control signal encoding profiles and, based on the dose control signal encoding profile, encode the dose control signal such that the pump controller can read the dose control signal. The system can transmit an encoded dose control signal to the pump controller.

A fluid pathway connection includes a piercing member, a connection hub, and a sliding pierceable seal, wherein the sliding pierceable seal is configured to move from a first position, where the piercing member is initially retained within a sterile cavity between the connection hub and the sliding pierceable seal, to a second position, where the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. The fluid pathway connection may further be configured to move to a third position where one or more interconnects and/or one or more corresponding contacts are permitted to transmit a signal to the user. Such fluid pathway connections may be integrated into a drug container having a barrel and a plunger seal. A drug delivery pump includes such integrated fluid pathway connections and drug containers.

Methods for programming an implantable drug delivery device using a mobile computing device that include establishing a connection with a telemetry unit configured for wireless communication with the implantable drug delivery device, displaying user-selectable drug delivery settings for the implantable drug delivery device, receiving at least one selection of a drug delivery setting, translating the received selection into a signal format readable by the telemetry unit, and sending the translated signal to the telemetry unit to program the implantable drug delivery device. Further embodiments include telemetry units for communication with an implantable drug delivery device, and patient programmers and a method for patient modification to a programmed drug delivery regimen.

A sensor patch, system, and method for detecting a fluid leaked from a target site of a subject are provided. The sensor patch (100) includes a first detecting unit (127), a second detecting unit (128), and a patch body (110). The first detecting unit (127) includes a first pair of sensors (120A) respectively having a first end (121A) configured to be placed approximating the target site, while the second detecting unit (128) includes a second pair of sensors (120B) respectively having a first end (121B) configured to be placed away from the target site. Each sensor includes a conductive wire (125) and an insulating sheath (126) encapsulating the conductive wire (125) in a manner that a portion of the first end (121A, 121B) of the conductive wire (125) is exposed yet without directly contacting the subject's skin. The patch body (110) has an adhesive surface (104) for securing the first and second detecting units (127, 128) to the subject. The sensor patch enhances the detection specificity.

A valve assembly including a housing having a base and an outer shell, which forms a proximal cavity and a distal cavity joined by a canal; an inner housing configured for longitudinal movement within the distal cavity; a seal positioned within the distal cavity that together with the longitudinal movement of the inner housing regulates the flow of fluid through the valve assembly; and one or more selected from the group consisting of the base notched with one or more notches and the inner housing having one or more through slots aligned to permit access to the one or more notches, the seal being a reversibly deformable sealing pin, and a torque limiter mechanism configured to resist the longitudinal movement of the inner housing distally until a sufficient radial force is applied.

Containers for collecting fluid are provided that include a reservoir comprising a plurality of panels enclosing an interior, side panels of the reservoir are movable from an expanded position towards to a compressed position and biased to the expanded position for generating a vacuum within the interior. An elongate housing extends along a top side of the reservoir including a passage extending between proximal and distal ends thereof and communicating with the interior of the reservoir. An elongate member extends through the housing including a distal extension, a proximal extension, and a lumen extending therebetween. One-way valves are coupled to the distal and proximal extensions for permitting fluid flow proximally from the distal extension into the interior of the reservoir via and permitting fluid flow proximally from the proximal extension while preventing fluid flow distally out the distal extension and distally into the proximal extension and lumen.

Devices are provided that include a faceplate for a medical device. In embodiments, an identifier chip adapted to be affixed to an exterior portion of a faceplate provides a unique identifier for the faceplate. Accordingly, the identifier chip enables tracking and monitoring of an associated medical device. And, in embodiments, the faceplate includes a visual communication alert indicator to enable the faceplate to provide visual cues a user. As such, the status of the medical device and the faceplate can be easily communicated to the user. Methods to use the faceplate are also provided.