A stand-alone chamber or multi-chamber inhalation system has at least two alternative vaporized test liquid supply systems for passive or self-administered delivery of vaporized test fluid and air to one or more test chambers, which can be passive or restraint chambers, based on operator selection of delivery on and off times in a passive mode or actuation of an actuator in the chamber by a test animal in a self-administered mode. In one case, a multiple inhalation chamber system has two or more separate test fluid delivery systems and provides options for selective passive uniform drug delivery to multiple chambers or selective delivery of two or more different drugs to different groups of chambers from different delivery systems so that two different drugs or different concentrations of delivered drugs can be tested simultaneously.

An apparatus for humidification of air to be delivered to a patient's airways may include a reservoir, and a humidifier chamber. The humidifier chamber may include a humidifier wick and a heating element for heating the humidifier chamber. The humidifier wick may comprise a fibrous sheet material. The humidifier chamber and wick may be vertically oriented in use such that a first end of the wick is above the second end of the wick. A deioniser may be provided to deionise the liquid prior to the humidifier wick. The apparatus may pasteurise liquid to be delivered to the humidification wick.

A fragrance suitable for a user can be provided. A mobile terminal includes: an acquisition unit that acquires a psychosomatic state from a physiological index of a user; an input unit that inputs future information of the user; a determination unit that determines a recipe including one or more types and a mixing ratio of one or more perfumes based on the psychosomatic state and the future information; and a communication unit that transmits the recipe to a fragrance generation device.

An arrangement for an inhaler comprises at least one electric evaporator for evaporating liquid supplied from the evaporator, and for adding the evaporated liquid to an air flow flowing through the inhaler to form an aerosol, and a flow rate measuring arrangement for measuring the volume and/or mass flow of the air flow flowing through the inhaler. The flow rate measuring arrangement comprises a heating device, a downstream temperature sensor arranged downstream of the heating device for measuring an air outlet temperature and an electronic control device, wherein the electronic control device is adapted to determine the volume and/or mass flow of the air flow flowing through the inhaler on the basis of a temperature difference between the air outlet temperature and an air inlet temperature of the air flow upstream of the heating device.

Provided is a blister pack for a dry powder inhaler, which dry powder inhaler is configured to deliver a first powder medicament and a second powder medicament different from the first powder medicament. The first and second powder medicaments are contained within blister pockets defined in a strip. A series of blister pockets is defined in the strip, which series extends linearly along the length of the strip. The first and second powder medicaments are contained in blister pockets, e.g. respective blister pockets, of the series. Alternatively or additionally, each of the blister pockets is elongated such as to have a largest dimension parallel with the length of the strip. These measures, either individually or in combination, enable minimizing of the width of the strip in spite of the strip accommodating both the first and second powder medicaments. This, in turn, may enable the depth/thickness of the dry powder inhaler to be minimized, and/or additional space to be provided inside the dry powder inhaler for accommodating, for example, use detection and wireless connectivity electronics for sending use detection data to an external device, such as a smartphone.

Disclosed are dry powder inhalers for delivering medicament to a user from a blister pack, the blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhalers comprise: a housing for accommodating unused and used portions of the blister pack together with a dispensing mechanism for selectively opening the blister pockets; and a manifold component through which air can be drawn in use of the inhaler. The manifold component comprises: a primary air inlet opening for receiving first external air; an air outlet opening for providing the external air from the primary air inlet opening into an opened blister pocket, the primary air inlet opening being fluidly connected to the air outlet opening by a primary air delivery conduit formed in the manifold component; a medicament inlet opening for receiving air-entrained medicament from the opened blister pocket, the air outlet opening and the medicament inlet opening being arranged side-by-side to enable simultaneous communication with the opened blister pocket; and a medicament outlet opening for delivery of the air-entrained medicament from the opened blister pocket to the user, the medicament inlet opening being fluidly connected to the medicament outlet opening by a medicament delivery conduit formed in the manifold component. The disclosed inhalers embodiments provide a variety of improvements to the design of the manifold component.

Disclosed is a dry powder inhaler for delivering medicament from at least one blister pack, each blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhaler comprises: a housing for accommodating unused and used portions of the at least one blister pack together with a dispensing mechanism for simultaneously opening at least two blister pockets at a time; and a manifold component through which air can be drawn in use of the inhaler. The manifold component comprises: first and second air inlet openings for receiving external air a first air outlet opening for providing the external air to a first opened blister pocket and a first medicament inlet opening for receiving air-entrained medicament from the first opened blister pocket, the first air outlet opening and the first medicament inlet opening being arranged side-by-side to enable simultaneous communication with the first opened blister pocket; a second air outlet opening for providing the external air to a second opened blister pocket and a second medicament inlet opening for receiving air-entrained medicament from the second opened blister pocket, the second air outlet opening and the second medicament inlet opening being arranged side-by-side to enable simultaneous communication with the second opened blister pocket; and a medicament outlet opening for delivery of the air-entrained medicament from the first and second opened blister pockets to the user, the first and second medicament inlet openings being fluidly connected to the medicament outlet opening by a medicament delivery conduit formed in the manifold component. The first and second air inlet openings are fluidly connected to the first and second air outlet openings by respective first and second air conduits in the manifold component, wherein the air conduits are separately provided so that the external air from each of the first and second air inlet openings does not mix with the external air from the other of the first and second air inlet openings before reaching the first and second opened blister pockets.

Systems and methods are provided for delivering one or more drugs. In some embodiments, a drug delivery system includes a housing having a distal end with an inlet through which an inspiratory flow of air passes into the housing, a proximal end having a patient interface attached thereto, the patient interface being configured to interface with a user, and an inspiratory flow pathway extending from the distal end to the proximal end of the housing. A nitric oxide (NO) source is positioned within the housing and is configured to deliver NO-containing gas to the patient interface. A secondary drug source is positioned within the housing and is configured to deliver a secondary drug to the patient interface. A controller is configured to control an amount of NO-containing gas and an amount of the secondary drug delivered using a control scheme.

A microfluidic dispenser device of inhalable substances includes a casing, housed in which are a driving circuit and a microfluidic cartridge having a tank that contains a liquid to be delivered. The microfluidic cartridge is provided with at least one nebulizer controlled by the driving device. The nebulizer includes: a substrate; a plurality of chambers formed on the substrate and fluidically coupled to the tank for receiving the liquid to be delivered; and a plurality of heaters, which are formed on the substrate in positions corresponding to respective chambers, are thermally coupled to the respective chambers and are separated from the respective chambers by an insulating layer, and are controlled by the driving device. Each chamber is fluidically connected with the outside by at least one respective nozzle.

An aerosol-generator for an aerosol-generating device is provided, including: a surface acoustic wave atomiser including: a substrate including an active surface defining an atomisation region, first and second transducers positioned on the active surface; first and second supply elements to respectively supply first and second liquid aerosol-forming substrates to the atomisation region; a controller to provide first and second drive signals respectively to the first and the second transducers to generate surface acoustic waves on the active surface, provide the first drive signal only when the first substrate is supplied to the atomisation region by the first supply element, and provide the second drive signal only when the second substrate is supplied to the atomisation region by the second supply element. An aerosol-generating device including the aerosol-generator is also provided.