A device for connecting a reservoir to a fluid pathway in a medicament delivery apparatus includes a main body having a service area housing a needle in fluid communication with the fluid pathway. A reservoir is filled with a medicament to be delivered in the fluid pathway through the needle after the latter has pierced an end surface of the reservoir. A plunger is movable within the reservoir along an axial direction parallel to a longitudinal axis of the reservoir, and a piston is movable along said axial direction. A trigger mechanism is configured to drive the device to move from an initial operative configuration at which the axial movement of the piston causes an axial movement of the reservoir with respect to the main body to a final operative configuration at which the axial movement of the piston causes an axial movement of the plunger within the reservoir.

Aspects include systems having an intravenous fluid bag, a tubing line assembly including tubing connected to a connector and a purge valve assembly including a spike and an outer housing. The outer housing is connected to the spike and includes a receiving end portion configured to receive the connector. The purge valve assembly further has a check valve provided within the outer housing. Generally, the purge valve assembly interconnects the fluid bag to the fluid tubing assembly for removal of air from the fluid bag prior to connection to the tubing line assembly. Various methods and purge valve assemblies provide a rapid infusion system for use. The purge valve assemblies do not require the user to reinsert the connector or spike into the intravenous fluid bag, creating a sterile solution to preparing the intravenous fluid for rapid infusion while reducing the risk of air emboli.

Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

A system for delivering an agent to a patient, comprises a delivery device. The delivery device is configured to deliver a first agent to the patient, and comprises a reservoir, a transcutaneous delivery assembly, a pumping mechanism, a control module, a power supply, and a housing. The reservoir stores the first agent. The transcutaneous delivery assembly delivers the first agent to the patient transcutaneously. The pumping mechanism receives the first agent from the reservoir and propels the first agent to the transcutaneous delivery assembly. The control module controls at least the pumping mechanism. The power supply provides energy to at least the control module and the pumping mechanism. The housing surrounds at least the pumping mechanism. Methods of delivering an agent to the patient are also described.

An apparatus and method for delivering liquid to a subject using a pumping device of a flow control apparatus. The method includes recognizing a pump set including a liquid container with a volume of liquid mounted to the flow control apparatus whereby the pump set is positioned to be acted on by the pumping device to deliver aliquots of liquid through the pump set. Operation of the pumping device is initiated to draw a prescribed volume of the liquid from the liquid container for a duration of time. A single aliquot of the volume of liquid is delivered from the liquid container to the subject. Operation of the pumping device is paused for a predetermined period of time before delivering another single aliquot of the volume of liquid from the liquid container to the subject.

Various embodiments are disclosed herein related to fluidic connections for modules useable in combinatorial drug delivery devices. The fluidic connections allow for variable flow paths to be defined for serially-connected, and base-tray mounted, modules.

An administration set, system, and method for administering an infusion fluid for delivering an infusion fluid into a patients anatomic space includes an infusion fluid path having a first portion to connect with a source of the infusion fluid and a second portion to deliver the infusion fluid into the patients anatomic space; and a flow rate sensor disposed in the infusion fluid path between the first and second portion to determine a flow rate measurement of the infusion fluid and to generate a signal indicative of the flow rate measurement to control the flow rate of the infusion fluid through the fluid path.

An administration set, system, and method for administering an infusion fluid for delivering an infusion fluid into a patients anatomic space includes an infusion fluid path having a first portion to connect with a source of the infusion fluid and a second portion to deliver the infusion fluid into the patients anatomic space; and a flow rate sensor disposed in the infusion fluid path between the first and second portion to determine a flow rate measurement of the infusion fluid and to generate a signal indicative of the flow rate measurement to control the flow rate of the infusion fluid through the fluid path.

Various systems and methods for the pressure-regulated transfer of medical fluids are disclosed. The system can include an adapter assembly that connects with a medical container and with a syringe assembly. The syringe assembly can include a first reservoir and a second reservoir. In various embodiments, when the adapter assembly and the syringe assembly are coupled, the first reservoir and the container can exchange regulating fluid and the second reservoir and the container can exchange medical liquid from the medical container.