The invention is directed to an inhaler device for inhalable liquids, in particular for the administration of inhalable volatile liquids such as halogenated volatile liquids, to a patient. According to particular embodiments, the inhaler device may include a liquid container for hermetically storing inhalable liquid; a wicking material for supporting inhalable liquid; a piercing member configured to pierce the liquid container, wherein the liquid container may be provided in a first position in which the piercing member does not engage the liquid container and inhalable liquid remains hermetically stored within the liquid container, and the liquid container may be displaced from the first position to a second position such that the piercing member pierces the liquid container to release inhalable liquid onto the wicking material, whereby during inhalation inhalable liquid vapor from the wicking material is delivered to the patient.

An infectious aerosol capture mask (IACM) includes a face tent coupled to a suction tube adapter. The face tent includes a proximal opening configured to be disposed over the mouth and nose of a patient. The face tent further includes a distal opening with a smaller diameter than the proximal opening. A coupler is configured to secure the suction tube adapter to the distal opening of the face tent. The suction tube adapter includes a suction port configured to be coupled to a suction tube for active capture of infectious aerosol and left unconnected for passive capture of infectious aerosol. A viral filter is disposed between the suction port and the face tent to capture infectious aerosols expelled by the patient. The IACM further includes one or more one-way valves that are configured to permit airflow into the face tent.

Containment units, dry powder inhalers, delivery systems, and methods for the same are disclosed. Exemplary devices are configured to have inlets and outlets which are formed with the containment walls of a containment unit. Air jets formed by the configuration of inlet(s) and outlet(s) inside the containment unit create significant turbulence and deaggregate the powder. Delivery system components downstream of the containment unit may integrate the exiting aerosol plume with a low flow nasal cannula air stream for delivery to a subject.

An electronic device for producing an aerosol for inhalation by a person includes a mouthpiece, a liquid container, and a mesh assembly having a mesh material and a piezoelectric material. The mesh material is in contact with a liquid of the container. The mesh material is configured to vibrate when the piezoelectric material is actuated, whereby the aerosol is produced. The aerosol may be inhaled through the mouthpiece. The device also includes circuitry and a power supply for actuating the mesh assembly. The mouthpiece, the container, and the mesh assembly are located in-line along a longitudinal axis of the device between opposite longitudinal ends of the device, with the mesh assembly extending between and separating the mouthpiece and the container. The mesh material has a rigidity that is sufficient to prevent oscillations of varying amplitudes during actuation of the piezoelectric material of the mesh assembly for consistently producing the aerosol.

Kits enabling an end user to efficiently compound inhalable formulations containing medicinal compounds, for use in in aerosol device (e-cigarette; personal vaporizer). Kits include a reusable storage device, a filling station, at least one predetermined amount aerosol precursor in a container and at least one empty cartomizer (cartridge) for use in an aerosol delivery device. Optionally, kits may also include a predetermined amount of extract containing a known amount of medicinal compound, enabling the production of an amount an inhalable formulation. Optionally, kits may contain amounts of inputs that enable the refilling/reuse of cartridges.

A dry powder inhaler includes a powder storage element configured to hold a powdered medicament and an inlet channel receives, powdered medicament from the powder storage element that is entrained in an airflow. The inlet channel has a first diameter and defines an opening. The inhaler includes a dispersion chamber that receives the airflow and the powdered medicament from the opening. The dispersion chamber has a second diameter. The inhaler includes an actuator housed within the dispersion chamber. The actuator oscillates within the dispersion chamber when exposed to the airflow to deaggregate the powdered medicament entrained by the airflow passing through the dispersion chamber. A ratio between the first diameter and the second diameter is between about 0.40 and 0.60 such that an audible sound is produced as the actuator oscillates. The inhaler includes an outlet channel through which the airflow and powdered medicament exit the inhaler.

The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

Exemplary dry powder inhaler devices may include a housing body having a medicine capsule recess therein, a pair of air inlets each fluidically connecting to the recess, and an outlet body coupled to the housing body. Each inlet may have a width no greater than 1.17 mm. The outlet body may have a channel fluidically connecting the recess to an opening and configured to allow a user to draw air through the opening, thereby allowing an airstream to be drawn through the air inlets, into the housing body recess where it causes the capsule to spin and eject its contents into the airstream, and through the outlet body channel and opening to deliver the substance into the user's lungs. Dry powder respirable drug blend formulations, methods of manufacturing the formulations and drug/device combinations are also provided.

A system for delivering a composition containing a nutritional supplement matrix to a user through the oral mucosa, in which the matrix is held under pressure in a canister that has a nozzle with at least one rotating internal member positioned between the canister outlet and the nozzle outlet, in which the rotating member agitates the composition to increase atomization to aid in absorption.

A water bottle with a pressurized compartment and an unpressurized compartment to integrate supplemental oxygen delivery into a hydration and electrolyte management system. The unpressurized compartment may be manually filled with a fluid. The user may consume fluid from the unpressurized compartment and an aerosol from the pressurized compartment independently or simultaneously.