A syringe-based device for procuring bodily fluid samples can include a housing having a port that can be coupled to a lumen-defining device for receiving bodily fluids, an actuator mechanism including a pre-sample reservoir, a removable plunger cap operably coupled with pre-sample reservoir, a plunger tube, a valve, a plunger seal, and a selectively attachable collection vial for capturing a bodily fluid sample.

A delivery system for the delivery of embolic agents to a patient includes a control valve assembly interconnecting first, second, third and fourth conduits, wherein the control valve assembly selectively moves between first, second, and third states under the control of a medical professional. In the first state, the first conduit communicates with the second conduit for transmitting a solution of embolic agents between a first syringe secured to the first conduit and a second syringe secured to the second conduit. In the second state, the second conduit communicates with the third conduit for transmitting the solution of embolic agents from the second syringe to a delivery catheter secured to the third conduit. In the third state, the third conduit communicates with the fourth conduit for flushing the delivery catheter via a third syringe, which is filled with saline, connected to the fourth conduit.

A method for lubricating an injection needle when used multiple times at a single occasion to penetrate a support, the method including the steps of: a) depositing a layer of a lubricating composition on the support; b) penetrating multiple times the layer of the lubricating composition deposited in step a) with the injection needle, thereby providing a lubricated injection needle having a deposited layer of the lubricating composition thereon.

The present invention provides a drug delivery device (2, 3; 102) for sequential administration of substances, comprising a first variable volume reservoir (40a; 140a) holding a first substance and comprising a first outlet (41 a, 141 a) and a first displaceable wall (43a; 143a), a second variable volume reservoir (40b; 140b) holding a second substance and comprising a second outlet (41 b; 141 b) and a second displaceable wall (43b; 143b), a first wall actuation structure (65a, 70a, 75a, 77a; 177a) activatable to move the first displaceable wall (43a; 143a) and thereby expel a dose of the first substance through the first outlet (41 a; 141 a), a second wall actuation structure (65b, 70b, 75b, 77b; 177b) activatable to move the second displaceable wall (43b; 143b) and thereby expel a dose of the second substance through the second outlet (41 b; 141 b), and a drive structure (90; 190) for activating the first wall actuation structure (65a, 70a, 75a, 77a; 177a) and the second wall actuation structure (65b, 70b, 75b, 77b; 177b). The drive structure (90; 190) performs a predetermined movement during one sequential administration of the first substance and the second substance, the predetermined movement comprising a first part movement followed by a second part movement, and is configured to activate the first wall actuation structure (65a, 70a, 75a, 77a; 177a) during the first part movement and to activate the second wall actuation structure (65b, 70b, 75b, 77b; 177b) during the second part movement.

The present invention concerns an elastomeric stopper (18, 28, 38) for a drug reservoir, comprising: a stopper body (18.1, 28.1, 38.1) extending along a reference axis between a leading end surface (18.2, 28.2, 38.2) and a trailing end surface (18.3, 28.3, 38.3) and having a generally cylindrical sidewall with an outer body diameter, a circumferential convex rib (18.6, 28.6, 38.6) extending radially outwardly from the sidewall, a non-convex trim edge portion (18.7, 28.7, 38.7) at the trailing end surface (18.3, 28.3, 38.3), the non-convex trim edge portion (18.7, 28.7, 38.7) having an outer trim edge diameter which is greater than the outer body diameter and being axially spaced apart from the circumferential convex rib (18.6, 28.6, 38.6), providing an annular recess (18.9, 28.9, 38.9) therebetween. The elastomeric stopper (18, 28, 38) further comprises a channel structure (18.10, 28.10, 38.10) enabling fluid flow from the trailing end surface (18.3, 28.3, 38.3) to the annular recess (18.9, 28.9, 38.9) through the non-convex trim edge portion (18.7, 28.7, 38.7).

Embodiments of the present invention are related to a multichambered syringe including a main body. The main body may include a body first end, a body second end, and a body housing extending from the body first end to the body second end. Within the body housing may be at least one separating member, a plurality of chambers, and a puncture device. The puncture device may be structured to breach the at least one separating member. The puncture device and the at least one separating member may be structured to form a plurality of guided tunnels when the puncture device and the at least one separating member are engaged.

A remote delivery device is provided which has media portholes in a sidewall, a tail piece attached to a rear end and a cannula attached to a front end. The body contains a plunger assembly which defines an injectable liquid chamber and a marking media chamber. The plunger assembly includes a front barbell plunger, rear barbell plunger and a plunger shaft with an O-Ring seated between the front and rear of said plunger shaft. The body also contains a single internal charge positioned behind the plunger assembly. When the charge is activated, the plunger assembly is thrust forwardly and dispenses an injectable liquid from the injectable liquid chamber through the cannula. Simultaneously, the plunger assembly also dispenses a marking media from the marking media chamber through marking media portholes. The provision of a single internal charge allows for a reduction in the length and weight of the device. The single internal charge provides evidence of successful injection of the injectable liquid when the media is displaced from the marking media chamber.

A compartmentalized syringe configured to retain both the medicine and the flushing solution in the same housing. At least one smaller fluid or solid containing container will be added inside the flush housing and will separate its content(s) from other fluids or solids inside the flush housing. The shape of the housing and inner containers can be similar with the outer syringe flush with channels to facilitate the flow of fluids and they can also be of different shapes which will automatically create channels to allow the flow of fluid. An opening in the syringe plunger configured to receive a medicine vial.

A syringe-based device includes a housing and an actuator mechanism including a first member and a second member. The first member includes a syringe body and a plunger, the plunger being movably disposed within the syringe body. The second member includes a second member plunger seal and a valve operably and selectively coupled to the second member plunger seal such that the valve is positioned proximal of the second member plunger seal. The device also includes a first fluid reservoir and a second fluid reservoir. The device transitions from a first configuration to a second configuration in which the first type of fluid is expelled from the first fluid reservoir, to a third configuration in which the second type of fluid is expelled from the second fluid reservoir through the valve.

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior.