A nosepiece for delivering substance to a nasal cavity of a subject, the nosepiece comprising a body part which comprises a base portion which defines a flow passage therethrough, and a projection at a distal end of the base portion which at least in part provides a tip of the nosepiece and confers a rigidity in the sagittal direction, which enables the tip to open fleshy tissue at an upper region of the nasal valve and thereby expand an open area of the nasal valve, and a flexibility in a lateral direction, orthogonal to the sagittal plane, which facilitates insertion of the tip into the nasal valve.

A therapeutic device for treating one or more conditions associated with a user's nasal cavities, sinuses, and/or ear canals includes a vibration generator having an acoustic device operable to provide a sound; a seal configured to cover a nose, but not a mouth, of the user to form an air-tight chamber around the nose of the user; the vibration generator disposed in a housing connected to the seal; and a stand extending from the housing and including a ball bearing and a seat on which the ball bearing may rest, the stand including a hollow member and an orifice, the orifice disposed in the seat. The vibration generator provides the sound directly to the nose of the user. A positive pressure is created in the air-tight chamber when the user exhales, the positive pressure generating a lift force to lift the ball bearing from the seat.

A vaporizer device may include a plurality of cartridges with a plurality of aerosolization assemblies. The plurality of cartridges may include a suspension media and an additive media. The plurality of aerosolization assemblies may include pressurized cartridges connected to a nozzle having a nozzle opening of less than 20 micrometers.

Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges comprising at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.

A delivery device for and method of modulating a condition relating to sodal cognition and/or behaviour in a human subject using oxytocin, non-peptide agonists thereof and/or antagonists thereof, comprising: providing a nosepiece to a first nasal cavity of the subject; and providing a supply unit for administering less than 24 IU of oxytocin, non-peptide agonists thereof and/or antagonists thereof through the nosepiece to an upper region posterior of the nasal valve which is innervated by the trigeminal nerve.

The present invention provides disposable capsules and electronic inhalers designed to be used therewith, and to methods for consuming cannabis in a clean, simple and efficient way, which is also cost effective.

An inhalation-synchronized fluid dispenser device having a body (10; 10′) provided with a mouthpiece (400), a fluid reservoir (100) containing a fluid and a propellant gas being mounted to slide axially in the body (10; 10′), a metering valve (200) including a valve member (210) assembled on the reservoir (100) for selectively dispensing the fluid. The device includes an actuator element (500, 500′, 500″; 550) movable and/or deformable between a non-actuation position and an actuation position; an inhalation-controlled trigger system including an inhalation-sensitive member (60, 61; 65, 66) deformable and/or movable under the effect of inhaling and when deformed and/or moved, moving and/or deforming the actuator element (500, 500′, 500″; 550) from its non-actuation position towards its actuation position; an electronic dose counter (1000); and a signal-transmitter (1100) for communicating, in particular communicating remotely, information relating to the actuations of the device.

An inhalation-synchronized fluid dispenser device having a body; a mouthpiece; a reservoir; a valve; a blocking element; a trigger element; and an inhalation-controlled trigger system including an inhalation-sensitive member deformable or movable so that when the inhalation-sensitive member is deformed and/or moved, it moves and/or deforms the trigger element towards its release position, thereby making it possible to move and/or deform the blocking element towards its actuation position. The device has a ring that co-operates with the blocking element, such that in the blocking position, an axial projection of the ring co-operates with an axial blocking extension so as to block the reservoir, and in the actuation position, the axial projection co-operates with an axial recess, thereby enabling the reservoir to move axially.

A mobile inhaler is configured to provide an inhalable aerosol to a user. The mobile inhaler may include a vibrating mesh atomizer. The vibrating mesh atomizer may include a vibrating mesh membrane comprising a plurality of holes, a piezoelectric actuator coupled to the vibrating mesh membrane, wherein the processing equipment is configured to actuate the piezoelectric actuator, and a vibrating mesh membrane holder. The mobile inhaler includes processing equipment, which may include memory configured to store information about one or more users, including usage behaviour. A capsule is used to hold liquid for atomizing and may include a plunger to dispense liquid. The processing equipment may be configured to determine desired dosages, or other desired usage metrics, based on the stored information. In some embodiments, information from a plurality of mobile inhalers may be stored and analysed.

The invention relates to a nebulization device (1) for medical mixture, of the type comprising: a containing ampoule (2) for medical mixture, comprising an upper component (2a) and a lower component (2b) connected to each other; at least one emission opening (11) of said nebulized medical mixture from the ampoule (2), and at least one entry window (19) for the intake of air within said ampoule (2); as well as at least one atomizer (14) for the intake of pressurized gas, within the lower component (2b) of the ampoule (2), the atomizer (14) being surmounted by the upper component (2a). Advantageously, at least one, preferably two selection side windows (24) are provided on the upper component (2a), the opening of said selection side windows (24) being shielded by shielding means (16), moved by a command shaft (17).