An assistive device for subcutaneous injections or implants. The assistive device is placed under a blood pressure cuff that displaces the skin and subcutaneous tissues of a patient at an insertion site in order to allow guided insertion of a needle or implant applicator into a subcutaneous fat layer. The skin and subcutaneous tissue is displaced or drawn, via pressure applied by the blood pressure cuff, through an injection window of a device body into a hollow cavity of the device body. A guide channel leads from a front side of the device body into the hollow cavity, and an applicator of an adapter is inserted through the guide channel into the subcutaneous fat layer.

A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.

The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

A two-stage infusion set inserter system is disclosed. The inserter system includes an inserter assembly including a housing including a rotatable button assembly comprising ramps and and tab indents and a non-rotatable portion of housing, a sliding component comprising sliding component tabs, a needle carrier connected to an introduction needle, the needle carrier slidably movable from a starting position to an injection position and then to a second ending position, a sliding component spring, and a needle spring, wherein the rotatable button assembly rotates from a locked to an unlocked position, wherein when force is applied onto the rotatable button assembly, the sliding component and needle carrier are forced downward by the sliding component spring, and wherein when the needle carrier reaches the injection position, the needle spring forces the needle carrier upward towards the second ending position.

Various implementations include a tissue lifting device that is operable using one hand. The device includes a housing, an actuator that is slidably moveable through a channel within the housing, and a lifting mechanism adjacent a distal end of the housing. The actuator causes the lifting mechanism to lift a tissue. In some implementations, the housing includes a needle adjacent the distal end of the housing that punctures the tissue and allows for injection of a composition behind the tissue. The lifting mechanism according to some implementations is a suction-based (or aspiration) system. And, in other implementations, the lifting mechanism is a grasping system.

An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

A device for delivering a fluid into a biological tissue includes hollow microneedles (10) projecting from a surface (12) of a substrate (14), and a guide element (18) spaced from the substrate. The guide element provides a tissue-contact surface (20) that defines a tissue contact plane oblique to the surface (12) of the substrate (14).

An intradermal injection needle is an intradermal injection needle assembly to be used by piercing the intradermal injection needle into the skin of a living body. The intradermal injection needle has a hollow needle having a blade edge pierceable into the skin and a discharge port of an administration product; and a hub holding the hollow needle. The hollow needle has an outer diameter of 0.15 to 0.20 mm. The discharge port has a length of 0.10 to 0.80 mm in an axial direction of the hollow needle. When the intradermal injection needle is pierced into the skin of the living body, the discharge port thereof is entirely subcutaneously pierceable within a range of 0.20 to 1.00 mm.

The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.

Poultry injection apparatus with rotating capture members and methods of using the same are described herein. Each injection apparatus may include one or more rotating capture members and an injection unit configured to move an injection needle between an injection position and a retracted position relative to the one or more capture members.