The invention relates to a needle delivery device comprising a device body; one or more skin pinching members attached to the device body, the skin pinching members being moveable to pinch a longitudinal fold of skin of a patient. The device also comprises e a drive mechanism configured to drive a needle out of the device body and along a needle path into the longitudinal fold of skin pinched between the pinching members, and subsequently withdraw the needle, the needle path extending substantially parallel to the surface of the patient.

A vein stabilizer device for venipuncture procedures is provided. The vein stabilizer device is embodied in an elongated body providing an external stabilizer tip protruding from a distal end of the body. The stabilizer tip may be defined by a supratip break, an infratip break, and two lateral breaks. Surface area of the breaks are dimensioned and adapted to engage the skin of a patient so as to stabilize a vein therein. The elongated body has a cavity for slidably receiving a finger of a user in such a way that the user can selectively apply pressure through a chosen break surface.

A method and system of providing a needle-less injector specifically configured to the needs of a user. The method includes assembling a needle-less injector by positioning an inner housing within the outer housing such that the inner housing is axially movable within the outer housing between a ready position and a firing position. The method further includes receiving a user selection of a delivery spring weight from a plurality of available delivery spring weights. Then a delivery spring having the selected spring weight is placed within the inner housing. The completed needle-less injector having a delivery spring with the selected weigh may then be delivered to the user. In alternative injector configurations, the user may also select one or more of a skin tensioning spring weight or a hammer length along with or instead of the delivery spring weight.

A needleless injector configured to inject an injection intended substance to an injection target region, by injecting the injection intended substance includes a nozzle portion and a pressing portion, and a predetermined gap is formed between the nozzle portion and the pressing portion. The nozzle portion is formed to have a portion of the distal end portion that comes into contact with the injection target region and has a width (a) falling within a range from 3.5 mm to 5.5 mm, and a ratio (b/a) defined by an inner diameter (b) of a portion of a distal end portion of the pressing portion that comes into contact with the injection target region by the width (a) falls within a range from 1.5 to 5.0. A part of the injection target region is received in the predetermined gap when the pressing portion presses the injection target region.

A needle tube having a needle tip for puncturing skin; a needle hub; and a fluid-draining portion for enabling draining of a medicine. The needle hub includes: a retention part (first member) for retaining the needle tube; an insertion part into which the output portion of a syringe is inserted; and a flange-like skin contact portion that is disposed in a manner so as to cover an area surrounding the needle tube and makes contact with and/or faces the skin when a living body is punctured with the needle tube. The fluid-draining portion is disposed in the skin contact portion of the needle hub and enables a user to drain the medicine that has spilled when removing air and is held in the skin contact portion.

A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.

Systems, devices, and methods are provided for transseptal access of septa within a patient. The device can be advanced to a septum, e.g., towards a fossa ovalis. Instead of applying positive pressure to tent the septum, a negative pressure is applied to a lumen within a sheath, e.g., within an elongated member slidable within the sheath, via a negative pressure source such as a syringe on the proximal end of the sheath. This results in the septum pulling inward. The sheath employs a stationary needle-like central core component contained within the lumen of the sheath that punctures the septum when the same is pulled passed it by the negative pressure. The stationary needle-like central core component may be hollow and may form a portion of the elongated member or may be coupled to a distal end thereof.

A transdermal drug delivery device is disclosed that may comprise a housing including an upper housing portion and a lower housing portion. The lower housing portion may define a bottom surface including skin attachment means for releasably attaching the lower housing portion to skin of a user. The upper housing portion may at least partially surround a central region of the device. The device may also include a microneedle assembly and a reservoir disposed within the central region. The reservoir may be in fluid communication with the microneedle assembly. Additionally, the device may include a pushing element disposed above the microneedle assembly within the central region. The pushing element may be configured to provide a continuous bilateral force having a downward component transmitted through the microneedle assembly and an upward component transmitted through the skin attachment means.

Devices, methods, and systems are provided for placing an implant into a patient and removing it therefrom.

A device for pinching a user's skin includes a first head member including a handle portion, a jaw portion, and an intermediate portion therebetween, the handle portion having a terminal end with an engagement means; a second head member including a handle portion, a jaw portion, and an intermediate portion therebetween, the handle portion having an elongated end with a generally arcuate translating rack with a corresponding engagement means; and pivot means on the intermediate portions permitting the jaw portions to converge on the skinfold and grasp the skinfold in response to initial movement of the handle portions toward each other.