Systems, devices, and methods are provided for transseptal access of septa within a patient. The device can be advanced to a septum, e.g., towards a fossa ovalis. Instead of applying positive pressure to “tent” the septum, a negative pressure is applied to a lumen within a sheath, e.g., within an elongated member slidable within the sheath, via a negative pressure source such as a syringe on the proximal end of the sheath. This results in the septum pulling inward. The sheath employs a stationary needle-like central core component contained within the lumen of the sheath that punctures the septum when the same is pulled passed it by the negative pressure. The stationary needle-like central core component may be hollow and may form a portion of the elongated member or may be coupled to a distal end thereof.

A time saving sit on cardio pulmonary resuscitation device and method wherein the said device for providing cpr is adopted with an arrangement to seat a person and enable the start of cpr within five minutes of a heart attack affecting a patient, comprising of a reciprocating resuscitation force applicator where a counter force to the reactive force arising on applying compression force for resuscitation, said counter force being provided by the weight of a person sitting on the seating means and a belt based drive conveyance means forming a loop from top of a enclosure box allowing cpr without latching. A very clearly understandable, unambiguous, two step method of sitting on the device placed around the patient body, no confusion, no decision steps, no mental thinking on what to do. The device takes care of most decisions automatically.

A phlebotomy aid provides a capability to expand circulatory members for emphasizing venous appearance and accessibility on an epidermal surface. A warming sheath or sleeve extends over a patient forearm for introducing a thermal source adjacent to a patient blood vessel for emphasizing the vein appearance on the epidermal surface. A beating element in the sleeve is powered and controlled by a low voltage circuit for controlled thermal introduction for mitigating discomfort from overheating and eliminating proximity of potentially harmful electrical exposure.

Various implementations include a tissue lifting device that is operable using one hand. The device includes a housing, an actuator that is slidably moveable through a channel within the housing, and a lifting mechanism adjacent a distal end of the housing. The actuator causes the lifting mechanism to lift a tissue. In some implementations, the housing includes a needle adjacent the distal end of the housing that punctures the tissue and allows for injection of a composition behind the tissue. The lifting mechanism according to some implementations is a suction-based (or aspiration) system. And, in other implementations, the lifting mechanism is a grasping system.

A system to facilitate a syringe injection, the system including a skin clamping device, including a first clamp assembly, a second clamp assembly, a joint to connect a center portion of the first clamp assembly to a center portion of the second clamp assembly, such that the first clamp assembly and the second clamp assembly move with respect to each other, and pinch skin of a patient therebetween, a spring disposed between the first clamp assembly and the second clamp assembly to keep the first clamp assembly away from the second clamp assembly, and a hydraulic assembly disposed on at least a portion of the spring and connected to a syringe to compress away from the spring in response to the first clamp assembly moving at least partially toward the second clamp assembly, and decompress toward the spring in response to the first clamp assembly moving at least partially away from the second clamp assembly, and a limb holder to receive a limb of the patient therein.

Systems, devices, and methods are provided for transseptal access of septa within a patient. The device can be advanced to a septum, e.g., towards a fossa ovalis. Instead of applying positive pressure to “tent” the septum, a negative pressure is applied to a lumen within a sheath, e.g., within an elongated member slidable within the sheath, via a negative pressure source such as a syringe on the proximal end of the sheath. This results in the septum pulling inward. The sheath employs a stationary needle-like central core component contained within the lumen of the sheath that punctures the septum when the same is pulled passed it by the negative pressure. The stationary needle-like central core component may be hollow and may form a portion of the elongated member or may be coupled to a distal end thereof

An autoinjector including a syringe, a driver for driving the plunger of the syringe and a stabilizing adaptor for holding the injector on the skin of a patient is provided. The stabilizing adaptor has an adhesive base with a long axis to short axis ratio of at least 1.5 to 1. The syringe is orientated with its axis at an angle of between 60 and 120 degrees to the base during operation of the autoinjector.

The invention relates to a needle delivery device comprising a device body; one or more skin pinching members attached to the device body, the skin pinching members being moveable to pinch a longitudinal fold of skin of a patient. The device also comprises a drive mechanism configured to drive a needle out of the device body and along a needle path into the longitudinal fold of skin pinched between the pinching members, and subsequently withdraw the needle, the needle path extending substantially parallel to the surface of the patient.

The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

An administration device including a needle; a cartridge which is capable of storing a liquid medicine to be administered into a living body by the needle; a case which has an open or openable first end to be pressed against the skin, and in which the needle and the cartridge are stored in such a manner as to be movable toward the first end side, the needle being capable of moving to the outside of the first end in response to the movement of the needle toward the first end ide; and a pressing force control member which intervenes so as to generate a reactive force between the cartridge and the case and which controls a pressing force exerted on the skin by the case while the needle moves toward the first end side. In the process of piercing by the needle, a reactive force is continuously generated by the pressing force control member and the pressing force exerted on the skin by the case is controlled at a substantially constant level, whereby the piercing depth by the needle is kept substantially constant at the time of completion of the piercing by the needle; and in the process of discharging the liquid medicine stored in the cartridge through the needle for administration, the reactive force by the pressing force control member is generated continuously, whereby the piercing depth by the needle is kept substantially constant.