Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof.

A method for distracting an individual from a treatment event comprises providing a distraction tool; positioning the distraction tool at a contact location on an individual, the contact location being substantially adjacent a location of a treatment event; activating an oscillation device to induce vibrations in the distraction tool; and subsequently initiating the treatment event at the treatment event location. The distraction tool comprises a stimulation apparatus comprising a housing and a plurality of projections extending from the housing. The oscillation device is in communication with the distraction tool to induce vibrations specifically in the stimulation apparatus. Activating the oscillation device to induce vibrations causes the plurality of projections to oscillate against the individual at the contact location, thereby shifting attention from the treatment event to the vibrations, wherein the shift in attention causes the individual to discount pain caused by the treatment event.

The present invention relates generally to a warming apparatus such as but not limited to a sleeve with an attached tourniquet that allows for a method of warming human body parts and a method to induce vasodilation to produce the ease of venipuncture. The invention preferably induces vasodilation by applying heat to an area and then further where venipuncture or intravenous catheter insertion is desired, preferably constricting and compressing the veins by bringing them to the surface with the tourniquet.

A means and a method is disclosed to diminish or eliminate the pain associated with a sharp object penetrating the skin, during such procedures as an injection, biopsy, or deriving a blood sample. To this end, repeated tapping, pressing, or rubbing is performed over the skin at or near the site of penetration of the sharp object in conjunction with applying electricity on the skin. The invention discloses a method of using a skin-puncturing means, with enhanced features, to provide local anesthesia at the site of penetration of a sharp object.

The various embodiments disclosed herein are devices that deliver electrical stimulation and/or vibration stimulation to the surface of skin in proximity to insulin injections and/or glucose testing in order to decrease or eliminate the pain of these procedures.

A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.

Delivery devices for administering drugs are disclosed. An example apparatus, includes a body including: a handle in which a syringe assembly is to be disposed; a base having a bottom face to be disposed adjacent a user; and an absorbent material attached to the bottom face, the absorbent material structured to hold a fluid to be released onto the user prior to or during an injection procedure.

A multifunctional microstructure patch is provided. The multifunctional microstructure patch, according to one embodiment of the present invention, comprises: a base layer having an opening part formed in the center thereof; a plurality of microstructures formed on one surface of the base layer and comprising a first drug; and a cover layer detachably bonded on the other surface of the base layer along the periphery of the opening part, and formed so as to cover the opening part.

A means and a method is disclosed to diminish or eliminate pain associated with a sharp object penetrating skin, during such procedures as an injection, biopsy, or deriving a blood sample. To this end, repeated tapping, pressing, or rubbing is performed over the skin at or near a site of penetration of the sharp object in conjunction with applying electricity on the skin. The invention discloses a method of using a syringe or a lancet, with enhanced features, to provide local anesthesia at a site of penetration of a sharp object.