An aerosol generation device comprises a chamber, a housing and a cover. The chamber is adapted to receive a consumable. The housing contains the chamber and comprises an opening through which the consumable can be removed from the chamber. The cover is configured to move between an open position where the opening of the housing is exposed and a closed position where the opening of the housing is closed. The aerosol generation device is adapted to generate an inhalable vapor from the consumable. The cover comprises one or more dislodging elements adapted to dislodge the consumable such that, when the cover moves from the closed position to the open position: an attachment is weakened between the chamber and the consumable, and the consumable is partially ejected from the chamber without becoming attached to the cover.

In general, drug administration devices configured to communicate with networks and external devices are provided. In an exemplary embodiment, a drug administration device is configured to adjust an operational parameter of the drug administration device based on a data packet formed from drug administration data ancillary data received from networks and/or external devices. In another example embodiment, a drug administration device is configured to scan for and establish communications with at least one external device. In another example embodiment, a method includes assessing whether to update a control program on a drug administration device from a network or external device. In another example embodiment, a system includes a first drug administration device configured to communicate with a second drug administration device to optimize a drug treatment.

A system and method for measuring the effectiveness of a dose from an inhaler on a user is disclosed. The inhaler includes a drug container and a dosing mechanism coupled to the drug container to aerate a dose from the drug container. The dosing mechanism provides the aerated dose to the user. A sensor interface is in communication with a physiological sensor. The physiological sensor is attached to a user to sense a physiological response to the dose. Physiological data is sent to the sensor interface. A controller is coupled to the sensor interface to collect the sensed physiological data from the user corresponding to the time that the aerated dose is delivered to the user. The effectiveness of the dose may be determined from the collected data. The dose amount or frequency may be changed or the drug may be changed based on the collected data.

A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising: a substance supply unit for supplying a dose of substance to be delivered to the nasal cavity of the subject, the substance supply unit including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the substance supply unit; and a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the substance supply unit and through which the subject in use exhales such as to entrain substance from the container chamber and deliver the same through the nosepiece, and at least one temperature modifier for reducing a temperature of the exhaled air flow such as to reduce the absolute humidity thereof.

A dry powder delivery device may be configured to provide micronized dry powder particles to airways of a user. The device may include a cylindrical container delimiting a chamber containing at least one magnetically-responsive object, a motor external to said chamber, a magnet external to the chamber and rotatably coupled with the motor, and an outflow member configured to direct airflow to a user. The magnetically-responsive object may be coated with micronized dry powder particles, and the motor may be operable to rotate the magnet about an axis. Rotation of the magnet creates a magnetic field that causes the magnetically-responsive object to move in response to the magnetic field and collide with a side wall of the container to deaggregate the dry powder particles and aerosolize the dry powder in the chamber.

A device for delivering a compound to the olfactory region of the nasal cavity includes an actuator body and a tip configured to removably couple to the actuator body. The actuator body comprises a propellant channel in fluid communication with a propellant canister. The tip comprises a tip stem, a dip tube, a delivery channel, one or more puncture members, and an outlet orifice. The tip stem receives a compound container containing the compound and the compound container moves between a sealed state and an unsealed state. The one or more puncture members are each configured to puncture the compound container when the compound container is in the unsealed state. Propellant released from the canister travels through the propellant channel and into the punctured compound container, thereby contacting the compound and propelling the compound through the delivery channel and out the outlet orifice.

A holder for an inhaler article that includes a sleeve positioned within a housing cavity, a piercing element, and a lockout mechanism. The sleeve comprises a sleeve cavity arranged to receive the inhaler article. The sleeve is movable within the housing cavity between a first and second position. The piercing element is arranged to pierce the inhaler article received within the sleeve when the sleeve is moved from the first position to the second position. The lockout mechanism comprises a guide, a follower member coupled to the sleeve, and a retaining section. The follower member is arranged to move along the guide into the retaining section as the sleeve moves from the second position and back to the first position. The retaining section is arranged to hold the follower member when the sleeve has returned back to the first position, thus retaining the sleeve in the first position.

An inhaler article includes a body extending along a longitudinal axis from a mouthpiece end to a distal end. A capsule cavity may be within the body bounded downstream by a mouthpiece. An air inlet at the distal end and an air outlet at the mouthpiece end. A first mouthpiece air channel may extend from the distal air inlet, through the capsule cavity to the mouthpiece air outlet. A second mouthpiece air channel may extend from a point downstream of the separator to the mouthpiece air outlet. The second mouthpiece air channel may be separate from the first mouthpiece air channel. A coating layer of flavour may be disposed on a surface of the second mouthpiece air channel and a protective layer may be disposed on the coating layer of flavour.

A capsule article (100) includes a polymeric body (110) extending along a longitudinal axis from a first end to a second end and defining a capsule cavity (105) containing powder, and a metal foil (120) and a sealant layer (130) covering an outer surface of the polymeric body. A method of forming a hermetic capsule includes the steps of wrapping a capsule, with a metal foil; and enclosing the capsule with a sealant layer to form a hermetic barrier enclosing the capsule.