Dose delivery device with partially or fully surrounding cover may be removed to open fluid communication with a dose chamber. The cover may allow an inhaler to be stored in sterile or otherwise in a controlled environment prior to use, and removal of the cover may automatically prepare the inhaler for use.

A nasal delivery device for and a method of delivering substance to a nasal airway of a subject, the nasal delivery device including a mouthpiece (519) through which the subject in use exhales to cause closure of the oropharyngeal velum of the subject; a nosepiece (517) for fitting to a nostril of a subject, the nosepiece including a nozzle (549) through which the substance is in use delivered to the nasal airway; and a manually-actuatable substance supply unit (520) for delivering substance through the nozzle of the nosepiece.

A nasal delivery device for and a method of delivering substance to a nasal airway of a subject, the nasal delivery device including a mouthpiece (519) through which the subject in use exhales to cause closure of the oropharyngeal velum of the subject; a nosepiece (517) for fitting to a nostril of a subject, the nosepiece including a nozzle (549) through which the substance is in use delivered to the nasal airway; and a manually-actuatable substance supply unit (520) for delivering substance through the nozzle of the nosepiece.

An apparatus for filling a cartridge with medical gas, comprising a sealing mechanism designed to removably seal against the open end of an uncapped and empty cartridge, evacuate the cartridge, producing at least a partial vacuum therein, fill the cartridge with medical gas at a predetermined pressure and temperature, and maintain the predetermined pressure and temperature while the cartridge is capped is presented.

An essential oil diffusion mechanism, including: a housing having an accommodation chamber; and a separator that divides the accommodation chamber into an upper chamber and a lower chamber and includes a horizontal partition plate and vertical partition plates. The horizontal partition plate defines at least one interconnecting hole. An upper surface of each vertical partition plate is spaced apart from a chamber wall of the upper chamber to form an upper interconnecting aperture. Each vertical partition plate defines an interconnecting reflux hole. A lower surface of each baffling plate is spaced apart from the horizontal partition plate to form a lower interconnecting aperture. The interconnecting hole, the upper interconnecting aperture, the lower interconnecting aperture, and the air outlet are sequentially arranged in communication to form an air outlet channel. The upper interconnecting aperture, the reflux hole, and the interconnecting hole are sequentially arranged in communication to form a reflux channel.

An electronic cigarette including an atomization assembly and a base assembly. The atomization assembly includes a mouthpiece; a first seal ring; a first seal cover; an airflow regulation ring; a permanent seat; an O-shaped ring; an atomizer; a second seal ring; a funnel; a third seal ring; a spring; an e-liquid injector; a fourth seal ring; a second seal cover; a fifth seal ring; a press cover; a positive terminal; a first silicone pad; a connection cylinder; a cover plate; a sixth seal ring; an e-liquid tank; a seventh seal ring; a negative terminal; a first circular magnet; a first strip magnet; and a magnet cover. The battery assembly includes: a second circular magnet; a second strip magnet; a housing; a front cover plate; a press button; a back cover plate; a silicone plug; a battery; a control plate; a second silicone pad; and a LED cover.

The present invention provides an aerosol device for delivering a pharmaceutical formulation by inhalation via the mouth to the lungs or to the nostril in metered doses comprising: a pressurised aerosol canister including a vial containing a pharmaceutical formulation comprising an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further comprising a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a delivery outlet and a stem block, the stem block having a receptacle into which the valve stem of the metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice arranged to direct the pharmaceutical formulation through the delivery outlet, a transfer tunnel having an input opening and an output opening through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice, and a land length defining the distance from between the input opening and output opening, wherein the input opening and the output opening have cross-sectional areas of from 0.002 to 0.8 mm.sup.2 and the cross-sectional area of the input opening is smaller than the cross-sectional area of the output opening, and wherein the land length is from 0.5 mm to 10 mm.

The present invention provides an aerosol device for delivering a pharmaceutical formulation by inhalation via the mouth to the lungs or to the nostril in metered doses comprising: a pressurised aerosol canister including a vial containing a pharmaceutical formulation comprising an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further comprising a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a delivery outlet and a stem block, the stem block having a receptacle into which the valve stem of the metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice arranged to direct the pharmaceutical formulation through the delivery outlet, a transfer tunnel having an input opening and an output opening through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice, and a land length defining the distance from between the input opening and output opening, wherein the input opening and the output opening have cross-sectional areas of from 0.002 to 0.8 mm.sup.2 and the cross-sectional area of the input opening is smaller than the cross-sectional area of the output opening, and wherein the land length is from 0.5 mm to 10 mm.

This disclosure describes example antimicrobial compositions that may be used in combination with IV port cleansing caps, protective caps, or nasal decolonizer devices. According to another implementations, the disclosure describes that the antimicrobial composition may provide an indication that it has come into contact with a contaminant by bubbling or foam on a surface that is being cleaned. According to another implementation, the disclosure describes that the antimicrobial composition may leave a residual film or barrier to inhibit the recontamination of a surface that has been cleaned.

This disclosure describes example antimicrobial compositions that may be used in combination with IV port cleansing caps, protective caps, or nasal decolonizer devices. According to another implementations, the disclosure describes that the antimicrobial composition may provide an indication that it has come into contact with a contaminant by bubbling or foam on a surface that is being cleaned. According to another implementation, the disclosure describes that the antimicrobial composition may leave a residual film or barrier to inhibit the recontamination of a surface that has been cleaned.